Reaction transcription in_re717 map

gIRF1@INNATE_IMMUNE_CELL_Cytosol map → rIRF1@INNATE_IMMUNE_CELL_Cytosol map

Reaction regulators:
Catalysis
  1. STAT1|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
  2. STAT5*|​pho@INNATE_IMMUNE_CELL_Cytosol map
  3. TNF:​TNFR2*:​TRAF1:​TRAF2@INNATE_IMMUNE_CELL_Membrane map


References
PMID:12433365
INFG induces SOCS1 expression in macrophages.
PMID:10820262
Probably IFNG induces SOCS1 expressiov via IRF1 upregulation downstream of STAT1
PMID:18345002
TNF induces IRF1 expression both through TNFR1 and TNFR2.
TNF induced IFNB expression through IRF1