Protein IL12p40* map

Identifiers
HUGO:IL12B

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS  map
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_EXPRESSION  map

References
PMID:16243976
IRF4 downregulates expression of TNFa, IL12p40, IL6 probably via inhibition of NF-kB and JNK signaling pathways.
PMID:12417340
IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 p40 promoter activity in macrophages.
IRF-1 can be acetylated by p300. p300 is recruited to the IL-12p40 promoter depending on both ICSBP and IRF-1
and acts as coactivator.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. IL12p40*@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. IL12p40*@INNATE_IMMUNE_CELL_Cytosol map → map IL12*@INNATE_IMMUNE_CELL_Cytosol map
    2. rIL12p40*@INNATE_IMMUNE_CELL_Cytosol map → map IL12p40*@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: