Protein STAB2 map

Identifiers
HUGO:STAB2

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / DANGER_SIGNAL_PATHWAYS  map

References
 MACROPHAGE  map
CASCADE:STAB2
PMID:17962816
The downregulation of stabilin-2 expression in macrophages significantly inhibits phagocytosis, and anti-stabilin-2 monoclonal antibody provokes the release of the anti-inflammatory cytokine, transforming growth factor-beta. Furthermore, the results of time-lapse video analyses indicate that stabilin-2 performs a crucial function in the rapid clearance of aged and apoptotic cells.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. STAB2@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. PtdSer:​STAB2@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. PtdSer:​STAB2@INNATE_IMMUNE_CELL_Membrane map → map EXOCYTOSIS_AND_PHAGOCYTOSIS@INNATE_IMMUNE_CELL_Membrane map
  2. PtdSer@TUMOR_CELL_AS_INDUCTOR_Membrane map + STAB2@INNATE_IMMUNE_CELL_Membrane map → map PtdSer:​STAB2@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. TGFB*@INNATE_IMMUNE_CELL_Cytosol map → map TGFB*@default map