Protein TSC2 map

Identifiers
HUGO:TSC2
tuberous sclerosis 2
HUGO:TSC2 HGNC:12363 ENTREZ:7249 UNIPROT:P49815
HUGO:TSC2 HGNC:12363 ENTREZ:7249 UNIPROT:P49815 GENECARDS:TSC2 REACTOME:404219 KEGG:7249 ATLASONC:TSC2ID184 WIKI:TSC2
P49815

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / TCR_SIGNALING  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / MOMP_REGULATION  map
 Innate Immunity  map  / IMMUNOSTIMULATORY_CORE_PATHWAYS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / HEDGEHOG  map
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:12906785 PMID:19022819
AKT activates Rapamycin associated protein FRAP2 ( mTOR ) probably through Tuberin/GTP-binding protein Ras homolog enriched in brain ( RHEB ) pathway.
PMID:17680028
PMID:16636147
PMID:20146692

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. TSC1:​TSC2@INNATE_IMMUNE_CELL_Cytosol map
  2. TSC1:​TSC2|​pho@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. TSC1:​TSC2@INNATE_IMMUNE_CELL_Cytosol map → map TSC1:​TSC2|​pho@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. (GTP:​RHEB)|​active@INNATE_IMMUNE_CELL_Cytosol map + GDP@INNATE_IMMUNE_CELL_Cytosol map → map GDP:​RHEB@INNATE_IMMUNE_CELL_Cytosol map + GTP@INNATE_IMMUNE_CELL_Cytosol map