RNA TBX21 map

Identifiers
HUGO:TBX21

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / INHIBITING_CHECKPOINTS  map
 Innate Immunity  map  / MIRNA_TF_IMMUNOSTIMULATORY  map

References
PMID:26885856
 NATURAL_KILLER  map
 MACROPHAGE  map
 DENDRITIC_CELL  map
CASCADE:TGFB
CASCADE:Fc_gamma_RIII
CASCADE:IL2
CASCADE:IL15
CASCADE:IL18
CASCADE:IL12
CASCADE:IL21
CASCADE:IFNG
PMID:10761931, PMID:12055627, PMID:18768831, PMID:16713975
The pattern of T-bet expression correlates well with the production of IFNG in NK cells.
The induction of T-bet expression and secretion of IFN?? in NK cells that produce IFN??
exists only upon treatment with IL-2, IL15,IL18 and IL-12 and CD16 pathway activation..
T-bet regulates IFNG expression in NK cells, probably via chromatin remodeling.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. rTBX21@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rTBX21@INNATE_IMMUNE_CELL_Cytosol map → map TBX21@INNATE_IMMUNE_CELL_Cytosol map
    2. gTBX21@INNATE_IMMUNE_CELL_Cytosol map → map rTBX21@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: