Reaction state_transition in_re444
STAT1@INNATE_IMMUNE_CELL_Cytosol
→ STAT1|pho|active@INNATE_IMMUNE_CELL_Cytosol
Reaction regulators:
- Catalysis
- IL13:IL13RA1|pho:IL4R|pho:JAK1:JAK2|pho:TYK2|pho@INNATE_IMMUNE_CELL_Membrane
References
PMID:23124025
Tyk2 but not Jak2 is involved in regulating the IL-13-stimulated activation of Stat1(TYR701)
PMID:12223527
Stat proteins 1 alpha, 3, 5A, 5B, and 6 are phosphorylated in response to IL-13.