Reaction transcription in_re513
gCCR2@INNATE_IMMUNE_CELL_Cytosol
→ rCCR2@INNATE_IMMUNE_CELL_Cytosol
Reaction regulators:
- Catalysis
- HIF2A*@INNATE_IMMUNE_CELL_Cytosol
- Inhibition
- TNF@default
References
PMID:10623817
CCR2 ligands regulates recruiting monocytes/macrophages to tumors.
TNF inhibit CCR2 expression in tumor associated macrophages.