Antisense RNA MIR212
Identifiers
HUGO:MIR212
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS
Innate Immunity
/ MIRNA_TF_IMMUNOSTIMULATORY
References
NATURAL_KILLER
CASCADE:IL12
PMID:22077060
The miRs-132, 212, and 200a were shown to be induced in human NK cells by IL-12 stimulation, which in turn target STAT4 mRNA, thereby providing a negative regulatory pathway for IL-12 signaling.
Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- arMIR212@INNATE_IMMUNE_CELL_Cytosol
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- MIR212:STAT4@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- gMIR212@INNATE_IMMUNE_CELL_Cytosol
→
arMIR212@INNATE_IMMUNE_CELL_Cytosol
- rSTAT4@INNATE_IMMUNE_CELL_Cytosol
+ arMIR212@INNATE_IMMUNE_CELL_Cytosol
→
MIR212:STAT4@INNATE_IMMUNE_CELL_Cytosol
- MIR212:STAT4@INNATE_IMMUNE_CELL_Cytosol
→
degraded
As Catalyser: