Protein ALOX15 map

Identifiers
arachidonate 15-lipoxygenase
HUGO:ALOX15 HGNC:433 ENTREZ:246 UNIPROT:P16050
HUGO:ALOX15
CASCADE:IL4
CASCADE:IL13

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / NECROPTOSIS  map
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPPRESSIVE_CORE_PATHWAYS  map

References
PMID:10432118
ALOX15 activation results in induction of CD36 expression downstream of IL4 and IL13 via PRARG
Linoleic acid is oxygenated by ALOX15 to 13-HODE which activates PPARG.

ALOX15@INNATE_IMMUNE_CELL_Cytosol

References
in_re1106( Innate Immunity  map ):
PMID:10432118
Linoleic acid is oxygenated by ALOX15 to 13-HODE which activates PPARG.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. ALOX15@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rALOX15@INNATE_IMMUNE_CELL_Cytosol map → map ALOX15@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. linoleic acid@INNATE_IMMUNE_CELL_Cytosol map → map 13(S)-HPODE@INNATE_IMMUNE_CELL_Cytosol map