Gene ULBP2 map

Identifiers
HUGO:ULBP2

References
 NATURAL_KILLER  map
PMID:22754780, PMID:21764762
Wild-type p53, but not mutant p53 interacts with UDLPs promoters and induces UDLP2 and UDLP1 expression in tumor cells and increases tumor immunogenicity.
UDLPs activate NKG2D* signaling in NK cells.Induction of wtp53 expression in tumor cells leads to their enhanced recognition by primary NK cells in a NKG2D-dependent manner.
PMID:25277195
Hypoxia down-regulates level of MICA, MICB, ULBP2 and ULBP3 transcripts in tumors.

Modifications:
In compartment: TUMOR_CELL_AS_INDUCTOR
  1. gULBP2@TUMOR_CELL_AS_INDUCTOR map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gULBP2@TUMOR_CELL_AS_INDUCTOR map → map rULBP2@TUMOR_CELL_AS_INDUCTOR map
    As Catalyser: