Protein HDAC* map

Identifiers
HUGO:HDAC1 HGNC:4852 ENTREZ:3065 UNIPROT:Q13547 GENECARDS:HDAC1 HUGO:HDAC2 HGNC:4853 ENTREZ:3066 UNIPROT:Q92769 GENECARDS:HDAC2 HUGO:HDAC3 HGNC:4854 ENTREZ:8841 UNIPROT:O15379 GENECARDS:HDAC3 HUGO:HDAC4 HGNC:14063 ENTREZ:9759 UNIPROT:P56524 GENECARDS:HDAC4 HUGO:HDAC5 HGNC:14068 ENTREZ:10014 UNIPROT:Q9UQL6 GENECARDS:HDAC5 HUGO:HDAC6 HGNC:14064 ENTREZ:10013 UNIPROT:Q9UBN7 GENECARDS:HDAC6 HUGO:HDAC7 HGNC:14067 ENTREZ:51564 UNIPROT:Q8WUI4 GENECARDS:HDAC7 HUGO:HDAC8 HGNC:13315 ENTREZ:55869 UNIPROT:Q9BY41 GENECARDS:HDAC8 HUGO:HDAC10 HGNC:18128 ENTREZ:83933 UNIPROT:Q969S8 GENECARDS:HDAC10 HUGO:HDAC11 HGNC:19086 ENTREZ:79885 UNIPROT:Q96DB2 GENECARDS:HDAC11
histone deacetylase 1
HUGO:HDAC1 HGNC:4852 ENTREZ:3065 UNIPROT:Q13547 GENECARDS:HDAC1 REACTOME:56408 KEGG:3065 ATLASONC:GC_HDAC1 WIKI:HDAC1
histone deacetylase 2
HUGO:HDAC2 HGNC:4853 ENTREZ:3066 UNIPROT:Q92769 GENECARDS:HDAC2 REACTOME:56410 KEGG:3066 ATLASONC:HDAC2ID40803ch6q22 WIKI:HDAC2
histone deacetylase 3
HUGO:HDAC3 HGNC:4854 ENTREZ:8841 UNIPROT:O15379 GENECARDS:HDAC3 REACTOME:401336 KEGG:8841 ATLASONC:HDAC3ID40804ch5q31 WIKI:HDAC3
histone deacetylase 4
HUGO:HDAC4 HGNC:14063 ENTREZ:9759 UNIPROT:P56524 GENECARDS:HDAC4 REACTOME:56414 KEGG:9759 ATLASONC:GC_HDAC4 WIKI:HDAC4
histone deacetylase 5
HUGO:HDAC5 HGNC:14068 ENTREZ:10014 UNIPROT:Q9UQL6 GENECARDS:HDAC5 REACTOME:415622 KEGG:10014 ATLASONC:GC_HDAC5 WIKI:HDAC5
histone deacetylase 6
HUGO:HDAC6 HGNC:14064 ENTREZ:10013 UNIPROT:Q9UBN7 GENECARDS:HDAC6 REACTOME:56418 KEGG:10013 ATLASONC:GC_HDAC6 WIKI:HDAC6
histone deacetylase 7
HUGO:HDAC7 HGNC:14067 ENTREZ:51564 UNIPROT:Q8WUI4 GENECARDS:HDAC7 REACTOME:412089 KEGG:9734 ATLASONC:GC_HDAC7 WIKI:HDAC7
histone deacetylase 8
HUGO:HDAC8 HGNC:13315 ENTREZ:55869 UNIPROT:Q9BY41 GENECARDS:HDAC8 REACTOME:148335 KEGG:55869 ATLASONC:GC_HDAC8 WIKI:HDAC8
histone deacetylase 10
HUGO:HDAC10 HGNC:18128 ENTREZ:83933 UNIPROT:Q969S8 GENECARDS:HDAC10 REACTOME:412605 KEGG:83933 ATLASONC:GC_HDAC10 WIKI:HDAC10
histone deacetylase 11
HUGO:HDAC11 HGNC:19086 ENTREZ:79885 UNIPROT:Q96DB2 GENECARDS:HDAC11 REACTOME:56406 KEGG:79885 ATLASONC:GC_HDAC11 WIKI:HDAC11

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_NON_CANONICAL  map

References
histone deacetylase 1
REACTOME:56408 KEGG:3065 ATLASONC:GC_HDAC1 WIKI:HDAC1
histone deacetylase 2
REACTOME:56410 KEGG:3066 ATLASONC:HDAC2ID40803ch6q22 WIKI:HDAC2
histone deacetylase 3
REACTOME:401336 KEGG:8841 ATLASONC:HDAC3ID40804ch5q31 WIKI:HDAC3
histone deacetylase 4
REACTOME:56414 KEGG:9759 ATLASONC:GC_HDAC4 WIKI:HDAC4
histone deacetylase 5
REACTOME:415622 KEGG:10014 ATLASONC:GC_HDAC5 WIKI:HDAC5
histone deacetylase 6
REACTOME:56418 KEGG:10013 ATLASONC:GC_HDAC6 WIKI:HDAC6
histone deacetylase 7
REACTOME:412089 KEGG:9734 ATLASONC:GC_HDAC7 WIKI:HDAC7
histone deacetylase 8
REACTOME:148335 KEGG:55869 ATLASONC:GC_HDAC8 WIKI:HDAC8
histone deacetylase 10
0 0 REACTOME:412605 KEGG:83933 ATLASONC:GC_HDAC10 WIKI:HDAC10
histone deacetylase 11
1 1 REACTOME:56406 KEGG:79885 ATLASONC:GC_HDAC11 WIKI:HDAC11
 NATURAL_KILLER  map
 MACROPHAGE  map
PMID:23801635
B7H6 (NCR3LG) is a Nkp30 ligand.It is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3) results in natural killer (NK) cell activation and cytotoxicity.
Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells.
PMID:17689680
STAT1 acetilation inhibits its activity in macrophages.

HDAC*@INNATE_IMMUNE_CELL_Cytosol

References
in_re711( Innate Immunity  map ):
PMID:17689680
HDACs provide STAT1 deacetylation and activation.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. HDAC*@INNATE_IMMUNE_CELL_Cytosol map
In compartment: TUMOR_CELL_AS_INDUCTOR
  1. HDAC*@TUMOR_CELL_AS_INDUCTOR map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. gB7H6*@TUMOR_CELL_AS_INDUCTOR map → map rB7H6*@TUMOR_CELL_AS_INDUCTOR map
      2. STAT1|​pho|​ace@INNATE_IMMUNE_CELL_Cytosol map → map STAT1|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map