Antisense RNA MIR132
Identifiers
HUGO:MIR132
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS
Innate Immunity
/ MIRNA_TF_IMMUNOSTIMULATORY
References
CASCADE:IL12
NATURAL_KILLER
PMID:22077060
The miRs-132, 212, and 200a were shown to be induced in human NK cells by IL-12 stimulation, which in turn target STAT4 mRNA, thereby providing a negative regulatory pathway for IL-12 signaling.
Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- arMIR132@INNATE_IMMUNE_CELL_Cytosol
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- MIR132:STAT4@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- gMIR132@INNATE_IMMUNE_CELL_Cytosol
→
arMIR132@INNATE_IMMUNE_CELL_Cytosol
- rSTAT4@INNATE_IMMUNE_CELL_Cytosol
+ arMIR132@INNATE_IMMUNE_CELL_Cytosol
→
MIR132:STAT4@INNATE_IMMUNE_CELL_Cytosol
- MIR132:STAT4@INNATE_IMMUNE_CELL_Cytosol
→
degraded
As Catalyser: