Identifiers
HUGO:NFKBID
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity / IMMUNOSTIMULATORY_CORE_PATHWAYS
References
PMID:15749903, PMID:16413922
NFKBID (IkBNS) interacts with NFkB p50 inhibit recrutement NFkB p50/p65 to IL-6 promoter
and inhibit IL6 expression.
PMID:16413922
NFKBID (IkBNS) inhibit late phase (after 3h) of expression of proinflanotory cytokines
Il-12p40 (IL-12p40), Il-18 (IL-18) and Csf3 (G_CSF).
References
in_re558( Innate Immunity ):
PMID:17485448
Inhibition of??? ???NFkB signaling downstream of??? ???ABIN3??? ???
inhibits expression of??? ???IL8,??? ???IL6,??? ???TNF,??? ???IL12
PMID:16413922
NFKBID (IkBNS) inhibit late phase (after 3h) of expression of proinflanotory cytokines
Il-12p40 (IL-12p40), Il-18 (IL-18) and Csf3 (G_CSF).
PMID:16243976
IRF4 downregulates expression of TNFa, IL12p40, IL6 probably via inhibition of NF-kB and JNK signaling pathways.
PMID:17404308
CSF1 downregulates TNF, IL-23p19, IL-12p40 expression probably via induction of acomulation of p50 homodimer and inhibition of p65/p50 NF-kB signaling.
CSF2 upregulates expression of TNF, and have positive influence on IL12p70 (p40+p35), IL23 (p40+p19) expression, probably via induction rapid IkBa degradetion, RELA nuclear translocation and formation p65/p50 heterodimers provided induction of NFkB signaling.
PMID:23390297
MIF inhitits expression of M1 markers such as IL12p40