Reaction state_transition in_re499 map

Cystine@default map → Cysteine@default map

Reaction regulators:
Catalysis
  1. TXN@default map


References
PMID:20414655, PMID:18792398
Trx is one of the main intracellular oxido-reductases
TXN expression is upregulated in activated macrophages,
DC and probably macrophages secrete thioredoxin which reduces extracellular cystine to cysteine, which is then available for the uptake by T cells through their ASC transporter