Identifiers
HUGO:IL1RN
References
PMID:20580461
IRF4 regulates expression of some IL4-dependent genes.
IRF4 upregulates expression of CIITA, CYP1B1, CCL24, MPP6,
and downregulate expression IL1RN.
PMID:15218058
Stat3 binds ILR1N promoter and upregulates expression of IL1RN downstream of IL10
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses.
PMID:10952726
HMGB1 induces expression of proinflammotory cytokines IL1A,IL1B,IL1RA,IL6, IL8, MIP1A,MIP1B
References
in_re640( Innate Immunity ):
PMID:10952726
HMGB1 upregulates protein level of IL1RN (IL1RA)