Protein CTSD map

Identifiers
cathepsin D
HUGO:CTSD HGNC:2529 ENTREZ:1509 UNIPROT:P07339
HUGO:CTSD

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / NECROPTOSIS  map

References
PMID:22439866
Several components of ECM, such as fibronectin, proteoglycans, and collagens, are substrates for CTSD(cathepsin D)
PMID:18955971
 DENDRITIC_CELL  map
PMID:16237087
CTSD (aspartic cathepsin D) and CTSG (cathepsin G) participate in antigen processing in DC.
PMID:12776207
Cathepsins B,D,L, S and AEP (LGMN) are the lysosomal proteases implicated in antigen presentation in DC.

Modifications:
In compartment: PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
  1. CTSD@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. Tumor_antigen@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map → map Tumor_antigen_fragment@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map