Identifiers
matrix metallopeptidase 13
HUGO:MMP13 hgnc_id:HGNC:7159 HGNC:7159 ENTREZ:4322 UNIPROT:P45452
matrix metallopeptidase 13 (membrane-inserted)
HUGO:MMP13, HGNC:7159, ENTREZ:4322, GENECARDS:GC11M102847, UNIPROT:P45452
HUGO:MMP13
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
Cancer Associated Fibroblasts / MATRIX_REGULATION
EMT Senescence / EMT_REGULATORS
EMT Senescence / ECM
Innate Immunity / TUMOR_GROWTH
References
CASCADE:INTEGRIN
PMID:17420280
Analysis of matrix metalloproteinase in vitro and in vivo revealed disturbed MMP13 and MMP14 synthesis in alpha11(-/-) cells.
PMID:21900405
MMP13 activates TGFB by cleavage of LAP
MDSC
PMID:18633355
MDSC isolated from murine tumours express higher levels of various MMPs (MMP2, MMP9, MMP13 and MMP14 than MDSC from healthy mice