Protein IRAP map

Identifiers
HUGO:IRAP

References
 DENDRITIC_CELL  map
PMID:22790179, PMID:19498108
Proteasome-generated polypeptides need to be trimmed by amino-terminal peptidases to be loaded on MHC class I molecules, and both ER-associated aminopeptidase 1 (ERAP1)6 and endosomal insulin-responsive aminopeptidase (IRAP; also known as cystinyl aminopeptidase)7 have been shown to be involved in cross-presentation.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. IRAP@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. Tumor_antigen@INNATE_IMMUNE_CELL_Cytosol map → map Tumor_antigen_fragment@INNATE_IMMUNE_CELL_Cytosol map