Protein CTSL map

Identifiers
HUGO:CTSL

References
 DENDRITIC_CELL  map
PMID:22157818
CTSS (cathepsin S), CTSB (cathepsin B) and CTSL (cathepsin L) are active in DC phagosomes.
Phagosomal NOX2 activity via ROS inhibits the activities of local cysteine (B/S/L ), but not aspartic (D/E), cathepsins
PMID:12776207
Cathepsins B,D,L, S and AEP (LGMN) are the lysosomal proteases implicated in antigen presentation in DC.

Modifications:
In compartment: PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
  1. CTSL@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. Tumor_antigen@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map → map Tumor_antigen_fragment@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map