Protein CX3CL1 map

Identifiers
HUGO:CX3CL1

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / DANGER_SIGNAL_PATHWAYS  map
 Innate Immunity  map  / RECRUITMENT_OF_IMMUNE_CELLS  map

References
 DENDRITIC_CELL  map
 NATURAL_KILLER  map
 MACROPHAGE  map
CASCADE:CX3CR1
PMID:18799722
CX3CL1/fractalkine is released from dying cells
PMID:18363071
Fractalkine (CX3CL1) is the only CX3C chemokine that can chemoattract natural killer (NK) cells, CD8+ T cells, monocytes, and dendritic cells.
PMID:12455035
CX3CL1 induces chemoattraction and activation of DC via CX3CR1 and induces Tcell activation. Adherence of DC to cells expressed CX3CL1 resulted in phenotypic maturation and upregulated IL-12 secretion of DC, and more strong stimulation of allogeneic T-cell proliferation by DC.

Modifications:
In compartment: default
  1. CX3CL1@default map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CX3CR1:​CX3CL1@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. CX3CR1:​CX3CL1@INNATE_IMMUNE_CELL_Membrane map → map RECRUITMENT_OF_IMMUNE_CELLS@INNATE_IMMUNE_CELL_Cytosol map
  2. FIND_ME@TUMOR_CELL_AS_INDUCTOR map → map CX3CL1@default map
  3. CX3CL1@default map + CX3CR1@INNATE_IMMUNE_CELL_Membrane map → map CX3CR1:​CX3CL1@INNATE_IMMUNE_CELL_Membrane map
As Catalyser: