{"c_s335": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s335\", \"c_s1500\"]) } catch (e) {}; return false;' title=\"c_s335 c_s1500 2 modifs\">BAF250*</a> <a href='javascript_required.html' onclick='try { show_blog(1886); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>AT rich interactive domain 1A (SWI-like)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=ARID1A' target='_blank'>HUGO:ARID1A</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=11110' target='_blank'>HGNC:11110</a> <a href='http://www.ncbi.nlm.nih.gov/gene/8289' target='_blank'>ENTREZ:8289</a> <a href='http://www.expasy.org/uniprot/O14497' target='_blank'>UNIPROT:O14497</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=ARID1A' target='_blank'>GENECARDS:ARID1A</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:8289' target='_blank'>KEGG:8289</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_ARID1A.html' target='_blank'>ATLASONC:GC_ARID1A</a> <a href='http://wikipedia.org/wiki/ARID1A' target='_blank'>WIKI:ARID1A</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s335\", \"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s335 c_s1500 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s335\", \"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s335 c_s1500 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s335\", \"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s335 c_s1500 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;WNT_CANONICAL&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/WNT_CANONICAL/index.html\", [\"c_s335\", \"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s335 c_s1500 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br>BAF250*|pho<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s335\"]); } catch (e) {}; return false;' title=\"c_s335 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR></p></span>",
"s99": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s335\", \"c_s1500\"]) } catch (e) {}; return false;' title=\"c_s335 c_s1500 2 modifs\">BAF250*</a> <a href='javascript_required.html' onclick='try { show_blog(1886); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>AT rich interactive domain 1A (SWI-like)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=ARID1A' target='_blank'>HUGO:ARID1A</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=11110' target='_blank'>HGNC:11110</a> <a href='http://www.ncbi.nlm.nih.gov/gene/8289' target='_blank'>ENTREZ:8289</a> <a href='http://www.expasy.org/uniprot/O14497' target='_blank'>UNIPROT:O14497</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=ARID1A' target='_blank'>GENECARDS:ARID1A</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:8289' target='_blank'>KEGG:8289</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_ARID1A.html' target='_blank'>ATLASONC:GC_ARID1A</a> <a href='http://wikipedia.org/wiki/ARID1A' target='_blank'>WIKI:ARID1A</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s335\", \"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s335 c_s1500 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s335\", \"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s335 c_s1500 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s335\", \"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s335 c_s1500 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;WNT_CANONICAL&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/WNT_CANONICAL/index.html\", [\"c_s335\", \"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s335 c_s1500 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s335\", \"s99\"]) } catch (e) {}; return false;' title=\"c_s335 s99 2 modifs\">BAF250*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s98\", \"s117\"]) } catch (e) {}; return false;' title=\"s98 s117 2 modifs\">DP1*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s97\", \"s116\"]) } catch (e) {}; return false;' title=\"s97 s116 2 modifs\">E2F1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s96\", \"s115\"]) } catch (e) {}; return false;' title=\"s96 s115 2 modifs\">RB1</a>|pho|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:BAF250*:DP1*:E2F1:RB1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_4.gif'/> REF=5 <span style='color:orange'>FUNC=4</span></p></span>,",
"c_s528": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CDK2</a> <a href='javascript_required.html' onclick='try { show_blog(3919); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK2' target='_blank'>HUGO:CDK2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1771' target='_blank'>HGNC:1771</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1017' target='_blank'>ENTREZ:1017</a> <a href='http://www.expasy.org/uniprot/P24941' target='_blank'>UNIPROT:P24941</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK2' target='_blank'>GENECARDS:CDK2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87018' target='_blank'>REACTOME:87018</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1017' target='_blank'>KEGG:1017</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK2.html' target='_blank'>ATLASONC:GC_CDK2</a> <a href='http://wikipedia.org/wiki/CDK2' target='_blank'>WIKI:CDK2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br>CDK2|Thr160_pho<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re250:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\"]); } catch (e) {}; return false;' title=\"c_s528 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR>c_re251:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\"]); } catch (e) {}; return false;' title=\"c_s528 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11355576' target='_blank'>PMID:11355576</a><BR></p></span>",
"c_s31": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CDK2</a> <a href='javascript_required.html' onclick='try { show_blog(3919); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK2' target='_blank'>HUGO:CDK2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1771' target='_blank'>HGNC:1771</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1017' target='_blank'>ENTREZ:1017</a> <a href='http://www.expasy.org/uniprot/P24941' target='_blank'>UNIPROT:P24941</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK2' target='_blank'>GENECARDS:CDK2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87018' target='_blank'>REACTOME:87018</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1017' target='_blank'>KEGG:1017</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK2.html' target='_blank'>ATLASONC:GC_CDK2</a> <a href='http://wikipedia.org/wiki/CDK2' target='_blank'>WIKI:CDK2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br>CDK2<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re251:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s31\"]); } catch (e) {}; return false;' title=\"c_s31 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11355576' target='_blank'>PMID:11355576</a><BR>c_re306:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s31\"]); } catch (e) {}; return false;' title=\"c_s31 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7799941' target='_blank'>PMID:7799941</a><BR></p></span>",
"s1489": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CDK2</a> <a href='javascript_required.html' onclick='try { show_blog(3919); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK2' target='_blank'>HUGO:CDK2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1771' target='_blank'>HGNC:1771</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1017' target='_blank'>ENTREZ:1017</a> <a href='http://www.expasy.org/uniprot/P24941' target='_blank'>UNIPROT:P24941</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK2' target='_blank'>GENECARDS:CDK2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87018' target='_blank'>REACTOME:87018</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1017' target='_blank'>KEGG:1017</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK2.html' target='_blank'>ATLASONC:GC_CDK2</a> <a href='http://wikipedia.org/wiki/CDK2' target='_blank'>WIKI:CDK2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s23\", \"s1490\"]) } catch (e) {}; return false;' title=\"c_s23 s1490 2 modifs\">p107*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p107*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re1275:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p></span>,",
"s1484": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CDK2</a> <a href='javascript_required.html' onclick='try { show_blog(3919); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK2' target='_blank'>HUGO:CDK2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1771' target='_blank'>HGNC:1771</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1017' target='_blank'>ENTREZ:1017</a> <a href='http://www.expasy.org/uniprot/P24941' target='_blank'>UNIPROT:P24941</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK2' target='_blank'>GENECARDS:CDK2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87018' target='_blank'>REACTOME:87018</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1017' target='_blank'>KEGG:1017</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK2.html' target='_blank'>ATLASONC:GC_CDK2</a> <a href='http://wikipedia.org/wiki/CDK2' target='_blank'>WIKI:CDK2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a>|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re1276(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>p130 binds to and inhibits CYCLINE-CDK2, independantly of its phosphorylation state.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p></span>,",
"s786": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CDK2</a> <a href='javascript_required.html' onclick='try { show_blog(3919); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK2' target='_blank'>HUGO:CDK2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1771' target='_blank'>HGNC:1771</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1017' target='_blank'>ENTREZ:1017</a> <a href='http://www.expasy.org/uniprot/P24941' target='_blank'>UNIPROT:P24941</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK2' target='_blank'>GENECARDS:CDK2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87018' target='_blank'>REACTOME:87018</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1017' target='_blank'>KEGG:1017</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK2.html' target='_blank'>ATLASONC:GC_CDK2</a> <a href='http://wikipedia.org/wiki/CDK2' target='_blank'>WIKI:CDK2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"s1512\", \"s779\", \"s775\"]) } catch (e) {}; return false;' title=\"c_s1471 s1512 s779 s775 4 modifs\">p21CIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p21CIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s787\"]); } catch (e) {}; return false;' title=\"c_s787 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s787\"]); } catch (e) {}; return false;' title=\"c_s787 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re327:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s787\"]); } catch (e) {}; return false;' title=\"c_s787 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p></span>,",
"s237": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CDK2</a> <a href='javascript_required.html' onclick='try { show_blog(3919); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK2' target='_blank'>HUGO:CDK2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1771' target='_blank'>HGNC:1771</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1017' target='_blank'>ENTREZ:1017</a> <a href='http://www.expasy.org/uniprot/P24941' target='_blank'>UNIPROT:P24941</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK2' target='_blank'>GENECARDS:CDK2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87018' target='_blank'>REACTOME:87018</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1017' target='_blank'>KEGG:1017</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK2.html' target='_blank'>ATLASONC:GC_CDK2</a> <a href='http://wikipedia.org/wiki/CDK2' target='_blank'>WIKI:CDK2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"s649\", \"s653\", \"s652\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 s649 s653 s652 5 modifs\">p27KIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p27KIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re170(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Complex CYCLINE-CDK2 inhibited by its interaction with CKI.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p></span>,",
"s216": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CDK2</a> <a href='javascript_required.html' onclick='try { show_blog(3919); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK2' target='_blank'>HUGO:CDK2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1771' target='_blank'>HGNC:1771</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1017' target='_blank'>ENTREZ:1017</a> <a href='http://www.expasy.org/uniprot/P24941' target='_blank'>UNIPROT:P24941</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK2' target='_blank'>GENECARDS:CDK2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87018' target='_blank'>REACTOME:87018</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1017' target='_blank'>KEGG:1017</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK2.html' target='_blank'>ATLASONC:GC_CDK2</a> <a href='http://wikipedia.org/wiki/CDK2' target='_blank'>WIKI:CDK2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Tyr14_pho|Tyr15_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s741\"]); } catch (e) {}; return false;' title=\"c_s741 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s741\"]); } catch (e) {}; return false;' title=\"c_s741 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p></span>,",
"s215": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CDK2</a> <a href='javascript_required.html' onclick='try { show_blog(3919); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK2' target='_blank'>HUGO:CDK2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1771' target='_blank'>HGNC:1771</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1017' target='_blank'>ENTREZ:1017</a> <a href='http://www.expasy.org/uniprot/P24941' target='_blank'>UNIPROT:P24941</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK2' target='_blank'>GENECARDS:CDK2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87018' target='_blank'>REACTOME:87018</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1017' target='_blank'>KEGG:1017</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK2.html' target='_blank'>ATLASONC:GC_CDK2</a> <a href='http://wikipedia.org/wiki/CDK2' target='_blank'>WIKI:CDK2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re147(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7629134' target='_blank'>PMID:7629134</a><BR>c_re169(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of p27 by cyclin E/CDK2 at Thr-187 results in targeting p27 for its degradation by proteolysis<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR>c_re248(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Cyclin E phosphorylation by CDK2 at Thr-380.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR>Autophosphorylation of the complex CYCLINE/CDK2 at Thr-380 and Thr-62. Phosphorylation at Thr-380 also by GSK-3B. Two other sites of regulation: Ser-372 et Ser-384<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16131838' target='_blank'>PMID:16131838</a><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR>c_re327:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR>c_re1275:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR>c_re1276(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>p130 binds to and inhibits CYCLINE-CDK2, independantly of its phosphorylation state.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>,",
"s218": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CDK2</a> <a href='javascript_required.html' onclick='try { show_blog(3919); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK2' target='_blank'>HUGO:CDK2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1771' target='_blank'>HGNC:1771</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1017' target='_blank'>ENTREZ:1017</a> <a href='http://www.expasy.org/uniprot/P24941' target='_blank'>UNIPROT:P24941</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK2' target='_blank'>GENECARDS:CDK2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87018' target='_blank'>REACTOME:87018</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1017' target='_blank'>KEGG:1017</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK2.html' target='_blank'>ATLASONC:GC_CDK2</a> <a href='http://wikipedia.org/wiki/CDK2' target='_blank'>WIKI:CDK2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>|Thr380_pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s722\"]); } catch (e) {}; return false;' title=\"c_s722 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s722\"]); } catch (e) {}; return false;' title=\"c_s722 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re248(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s722\"]); } catch (e) {}; return false;' title=\"c_s722 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Cyclin E phosphorylation by CDK2 at Thr-380.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR>Autophosphorylation of the complex CYCLINE/CDK2 at Thr-380 and Thr-62. Phosphorylation at Thr-380 also by GSK-3B. Two other sites of regulation: Ser-372 et Ser-384<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16131838' target='_blank'>PMID:16131838</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/1_5.gif'/> REF=1 <span style='color:red'>FUNC=5</span></p></span>,",
"s212": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CDK2</a> <a href='javascript_required.html' onclick='try { show_blog(3919); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK2' target='_blank'>HUGO:CDK2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1771' target='_blank'>HGNC:1771</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1017' target='_blank'>ENTREZ:1017</a> <a href='http://www.expasy.org/uniprot/P24941' target='_blank'>UNIPROT:P24941</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK2' target='_blank'>GENECARDS:CDK2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87018' target='_blank'>REACTOME:87018</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1017' target='_blank'>KEGG:1017</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK2.html' target='_blank'>ATLASONC:GC_CDK2</a> <a href='http://wikipedia.org/wiki/CDK2' target='_blank'>WIKI:CDK2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s528\", \"c_s31\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s528 c_s31 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re306:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7799941' target='_blank'>PMID:7799941</a><BR>c_re147(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7629134' target='_blank'>PMID:7629134</a><BR>c_re170(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Complex CYCLINE-CDK2 inhibited by its interaction with CKI.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p></span>,",
"s780": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s781\", \"c_s725\"]) } catch (e) {}; return false;' title=\"c_s781 c_s725 2 modifs\">CDK4</a> <a href='javascript_required.html' onclick='try { show_blog(4010); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 4<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK4' target='_blank'>HUGO:CDK4</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1773' target='_blank'>HGNC:1773</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1019' target='_blank'>ENTREZ:1019</a> <a href='http://www.expasy.org/uniprot/P11802' target='_blank'>UNIPROT:P11802</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK4' target='_blank'>GENECARDS:CDK4</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68329' target='_blank'>REACTOME:68329</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1019' target='_blank'>KEGG:1019</a> <a href='http://atlasgeneticsoncology.org//Genes/CDK4ID238ch12q14.html' target='_blank'>ATLASONC:CDK4ID238ch12q14</a> <a href='http://wikipedia.org/wiki/CDK4' target='_blank'>WIKI:CDK4</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s781\", \"c_s725\"]); } catch (e) {}; return false;' title=\"c_s781 c_s725 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s781\", \"c_s725\"]); } catch (e) {}; return false;' title=\"c_s781 c_s725 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\", \"c_s725\"]); } catch (e) {}; return false;' title=\"c_s781 c_s725 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLIND&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLIND/index.html\", [\"c_s781\", \"c_s725\"]); } catch (e) {}; return false;' title=\"c_s781 c_s725 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>The native protein is first correctly folded by HSP90 and CDC37 before being able to bind to the D-type cyclins.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10498883' target='_blank'>PMID:10498883</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s780\", \"s253\"]) } catch (e) {}; return false;' title=\"s780 s253 2 modifs\">CDK4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"s1512\", \"s779\", \"s775\"]) } catch (e) {}; return false;' title=\"c_s1471 s1512 s779 s775 4 modifs\">p21CIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK4:CyclinD*:p21CIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re325:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>,",
"s253": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s781\", \"c_s725\"]) } catch (e) {}; return false;' title=\"c_s781 c_s725 2 modifs\">CDK4</a> <a href='javascript_required.html' onclick='try { show_blog(4010); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 4<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK4' target='_blank'>HUGO:CDK4</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1773' target='_blank'>HGNC:1773</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1019' target='_blank'>ENTREZ:1019</a> <a href='http://www.expasy.org/uniprot/P11802' target='_blank'>UNIPROT:P11802</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK4' target='_blank'>GENECARDS:CDK4</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68329' target='_blank'>REACTOME:68329</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1019' target='_blank'>KEGG:1019</a> <a href='http://atlasgeneticsoncology.org//Genes/CDK4ID238ch12q14.html' target='_blank'>ATLASONC:CDK4ID238ch12q14</a> <a href='http://wikipedia.org/wiki/CDK4' target='_blank'>WIKI:CDK4</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s781\", \"c_s725\"]); } catch (e) {}; return false;' title=\"c_s781 c_s725 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s781\", \"c_s725\"]); } catch (e) {}; return false;' title=\"c_s781 c_s725 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\", \"c_s725\"]); } catch (e) {}; return false;' title=\"c_s781 c_s725 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLIND&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLIND/index.html\", [\"c_s781\", \"c_s725\"]); } catch (e) {}; return false;' title=\"c_s781 c_s725 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>The native protein is first correctly folded by HSP90 and CDC37 before being able to bind to the D-type cyclins.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10498883' target='_blank'>PMID:10498883</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s780\", \"s253\"]) } catch (e) {}; return false;' title=\"s780 s253 2 modifs\">CDK4</a>|Thr172_pho:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"s649\", \"s653\", \"s652\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 s649 s653 s652 5 modifs\">p27KIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK4:CyclinD*:p27KIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re175(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>,",
"s774": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s776\", \"c_s724\"]) } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\">CDK6</a> <a href='javascript_required.html' onclick='try { show_blog(4005); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 6<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK6' target='_blank'>HUGO:CDK6</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1777' target='_blank'>HGNC:1777</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1021' target='_blank'>ENTREZ:1021</a> <a href='http://www.expasy.org/uniprot/Q00534' target='_blank'>UNIPROT:Q00534</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK6' target='_blank'>GENECARDS:CDK6</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68335' target='_blank'>REACTOME:68335</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1021' target='_blank'>KEGG:1021</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK6.html' target='_blank'>ATLASONC:GC_CDK6</a> <a href='http://wikipedia.org/wiki/CDK6' target='_blank'>WIKI:CDK6</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s776\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s776\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s776\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s776\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLIND&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLIND/index.html\", [\"c_s776\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>Like CDK4, CDK6 has first to be folded by HSP90 and CDC37 before being able to bind D-type cyclins.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10498883' target='_blank'>PMID:10498883</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s774\", \"s250\"]) } catch (e) {}; return false;' title=\"s774 s250 2 modifs\">CDK6</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"s1512\", \"s779\", \"s775\"]) } catch (e) {}; return false;' title=\"c_s1471 s1512 s779 s775 4 modifs\">p21CIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK6:CyclinD*:p21CIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re324:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16775416' target='_blank'>PMID:16775416</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>,",
"s250": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s776\", \"c_s724\"]) } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\">CDK6</a> <a href='javascript_required.html' onclick='try { show_blog(4005); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 6<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK6' target='_blank'>HUGO:CDK6</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1777' target='_blank'>HGNC:1777</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1021' target='_blank'>ENTREZ:1021</a> <a href='http://www.expasy.org/uniprot/Q00534' target='_blank'>UNIPROT:Q00534</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK6' target='_blank'>GENECARDS:CDK6</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68335' target='_blank'>REACTOME:68335</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1021' target='_blank'>KEGG:1021</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK6.html' target='_blank'>ATLASONC:GC_CDK6</a> <a href='http://wikipedia.org/wiki/CDK6' target='_blank'>WIKI:CDK6</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s776\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s776\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s776\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s776\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLIND&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLIND/index.html\", [\"c_s776\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s776 c_s724 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>Like CDK4, CDK6 has first to be folded by HSP90 and CDC37 before being able to bind D-type cyclins.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10498883' target='_blank'>PMID:10498883</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s774\", \"s250\"]) } catch (e) {}; return false;' title=\"s774 s250 2 modifs\">CDK6</a>|Thr_pho:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"s649\", \"s653\", \"s652\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 s649 s653 s652 5 modifs\">p27KIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK6:CyclinD*:p27KIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re174(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_4.gif'/> REF=5 <span style='color:orange'>FUNC=4</span></p></span>,",
"s209": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s749\"]) } catch (e) {}; return false;' title=\"c_s749 1 modifs\">CDK7</a> <a href='javascript_required.html' onclick='try { show_blog(1085); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase 7<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDK7' target='_blank'>HUGO:CDK7</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1778' target='_blank'>HGNC:1778</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1022' target='_blank'>ENTREZ:1022</a> <a href='http://www.expasy.org/uniprot/P50613' target='_blank'>UNIPROT:P50613</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDK7' target='_blank'>GENECARDS:CDK7</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87028' target='_blank'>REACTOME:87028</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1022' target='_blank'>KEGG:1022</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDK7.html' target='_blank'>ATLASONC:GC_CDK7</a> <a href='http://wikipedia.org/wiki/CDK7' target='_blank'>WIKI:CDK7</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;NER&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/NER/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINH&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINH/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s209\"]) } catch (e) {}; return false;' title=\"s209 1 modifs\">CDK7</a>|Thr170_pho:<a href='javascript_required.html' onclick='try { show_markers([\"s210\"]) } catch (e) {}; return false;' title=\"s210 1 modifs\">CyclinH*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s211\"]) } catch (e) {}; return false;' title=\"s211 1 modifs\">MNAT1</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK7:CyclinH*:MNAT1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINH&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINH/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re245(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK7 activation by its phosphorylation at Thr-170<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11355576' target='_blank'>PMID:11355576</a><BR>c_re147(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7629134' target='_blank'>PMID:7629134</a><BR>c_re174(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re175(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re216(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7799941' target='_blank'>PMID:7799941</a><BR>c_re310(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity activated by its phosphorylation by CAK-complex<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11959850' target='_blank'>PMID:11959850</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/4_5.gif'/> REF=4 <span style='color:red'>FUNC=5</span></p></span>,",
"c_s663": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s663\"]) } catch (e) {}; return false;' title=\"c_s663 1 modifs\">CDKN3</a> <a href='javascript_required.html' onclick='try { show_blog(263); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase inhibitor 3<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDKN3' target='_blank'>HUGO:CDKN3</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1791' target='_blank'>HGNC:1791</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1033' target='_blank'>ENTREZ:1033</a> <a href='http://www.expasy.org/uniprot/Q16667' target='_blank'>UNIPROT:Q16667</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDKN3' target='_blank'>GENECARDS:CDKN3</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1033' target='_blank'>KEGG:1033</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CDKN3.html' target='_blank'>ATLASONC:GC_CDKN3</a> <a href='http://wikipedia.org/wiki/CDKN3' target='_blank'>WIKI:CDKN3</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s663\"]); } catch (e) {}; return false;' title=\"c_s663 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s663\"]); } catch (e) {}; return false;' title=\"c_s663 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>CDKN3=KAP1, Serine and Threonine phosphatase. Is able to dephosphorylate a CDK only if the latter is monomeric, i.e. after degradation of the cyclin.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11355576' target='_blank'>PMID:11355576</a></p><hr><BR><b>Modification:</b><br>CDKN3<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re251:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s663\"]); } catch (e) {}; return false;' title=\"c_s663 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11355576' target='_blank'>PMID:11355576</a><BR></p></span>",
"s778": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]) } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\">CyclinD*</a> <a href='javascript_required.html' onclick='try { show_blog(1764); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin D1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCND1' target='_blank'>HUGO:CCND1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1582' target='_blank'>HGNC:1582</a> <a href='http://www.ncbi.nlm.nih.gov/gene/595' target='_blank'>ENTREZ:595</a> <a href='http://www.expasy.org/uniprot/P24385' target='_blank'>UNIPROT:P24385</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCND1' target='_blank'>GENECARDS:CCND1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68327' target='_blank'>REACTOME:68327</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:595' target='_blank'>KEGG:595</a> <a href='http://atlasgeneticsoncology.org//Genes/BCL1.html' target='_blank'>ATLASONC:BCL1</a> <a href='http://wikipedia.org/wiki/CCND1' target='_blank'>WIKI:CCND1</a> <BR>Cyclin D2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCND2' target='_blank'>HUGO:CCND2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1583' target='_blank'>HGNC:1583</a> <a href='http://www.ncbi.nlm.nih.gov/gene/894' target='_blank'>ENTREZ:894</a> <a href='http://www.expasy.org/uniprot/P30279' target='_blank'>UNIPROT:P30279</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCND2' target='_blank'>GENECARDS:CCND2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68339' target='_blank'>REACTOME:68339</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:894' target='_blank'>KEGG:894</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCND2.html' target='_blank'>ATLASONC:GC_CCND2</a> <a href='http://wikipedia.org/wiki/CCND2' target='_blank'>WIKI:CCND2</a> <BR>Cyclin D3<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCND3' target='_blank'>HUGO:CCND3</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1585' target='_blank'>HGNC:1585</a> <a href='http://www.ncbi.nlm.nih.gov/gene/896' target='_blank'>ENTREZ:896</a> <a href='http://www.expasy.org/uniprot/P30281' target='_blank'>UNIPROT:P30281</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCND3' target='_blank'>GENECARDS:CCND3</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68332' target='_blank'>REACTOME:68332</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCND3.html' target='_blank'>ATLASONC:GC_CCND3</a> <a href='http://wikipedia.org/wiki/CCND3' target='_blank'>WIKI:CCND3</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLIND&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLIND/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s780\", \"s253\"]) } catch (e) {}; return false;' title=\"s780 s253 2 modifs\">CDK4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"s1512\", \"s779\", \"s775\"]) } catch (e) {}; return false;' title=\"c_s1471 s1512 s779 s775 4 modifs\">p21CIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK4:CyclinD*:p21CIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re325:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>,",
"s773": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]) } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\">CyclinD*</a> <a href='javascript_required.html' onclick='try { show_blog(1764); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin D1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCND1' target='_blank'>HUGO:CCND1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1582' target='_blank'>HGNC:1582</a> <a href='http://www.ncbi.nlm.nih.gov/gene/595' target='_blank'>ENTREZ:595</a> <a href='http://www.expasy.org/uniprot/P24385' target='_blank'>UNIPROT:P24385</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCND1' target='_blank'>GENECARDS:CCND1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68327' target='_blank'>REACTOME:68327</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:595' target='_blank'>KEGG:595</a> <a href='http://atlasgeneticsoncology.org//Genes/BCL1.html' target='_blank'>ATLASONC:BCL1</a> <a href='http://wikipedia.org/wiki/CCND1' target='_blank'>WIKI:CCND1</a> <BR>Cyclin D2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCND2' target='_blank'>HUGO:CCND2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1583' target='_blank'>HGNC:1583</a> <a href='http://www.ncbi.nlm.nih.gov/gene/894' target='_blank'>ENTREZ:894</a> <a href='http://www.expasy.org/uniprot/P30279' target='_blank'>UNIPROT:P30279</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCND2' target='_blank'>GENECARDS:CCND2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68339' target='_blank'>REACTOME:68339</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:894' target='_blank'>KEGG:894</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCND2.html' target='_blank'>ATLASONC:GC_CCND2</a> <a href='http://wikipedia.org/wiki/CCND2' target='_blank'>WIKI:CCND2</a> <BR>Cyclin D3<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCND3' target='_blank'>HUGO:CCND3</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1585' target='_blank'>HGNC:1585</a> <a href='http://www.ncbi.nlm.nih.gov/gene/896' target='_blank'>ENTREZ:896</a> <a href='http://www.expasy.org/uniprot/P30281' target='_blank'>UNIPROT:P30281</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCND3' target='_blank'>GENECARDS:CCND3</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68332' target='_blank'>REACTOME:68332</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCND3.html' target='_blank'>ATLASONC:GC_CCND3</a> <a href='http://wikipedia.org/wiki/CCND3' target='_blank'>WIKI:CCND3</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLIND&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLIND/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s774\", \"s250\"]) } catch (e) {}; return false;' title=\"s774 s250 2 modifs\">CDK6</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"s1512\", \"s779\", \"s775\"]) } catch (e) {}; return false;' title=\"c_s1471 s1512 s779 s775 4 modifs\">p21CIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK6:CyclinD*:p21CIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re324:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16775416' target='_blank'>PMID:16775416</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>,",
"s252": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]) } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\">CyclinD*</a> <a href='javascript_required.html' onclick='try { show_blog(1764); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin D1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCND1' target='_blank'>HUGO:CCND1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1582' target='_blank'>HGNC:1582</a> <a href='http://www.ncbi.nlm.nih.gov/gene/595' target='_blank'>ENTREZ:595</a> <a href='http://www.expasy.org/uniprot/P24385' target='_blank'>UNIPROT:P24385</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCND1' target='_blank'>GENECARDS:CCND1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68327' target='_blank'>REACTOME:68327</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:595' target='_blank'>KEGG:595</a> <a href='http://atlasgeneticsoncology.org//Genes/BCL1.html' target='_blank'>ATLASONC:BCL1</a> <a href='http://wikipedia.org/wiki/CCND1' target='_blank'>WIKI:CCND1</a> <BR>Cyclin D2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCND2' target='_blank'>HUGO:CCND2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1583' target='_blank'>HGNC:1583</a> <a href='http://www.ncbi.nlm.nih.gov/gene/894' target='_blank'>ENTREZ:894</a> <a href='http://www.expasy.org/uniprot/P30279' target='_blank'>UNIPROT:P30279</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCND2' target='_blank'>GENECARDS:CCND2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68339' target='_blank'>REACTOME:68339</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:894' target='_blank'>KEGG:894</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCND2.html' target='_blank'>ATLASONC:GC_CCND2</a> <a href='http://wikipedia.org/wiki/CCND2' target='_blank'>WIKI:CCND2</a> <BR>Cyclin D3<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCND3' target='_blank'>HUGO:CCND3</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1585' target='_blank'>HGNC:1585</a> <a href='http://www.ncbi.nlm.nih.gov/gene/896' target='_blank'>ENTREZ:896</a> <a href='http://www.expasy.org/uniprot/P30281' target='_blank'>UNIPROT:P30281</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCND3' target='_blank'>GENECARDS:CCND3</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68332' target='_blank'>REACTOME:68332</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCND3.html' target='_blank'>ATLASONC:GC_CCND3</a> <a href='http://wikipedia.org/wiki/CCND3' target='_blank'>WIKI:CCND3</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLIND&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLIND/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s780\", \"s253\"]) } catch (e) {}; return false;' title=\"s780 s253 2 modifs\">CDK4</a>|Thr172_pho:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"s649\", \"s653\", \"s652\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 s649 s653 s652 5 modifs\">p27KIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK4:CyclinD*:p27KIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re175(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>,",
"s249": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]) } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\">CyclinD*</a> <a href='javascript_required.html' onclick='try { show_blog(1764); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin D1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCND1' target='_blank'>HUGO:CCND1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1582' target='_blank'>HGNC:1582</a> <a href='http://www.ncbi.nlm.nih.gov/gene/595' target='_blank'>ENTREZ:595</a> <a href='http://www.expasy.org/uniprot/P24385' target='_blank'>UNIPROT:P24385</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCND1' target='_blank'>GENECARDS:CCND1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68327' target='_blank'>REACTOME:68327</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:595' target='_blank'>KEGG:595</a> <a href='http://atlasgeneticsoncology.org//Genes/BCL1.html' target='_blank'>ATLASONC:BCL1</a> <a href='http://wikipedia.org/wiki/CCND1' target='_blank'>WIKI:CCND1</a> <BR>Cyclin D2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCND2' target='_blank'>HUGO:CCND2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1583' target='_blank'>HGNC:1583</a> <a href='http://www.ncbi.nlm.nih.gov/gene/894' target='_blank'>ENTREZ:894</a> <a href='http://www.expasy.org/uniprot/P30279' target='_blank'>UNIPROT:P30279</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCND2' target='_blank'>GENECARDS:CCND2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68339' target='_blank'>REACTOME:68339</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:894' target='_blank'>KEGG:894</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCND2.html' target='_blank'>ATLASONC:GC_CCND2</a> <a href='http://wikipedia.org/wiki/CCND2' target='_blank'>WIKI:CCND2</a> <BR>Cyclin D3<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCND3' target='_blank'>HUGO:CCND3</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1585' target='_blank'>HGNC:1585</a> <a href='http://www.ncbi.nlm.nih.gov/gene/896' target='_blank'>ENTREZ:896</a> <a href='http://www.expasy.org/uniprot/P30281' target='_blank'>UNIPROT:P30281</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCND3' target='_blank'>GENECARDS:CCND3</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68332' target='_blank'>REACTOME:68332</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCND3.html' target='_blank'>ATLASONC:GC_CCND3</a> <a href='http://wikipedia.org/wiki/CCND3' target='_blank'>WIKI:CCND3</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLIND&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLIND/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s781\", \"c_s776\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s781 c_s776 c_s725 c_s724 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s774\", \"s250\"]) } catch (e) {}; return false;' title=\"s774 s250 2 modifs\">CDK6</a>|Thr_pho:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"s649\", \"s653\", \"s652\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 s649 s653 s652 5 modifs\">p27KIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK6:CyclinD*:p27KIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re174(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_4.gif'/> REF=5 <span style='color:orange'>FUNC=4</span></p></span>,",
"c_s529": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(1040); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin E1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE1' target='_blank'>HUGO:CCNE1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1589' target='_blank'>HGNC:1589</a> <a href='http://www.ncbi.nlm.nih.gov/gene/898' target='_blank'>ENTREZ:898</a> <a href='http://www.expasy.org/uniprot/P24864' target='_blank'>UNIPROT:P24864</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE1' target='_blank'>GENECARDS:CCNE1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87225' target='_blank'>REACTOME:87225</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:898' target='_blank'>KEGG:898</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE1.html' target='_blank'>ATLASONC:GC_CCNE1</a> <a href='http://wikipedia.org/wiki/CCNE1' target='_blank'>WIKI:CCNE1</a> <BR>Cyclin E2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE2' target='_blank'>HUGO:CCNE2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1590' target='_blank'>HGNC:1590</a> <a href='http://www.ncbi.nlm.nih.gov/gene/9134' target='_blank'>ENTREZ:9134</a> <a href='http://www.expasy.org/uniprot/O96020' target='_blank'>UNIPROT:O96020</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE2' target='_blank'>GENECARDS:CCNE2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87228' target='_blank'>REACTOME:87228</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:9134' target='_blank'>KEGG:9134</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE2.html' target='_blank'>ATLASONC:GC_CCNE2</a> <a href='http://wikipedia.org/wiki/CCNE2' target='_blank'>WIKI:CCNE2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br>CyclinE*|Thr380_pho<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re250:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s529\"]); } catch (e) {}; return false;' title=\"c_s529 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR>c_re252(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s529\"]); } catch (e) {}; return false;' title=\"c_s529 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Degradation via the ubiquitin/proteasome system.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR></p></span>",
"c_s29": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(1040); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin E1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE1' target='_blank'>HUGO:CCNE1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1589' target='_blank'>HGNC:1589</a> <a href='http://www.ncbi.nlm.nih.gov/gene/898' target='_blank'>ENTREZ:898</a> <a href='http://www.expasy.org/uniprot/P24864' target='_blank'>UNIPROT:P24864</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE1' target='_blank'>GENECARDS:CCNE1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87225' target='_blank'>REACTOME:87225</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:898' target='_blank'>KEGG:898</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE1.html' target='_blank'>ATLASONC:GC_CCNE1</a> <a href='http://wikipedia.org/wiki/CCNE1' target='_blank'>WIKI:CCNE1</a> <BR>Cyclin E2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE2' target='_blank'>HUGO:CCNE2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1590' target='_blank'>HGNC:1590</a> <a href='http://www.ncbi.nlm.nih.gov/gene/9134' target='_blank'>ENTREZ:9134</a> <a href='http://www.expasy.org/uniprot/O96020' target='_blank'>UNIPROT:O96020</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE2' target='_blank'>GENECARDS:CCNE2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87228' target='_blank'>REACTOME:87228</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:9134' target='_blank'>KEGG:9134</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE2.html' target='_blank'>ATLASONC:GC_CCNE2</a> <a href='http://wikipedia.org/wiki/CCNE2' target='_blank'>WIKI:CCNE2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br>CyclinE*<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re306:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s29\"]); } catch (e) {}; return false;' title=\"c_s29 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7799941' target='_blank'>PMID:7799941</a><BR></p></span>",
"s1488": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(1040); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin E1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE1' target='_blank'>HUGO:CCNE1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1589' target='_blank'>HGNC:1589</a> <a href='http://www.ncbi.nlm.nih.gov/gene/898' target='_blank'>ENTREZ:898</a> <a href='http://www.expasy.org/uniprot/P24864' target='_blank'>UNIPROT:P24864</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE1' target='_blank'>GENECARDS:CCNE1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87225' target='_blank'>REACTOME:87225</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:898' target='_blank'>KEGG:898</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE1.html' target='_blank'>ATLASONC:GC_CCNE1</a> <a href='http://wikipedia.org/wiki/CCNE1' target='_blank'>WIKI:CCNE1</a> <BR>Cyclin E2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE2' target='_blank'>HUGO:CCNE2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1590' target='_blank'>HGNC:1590</a> <a href='http://www.ncbi.nlm.nih.gov/gene/9134' target='_blank'>ENTREZ:9134</a> <a href='http://www.expasy.org/uniprot/O96020' target='_blank'>UNIPROT:O96020</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE2' target='_blank'>GENECARDS:CCNE2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87228' target='_blank'>REACTOME:87228</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:9134' target='_blank'>KEGG:9134</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE2.html' target='_blank'>ATLASONC:GC_CCNE2</a> <a href='http://wikipedia.org/wiki/CCNE2' target='_blank'>WIKI:CCNE2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s23\", \"s1490\"]) } catch (e) {}; return false;' title=\"c_s23 s1490 2 modifs\">p107*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p107*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re1275:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p></span>,",
"s1483": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(1040); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin E1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE1' target='_blank'>HUGO:CCNE1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1589' target='_blank'>HGNC:1589</a> <a href='http://www.ncbi.nlm.nih.gov/gene/898' target='_blank'>ENTREZ:898</a> <a href='http://www.expasy.org/uniprot/P24864' target='_blank'>UNIPROT:P24864</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE1' target='_blank'>GENECARDS:CCNE1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87225' target='_blank'>REACTOME:87225</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:898' target='_blank'>KEGG:898</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE1.html' target='_blank'>ATLASONC:GC_CCNE1</a> <a href='http://wikipedia.org/wiki/CCNE1' target='_blank'>WIKI:CCNE1</a> <BR>Cyclin E2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE2' target='_blank'>HUGO:CCNE2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1590' target='_blank'>HGNC:1590</a> <a href='http://www.ncbi.nlm.nih.gov/gene/9134' target='_blank'>ENTREZ:9134</a> <a href='http://www.expasy.org/uniprot/O96020' target='_blank'>UNIPROT:O96020</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE2' target='_blank'>GENECARDS:CCNE2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87228' target='_blank'>REACTOME:87228</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:9134' target='_blank'>KEGG:9134</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE2.html' target='_blank'>ATLASONC:GC_CCNE2</a> <a href='http://wikipedia.org/wiki/CCNE2' target='_blank'>WIKI:CCNE2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a>|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re1276(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>p130 binds to and inhibits CYCLINE-CDK2, independantly of its phosphorylation state.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p></span>,",
"s785": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(1040); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin E1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE1' target='_blank'>HUGO:CCNE1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1589' target='_blank'>HGNC:1589</a> <a href='http://www.ncbi.nlm.nih.gov/gene/898' target='_blank'>ENTREZ:898</a> <a href='http://www.expasy.org/uniprot/P24864' target='_blank'>UNIPROT:P24864</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE1' target='_blank'>GENECARDS:CCNE1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87225' target='_blank'>REACTOME:87225</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:898' target='_blank'>KEGG:898</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE1.html' target='_blank'>ATLASONC:GC_CCNE1</a> <a href='http://wikipedia.org/wiki/CCNE1' target='_blank'>WIKI:CCNE1</a> <BR>Cyclin E2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE2' target='_blank'>HUGO:CCNE2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1590' target='_blank'>HGNC:1590</a> <a href='http://www.ncbi.nlm.nih.gov/gene/9134' target='_blank'>ENTREZ:9134</a> <a href='http://www.expasy.org/uniprot/O96020' target='_blank'>UNIPROT:O96020</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE2' target='_blank'>GENECARDS:CCNE2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87228' target='_blank'>REACTOME:87228</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:9134' target='_blank'>KEGG:9134</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE2.html' target='_blank'>ATLASONC:GC_CCNE2</a> <a href='http://wikipedia.org/wiki/CCNE2' target='_blank'>WIKI:CCNE2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"s1512\", \"s779\", \"s775\"]) } catch (e) {}; return false;' title=\"c_s1471 s1512 s779 s775 4 modifs\">p21CIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p21CIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s787\"]); } catch (e) {}; return false;' title=\"c_s787 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s787\"]); } catch (e) {}; return false;' title=\"c_s787 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re327:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s787\"]); } catch (e) {}; return false;' title=\"c_s787 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p></span>,",
"s238": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(1040); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin E1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE1' target='_blank'>HUGO:CCNE1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1589' target='_blank'>HGNC:1589</a> <a href='http://www.ncbi.nlm.nih.gov/gene/898' target='_blank'>ENTREZ:898</a> <a href='http://www.expasy.org/uniprot/P24864' target='_blank'>UNIPROT:P24864</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE1' target='_blank'>GENECARDS:CCNE1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87225' target='_blank'>REACTOME:87225</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:898' target='_blank'>KEGG:898</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE1.html' target='_blank'>ATLASONC:GC_CCNE1</a> <a href='http://wikipedia.org/wiki/CCNE1' target='_blank'>WIKI:CCNE1</a> <BR>Cyclin E2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE2' target='_blank'>HUGO:CCNE2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1590' target='_blank'>HGNC:1590</a> <a href='http://www.ncbi.nlm.nih.gov/gene/9134' target='_blank'>ENTREZ:9134</a> <a href='http://www.expasy.org/uniprot/O96020' target='_blank'>UNIPROT:O96020</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE2' target='_blank'>GENECARDS:CCNE2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87228' target='_blank'>REACTOME:87228</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:9134' target='_blank'>KEGG:9134</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE2.html' target='_blank'>ATLASONC:GC_CCNE2</a> <a href='http://wikipedia.org/wiki/CCNE2' target='_blank'>WIKI:CCNE2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"s649\", \"s653\", \"s652\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 s649 s653 s652 5 modifs\">p27KIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p27KIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re170(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Complex CYCLINE-CDK2 inhibited by its interaction with CKI.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p></span>,",
"s217": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(1040); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin E1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE1' target='_blank'>HUGO:CCNE1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1589' target='_blank'>HGNC:1589</a> <a href='http://www.ncbi.nlm.nih.gov/gene/898' target='_blank'>ENTREZ:898</a> <a href='http://www.expasy.org/uniprot/P24864' target='_blank'>UNIPROT:P24864</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE1' target='_blank'>GENECARDS:CCNE1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87225' target='_blank'>REACTOME:87225</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:898' target='_blank'>KEGG:898</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE1.html' target='_blank'>ATLASONC:GC_CCNE1</a> <a href='http://wikipedia.org/wiki/CCNE1' target='_blank'>WIKI:CCNE1</a> <BR>Cyclin E2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE2' target='_blank'>HUGO:CCNE2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1590' target='_blank'>HGNC:1590</a> <a href='http://www.ncbi.nlm.nih.gov/gene/9134' target='_blank'>ENTREZ:9134</a> <a href='http://www.expasy.org/uniprot/O96020' target='_blank'>UNIPROT:O96020</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE2' target='_blank'>GENECARDS:CCNE2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87228' target='_blank'>REACTOME:87228</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:9134' target='_blank'>KEGG:9134</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE2.html' target='_blank'>ATLASONC:GC_CCNE2</a> <a href='http://wikipedia.org/wiki/CCNE2' target='_blank'>WIKI:CCNE2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Tyr14_pho|Tyr15_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s741\"]); } catch (e) {}; return false;' title=\"c_s741 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s741\"]); } catch (e) {}; return false;' title=\"c_s741 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p></span>,",
"s214": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(1040); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin E1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE1' target='_blank'>HUGO:CCNE1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1589' target='_blank'>HGNC:1589</a> <a href='http://www.ncbi.nlm.nih.gov/gene/898' target='_blank'>ENTREZ:898</a> <a href='http://www.expasy.org/uniprot/P24864' target='_blank'>UNIPROT:P24864</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE1' target='_blank'>GENECARDS:CCNE1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87225' target='_blank'>REACTOME:87225</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:898' target='_blank'>KEGG:898</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE1.html' target='_blank'>ATLASONC:GC_CCNE1</a> <a href='http://wikipedia.org/wiki/CCNE1' target='_blank'>WIKI:CCNE1</a> <BR>Cyclin E2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE2' target='_blank'>HUGO:CCNE2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1590' target='_blank'>HGNC:1590</a> <a href='http://www.ncbi.nlm.nih.gov/gene/9134' target='_blank'>ENTREZ:9134</a> <a href='http://www.expasy.org/uniprot/O96020' target='_blank'>UNIPROT:O96020</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE2' target='_blank'>GENECARDS:CCNE2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87228' target='_blank'>REACTOME:87228</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:9134' target='_blank'>KEGG:9134</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE2.html' target='_blank'>ATLASONC:GC_CCNE2</a> <a href='http://wikipedia.org/wiki/CCNE2' target='_blank'>WIKI:CCNE2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re147(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7629134' target='_blank'>PMID:7629134</a><BR>c_re169(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of p27 by cyclin E/CDK2 at Thr-187 results in targeting p27 for its degradation by proteolysis<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR>c_re248(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Cyclin E phosphorylation by CDK2 at Thr-380.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR>Autophosphorylation of the complex CYCLINE/CDK2 at Thr-380 and Thr-62. Phosphorylation at Thr-380 also by GSK-3B. Two other sites of regulation: Ser-372 et Ser-384<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16131838' target='_blank'>PMID:16131838</a><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR>c_re327:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR>c_re1275:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR>c_re1276(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>p130 binds to and inhibits CYCLINE-CDK2, independantly of its phosphorylation state.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>,",
"s219": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(1040); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin E1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE1' target='_blank'>HUGO:CCNE1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1589' target='_blank'>HGNC:1589</a> <a href='http://www.ncbi.nlm.nih.gov/gene/898' target='_blank'>ENTREZ:898</a> <a href='http://www.expasy.org/uniprot/P24864' target='_blank'>UNIPROT:P24864</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE1' target='_blank'>GENECARDS:CCNE1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87225' target='_blank'>REACTOME:87225</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:898' target='_blank'>KEGG:898</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE1.html' target='_blank'>ATLASONC:GC_CCNE1</a> <a href='http://wikipedia.org/wiki/CCNE1' target='_blank'>WIKI:CCNE1</a> <BR>Cyclin E2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE2' target='_blank'>HUGO:CCNE2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1590' target='_blank'>HGNC:1590</a> <a href='http://www.ncbi.nlm.nih.gov/gene/9134' target='_blank'>ENTREZ:9134</a> <a href='http://www.expasy.org/uniprot/O96020' target='_blank'>UNIPROT:O96020</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE2' target='_blank'>GENECARDS:CCNE2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87228' target='_blank'>REACTOME:87228</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:9134' target='_blank'>KEGG:9134</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE2.html' target='_blank'>ATLASONC:GC_CCNE2</a> <a href='http://wikipedia.org/wiki/CCNE2' target='_blank'>WIKI:CCNE2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>|Thr380_pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s722\"]); } catch (e) {}; return false;' title=\"c_s722 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s722\"]); } catch (e) {}; return false;' title=\"c_s722 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re248(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s722\"]); } catch (e) {}; return false;' title=\"c_s722 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Cyclin E phosphorylation by CDK2 at Thr-380.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR>Autophosphorylation of the complex CYCLINE/CDK2 at Thr-380 and Thr-62. Phosphorylation at Thr-380 also by GSK-3B. Two other sites of regulation: Ser-372 et Ser-384<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16131838' target='_blank'>PMID:16131838</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/1_5.gif'/> REF=1 <span style='color:red'>FUNC=5</span></p></span>,",
"s213": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\">CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(1040); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin E1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE1' target='_blank'>HUGO:CCNE1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1589' target='_blank'>HGNC:1589</a> <a href='http://www.ncbi.nlm.nih.gov/gene/898' target='_blank'>ENTREZ:898</a> <a href='http://www.expasy.org/uniprot/P24864' target='_blank'>UNIPROT:P24864</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE1' target='_blank'>GENECARDS:CCNE1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87225' target='_blank'>REACTOME:87225</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:898' target='_blank'>KEGG:898</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE1.html' target='_blank'>ATLASONC:GC_CCNE1</a> <a href='http://wikipedia.org/wiki/CCNE1' target='_blank'>WIKI:CCNE1</a> <BR>Cyclin E2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNE2' target='_blank'>HUGO:CCNE2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1590' target='_blank'>HGNC:1590</a> <a href='http://www.ncbi.nlm.nih.gov/gene/9134' target='_blank'>ENTREZ:9134</a> <a href='http://www.expasy.org/uniprot/O96020' target='_blank'>UNIPROT:O96020</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNE2' target='_blank'>GENECARDS:CCNE2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87228' target='_blank'>REACTOME:87228</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:9134' target='_blank'>KEGG:9134</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNE2.html' target='_blank'>ATLASONC:GC_CCNE2</a> <a href='http://wikipedia.org/wiki/CCNE2' target='_blank'>WIKI:CCNE2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s529\", \"c_s29\", \"c_s1502\", \"c_s1501\", \"c_s787\", \"c_s742\", \"c_s741\", \"c_s723\", \"c_s722\", \"c_s721\"]); } catch (e) {}; return false;' title=\"c_s529 c_s29 c_s1502 c_s1501 c_s787 c_s742 c_s741 c_s723 c_s722 c_s721 10 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re306:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7799941' target='_blank'>PMID:7799941</a><BR>c_re147(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7629134' target='_blank'>PMID:7629134</a><BR>c_re170(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Complex CYCLINE-CDK2 inhibited by its interaction with CKI.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p></span>,",
"s210": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s749\"]) } catch (e) {}; return false;' title=\"c_s749 1 modifs\">CyclinH*</a> <a href='javascript_required.html' onclick='try { show_blog(1086); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin H<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CCNH' target='_blank'>HUGO:CCNH</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1594' target='_blank'>HGNC:1594</a> <a href='http://www.ncbi.nlm.nih.gov/gene/902' target='_blank'>ENTREZ:902</a> <a href='http://www.expasy.org/uniprot/P51946' target='_blank'>UNIPROT:P51946</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CCNH' target='_blank'>GENECARDS:CCNH</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=88594' target='_blank'>REACTOME:88594</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:902' target='_blank'>KEGG:902</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_CCNH.html' target='_blank'>ATLASONC:GC_CCNH</a> <a href='http://wikipedia.org/wiki/CCNH' target='_blank'>WIKI:CCNH</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINH&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINH/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s209\"]) } catch (e) {}; return false;' title=\"s209 1 modifs\">CDK7</a>|Thr170_pho:<a href='javascript_required.html' onclick='try { show_markers([\"s210\"]) } catch (e) {}; return false;' title=\"s210 1 modifs\">CyclinH*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s211\"]) } catch (e) {}; return false;' title=\"s211 1 modifs\">MNAT1</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK7:CyclinH*:MNAT1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINH&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINH/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re245(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK7 activation by its phosphorylation at Thr-170<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11355576' target='_blank'>PMID:11355576</a><BR>c_re147(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7629134' target='_blank'>PMID:7629134</a><BR>c_re174(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re175(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re216(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7799941' target='_blank'>PMID:7799941</a><BR>c_re310(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity activated by its phosphorylation by CAK-complex<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11959850' target='_blank'>PMID:11959850</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/4_5.gif'/> REF=4 <span style='color:red'>FUNC=5</span></p></span>,",
"s98": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1500\", \"c_s717\"]) } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\">DP1*</a> <a href='javascript_required.html' onclick='try { show_blog(1841); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Transcription factor Dp-1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=TFDP1' target='_blank'>HUGO:TFDP1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=11749' target='_blank'>HGNC:11749</a> <a href='http://www.ncbi.nlm.nih.gov/gene/7027' target='_blank'>ENTREZ:7027</a> <a href='http://www.expasy.org/uniprot/Q14186' target='_blank'>UNIPROT:Q14186</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=TFDP1' target='_blank'>GENECARDS:TFDP1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=103193' target='_blank'>REACTOME:103193</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:7027' target='_blank'>KEGG:7027</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_TFDP1.html' target='_blank'>ATLASONC:GC_TFDP1</a> <a href='http://wikipedia.org/wiki/TFDP1' target='_blank'>WIKI:TFDP1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F1&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F1/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F6&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F6/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s335\", \"s99\"]) } catch (e) {}; return false;' title=\"c_s335 s99 2 modifs\">BAF250*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s98\", \"s117\"]) } catch (e) {}; return false;' title=\"s98 s117 2 modifs\">DP1*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s97\", \"s116\"]) } catch (e) {}; return false;' title=\"s97 s116 2 modifs\">E2F1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s96\", \"s115\"]) } catch (e) {}; return false;' title=\"s96 s115 2 modifs\">RB1</a>|pho|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:BAF250*:DP1*:E2F1:RB1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_4.gif'/> REF=5 <span style='color:orange'>FUNC=4</span></p></span>,",
"s117": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1500\", \"c_s717\"]) } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\">DP1*</a> <a href='javascript_required.html' onclick='try { show_blog(1841); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Transcription factor Dp-1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=TFDP1' target='_blank'>HUGO:TFDP1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=11749' target='_blank'>HGNC:11749</a> <a href='http://www.ncbi.nlm.nih.gov/gene/7027' target='_blank'>ENTREZ:7027</a> <a href='http://www.expasy.org/uniprot/Q14186' target='_blank'>UNIPROT:Q14186</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=TFDP1' target='_blank'>GENECARDS:TFDP1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=103193' target='_blank'>REACTOME:103193</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:7027' target='_blank'>KEGG:7027</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_TFDP1.html' target='_blank'>ATLASONC:GC_TFDP1</a> <a href='http://wikipedia.org/wiki/TFDP1' target='_blank'>WIKI:TFDP1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F1&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F1/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F6&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F6/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s98\", \"s117\"]) } catch (e) {}; return false;' title=\"s98 s117 2 modifs\">DP1*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s97\", \"s116\"]) } catch (e) {}; return false;' title=\"s97 s116 2 modifs\">E2F1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s96\", \"s115\"]) } catch (e) {}; return false;' title=\"s96 s115 2 modifs\">RB1</a>|pho|pho|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP1*:E2F1:RB1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F1&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F1/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR>c_re291:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8380224' target='_blank'>PMID:8380224</a>; <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>; <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10773440' target='_blank'>PMID:10773440</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/3_5.gif'/> REF=3 <span style='color:red'>FUNC=5</span></p></span>,",
"s305": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\">DP2*</a> <a href='javascript_required.html' onclick='try { show_blog(1832); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Transcription factor Dp-2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=TFDP2' target='_blank'>HUGO:TFDP2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=11751' target='_blank'>HGNC:11751</a> <a href='http://www.ncbi.nlm.nih.gov/gene/7029' target='_blank'>ENTREZ:7029</a> <a href='http://www.expasy.org/uniprot/Q14188' target='_blank'>UNIPROT:Q14188</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=TFDP2' target='_blank'>GENECARDS:TFDP2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=103195' target='_blank'>REACTOME:103195</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:7029' target='_blank'>KEGG:7029</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_TFDP2.html' target='_blank'>ATLASONC:GC_TFDP2</a> <a href='http://wikipedia.org/wiki/TFDP2' target='_blank'>WIKI:TFDP2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F6&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F6/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s305\", \"s308\"]) } catch (e) {}; return false;' title=\"s305 s308 2 modifs\">DP2*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s303\", \"s310\"]) } catch (e) {}; return false;' title=\"s303 s310 2 modifs\">E2F4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s304\", \"s309\"]) } catch (e) {}; return false;' title=\"s304 s309 2 modifs\">HDAC1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s621\", \"s622\"]) } catch (e) {}; return false;' title=\"s621 s622 2 modifs\">SIN3B</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s306\", \"s307\"]) } catch (e) {}; return false;' title=\"s306 s307 2 modifs\">SUV39H1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP2*:E2F4:HDAC1:SIN3B:SUV39H1:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re288(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>HDAC1 and Sin3B associate to the promoteurs via E2F4 and p130/p107<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11959842' target='_blank'>PMID:11959842</a><BR>HDAC1 and SUV39H1 associate to the promoteurs via E2F4 and p130/p107<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/3_4.gif'/> REF=3 <span style='color:orange'>FUNC=4</span></p></span>,",
"s308": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\">DP2*</a> <a href='javascript_required.html' onclick='try { show_blog(1832); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Transcription factor Dp-2<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=TFDP2' target='_blank'>HUGO:TFDP2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=11751' target='_blank'>HGNC:11751</a> <a href='http://www.ncbi.nlm.nih.gov/gene/7029' target='_blank'>ENTREZ:7029</a> <a href='http://www.expasy.org/uniprot/Q14188' target='_blank'>UNIPROT:Q14188</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=TFDP2' target='_blank'>GENECARDS:TFDP2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=103195' target='_blank'>REACTOME:103195</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:7029' target='_blank'>KEGG:7029</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_TFDP2.html' target='_blank'>ATLASONC:GC_TFDP2</a> <a href='http://wikipedia.org/wiki/TFDP2' target='_blank'>WIKI:TFDP2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F6&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F6/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s305\", \"s308\"]) } catch (e) {}; return false;' title=\"s305 s308 2 modifs\">DP2*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s303\", \"s310\"]) } catch (e) {}; return false;' title=\"s303 s310 2 modifs\">E2F4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s304\", \"s309\"]) } catch (e) {}; return false;' title=\"s304 s309 2 modifs\">HDAC1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s621\", \"s622\"]) } catch (e) {}; return false;' title=\"s621 s622 2 modifs\">SIN3B</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s306\", \"s307\"]) } catch (e) {}; return false;' title=\"s306 s307 2 modifs\">SUV39H1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a>|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP2*:E2F4:HDAC1:SIN3B:SUV39H1:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re290(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_4.gif'/> REF=2 <span style='color:orange'>FUNC=4</span></p></span>,",
"s97": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1500\", \"c_s717\"]) } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\">E2F1</a> <a href='javascript_required.html' onclick='try { show_blog(3904); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>E2F transcription factor 1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=E2F1' target='_blank'>HUGO:E2F1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=3113' target='_blank'>HGNC:3113</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1869' target='_blank'>ENTREZ:1869</a> <a href='http://www.expasy.org/uniprot/Q01094' target='_blank'>UNIPROT:Q01094</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=E2F1' target='_blank'>GENECARDS:E2F1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=89561' target='_blank'>REACTOME:89561</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1869' target='_blank'>KEGG:1869</a> <a href='http://atlasgeneticsoncology.org//Genes/E2F1ID40382ch20q11.html' target='_blank'>ATLASONC:E2F1ID40382ch20q11</a> <a href='http://wikipedia.org/wiki/E2F1' target='_blank'>WIKI:E2F1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_S_CHECKPOINT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_S_CHECKPOINT/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F1&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F1/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_ENTRY&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/APOPTOSIS_ENTRY/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;WNT_CANONICAL&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/WNT_CANONICAL/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s335\", \"s99\"]) } catch (e) {}; return false;' title=\"c_s335 s99 2 modifs\">BAF250*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s98\", \"s117\"]) } catch (e) {}; return false;' title=\"s98 s117 2 modifs\">DP1*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s97\", \"s116\"]) } catch (e) {}; return false;' title=\"s97 s116 2 modifs\">E2F1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s96\", \"s115\"]) } catch (e) {}; return false;' title=\"s96 s115 2 modifs\">RB1</a>|pho|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:BAF250*:DP1*:E2F1:RB1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_4.gif'/> REF=5 <span style='color:orange'>FUNC=4</span></p></span>,",
"s116": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1500\", \"c_s717\"]) } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\">E2F1</a> <a href='javascript_required.html' onclick='try { show_blog(3904); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>E2F transcription factor 1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=E2F1' target='_blank'>HUGO:E2F1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=3113' target='_blank'>HGNC:3113</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1869' target='_blank'>ENTREZ:1869</a> <a href='http://www.expasy.org/uniprot/Q01094' target='_blank'>UNIPROT:Q01094</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=E2F1' target='_blank'>GENECARDS:E2F1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=89561' target='_blank'>REACTOME:89561</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1869' target='_blank'>KEGG:1869</a> <a href='http://atlasgeneticsoncology.org//Genes/E2F1ID40382ch20q11.html' target='_blank'>ATLASONC:E2F1ID40382ch20q11</a> <a href='http://wikipedia.org/wiki/E2F1' target='_blank'>WIKI:E2F1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_S_CHECKPOINT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_S_CHECKPOINT/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F1&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F1/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_ENTRY&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/APOPTOSIS_ENTRY/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;WNT_CANONICAL&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/WNT_CANONICAL/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s98\", \"s117\"]) } catch (e) {}; return false;' title=\"s98 s117 2 modifs\">DP1*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s97\", \"s116\"]) } catch (e) {}; return false;' title=\"s97 s116 2 modifs\">E2F1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s96\", \"s115\"]) } catch (e) {}; return false;' title=\"s96 s115 2 modifs\">RB1</a>|pho|pho|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP1*:E2F1:RB1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F1&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F1/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR>c_re291:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8380224' target='_blank'>PMID:8380224</a>; <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>; <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10773440' target='_blank'>PMID:10773440</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/3_5.gif'/> REF=3 <span style='color:red'>FUNC=5</span></p></span>,",
"s303": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\">E2F4</a> <a href='javascript_required.html' onclick='try { show_blog(1498); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>E2F transcription factor 4, P107/P130-binding<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=E2F4' target='_blank'>HUGO:E2F4</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=3118' target='_blank'>HGNC:3118</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1874' target='_blank'>ENTREZ:1874</a> <a href='http://www.expasy.org/uniprot/Q16254' target='_blank'>UNIPROT:Q16254</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=E2F4' target='_blank'>GENECARDS:E2F4</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68663' target='_blank'>REACTOME:68663</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1874' target='_blank'>KEGG:1874</a> <a href='http://atlasgeneticsoncology.org//Genes/E2F4ID40385ch16q22.html' target='_blank'>ATLASONC:E2F4ID40385ch16q22</a> <a href='http://wikipedia.org/wiki/E2F4' target='_blank'>WIKI:E2F4</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s305\", \"s308\"]) } catch (e) {}; return false;' title=\"s305 s308 2 modifs\">DP2*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s303\", \"s310\"]) } catch (e) {}; return false;' title=\"s303 s310 2 modifs\">E2F4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s304\", \"s309\"]) } catch (e) {}; return false;' title=\"s304 s309 2 modifs\">HDAC1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s621\", \"s622\"]) } catch (e) {}; return false;' title=\"s621 s622 2 modifs\">SIN3B</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s306\", \"s307\"]) } catch (e) {}; return false;' title=\"s306 s307 2 modifs\">SUV39H1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP2*:E2F4:HDAC1:SIN3B:SUV39H1:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re288(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>HDAC1 and Sin3B associate to the promoteurs via E2F4 and p130/p107<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11959842' target='_blank'>PMID:11959842</a><BR>HDAC1 and SUV39H1 associate to the promoteurs via E2F4 and p130/p107<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/3_4.gif'/> REF=3 <span style='color:orange'>FUNC=4</span></p></span>,",
"s310": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\">E2F4</a> <a href='javascript_required.html' onclick='try { show_blog(1498); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>E2F transcription factor 4, P107/P130-binding<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=E2F4' target='_blank'>HUGO:E2F4</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=3118' target='_blank'>HGNC:3118</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1874' target='_blank'>ENTREZ:1874</a> <a href='http://www.expasy.org/uniprot/Q16254' target='_blank'>UNIPROT:Q16254</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=E2F4' target='_blank'>GENECARDS:E2F4</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=68663' target='_blank'>REACTOME:68663</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1874' target='_blank'>KEGG:1874</a> <a href='http://atlasgeneticsoncology.org//Genes/E2F4ID40385ch16q22.html' target='_blank'>ATLASONC:E2F4ID40385ch16q22</a> <a href='http://wikipedia.org/wiki/E2F4' target='_blank'>WIKI:E2F4</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s305\", \"s308\"]) } catch (e) {}; return false;' title=\"s305 s308 2 modifs\">DP2*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s303\", \"s310\"]) } catch (e) {}; return false;' title=\"s303 s310 2 modifs\">E2F4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s304\", \"s309\"]) } catch (e) {}; return false;' title=\"s304 s309 2 modifs\">HDAC1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s621\", \"s622\"]) } catch (e) {}; return false;' title=\"s621 s622 2 modifs\">SIN3B</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s306\", \"s307\"]) } catch (e) {}; return false;' title=\"s306 s307 2 modifs\">SUV39H1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a>|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP2*:E2F4:HDAC1:SIN3B:SUV39H1:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re290(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_4.gif'/> REF=2 <span style='color:orange'>FUNC=4</span></p></span>,",
"c_s419": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s419\"]) } catch (e) {}; return false;' title=\"c_s419 1 modifs\">GSK3_beta_*</a> <a href='javascript_required.html' onclick='try { show_blog(4000); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Glycogen synthase kinase 3 beta<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=GSK3B' target='_blank'>HUGO:GSK3B</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=4617' target='_blank'>HGNC:4617</a> <a href='http://www.ncbi.nlm.nih.gov/gene/2932' target='_blank'>ENTREZ:2932</a> <a href='http://www.expasy.org/uniprot/P49841' target='_blank'>UNIPROT:P49841</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=GSK3B' target='_blank'>GENECARDS:GSK3B</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=404223' target='_blank'>REACTOME:404223</a> <a href='http://atlasgeneticsoncology.org//Genes/GSK3BID40761ch3q13.html' target='_blank'>ATLASONC:GSK3BID40761ch3q13</a> <a href='http://wikipedia.org/wiki/GSK3B' target='_blank'>WIKI:GSK3B</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/AKT_MTOR/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;MOMP_REGULATION&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/MOMP_REGULATION/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLIND&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLIND/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;HEDGEHOG&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/HEDGEHOG/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;MAPK&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/MAPK/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;WNT_CANONICAL&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/WNT_CANONICAL/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br>GSK3_beta_*<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re155:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a><BR>c_re186:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16732330' target='_blank'>PMID:16732330</a><BR>c_re248(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s419\"]); } catch (e) {}; return false;' title=\"c_s419 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Cyclin E phosphorylation by CDK2 at Thr-380.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR>Autophosphorylation of the complex CYCLINE/CDK2 at Thr-380 and Thr-62. Phosphorylation at Thr-380 also by GSK-3B. Two other sites of regulation: Ser-372 et Ser-384<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16131838' target='_blank'>PMID:16131838</a><BR></p></span>",
"s304": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\">HDAC1</a> <a href='javascript_required.html' onclick='try { show_blog(4121); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Histone deacetylase 1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=HDAC1' target='_blank'>HUGO:HDAC1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=4852' target='_blank'>HGNC:4852</a> <a href='http://www.ncbi.nlm.nih.gov/gene/3065' target='_blank'>ENTREZ:3065</a> <a href='http://www.expasy.org/uniprot/Q13547' target='_blank'>UNIPROT:Q13547</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=HDAC1' target='_blank'>GENECARDS:HDAC1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=56408' target='_blank'>REACTOME:56408</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:3065' target='_blank'>KEGG:3065</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_HDAC1.html' target='_blank'>ATLASONC:GC_HDAC1</a> <a href='http://wikipedia.org/wiki/HDAC1' target='_blank'>WIKI:HDAC1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F1&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F1/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;HEDGEHOG&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/HEDGEHOG/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s305\", \"s308\"]) } catch (e) {}; return false;' title=\"s305 s308 2 modifs\">DP2*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s303\", \"s310\"]) } catch (e) {}; return false;' title=\"s303 s310 2 modifs\">E2F4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s304\", \"s309\"]) } catch (e) {}; return false;' title=\"s304 s309 2 modifs\">HDAC1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s621\", \"s622\"]) } catch (e) {}; return false;' title=\"s621 s622 2 modifs\">SIN3B</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s306\", \"s307\"]) } catch (e) {}; return false;' title=\"s306 s307 2 modifs\">SUV39H1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP2*:E2F4:HDAC1:SIN3B:SUV39H1:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re288(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>HDAC1 and Sin3B associate to the promoteurs via E2F4 and p130/p107<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11959842' target='_blank'>PMID:11959842</a><BR>HDAC1 and SUV39H1 associate to the promoteurs via E2F4 and p130/p107<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/3_4.gif'/> REF=3 <span style='color:orange'>FUNC=4</span></p></span>,",
"s309": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\">HDAC1</a> <a href='javascript_required.html' onclick='try { show_blog(4121); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Histone deacetylase 1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=HDAC1' target='_blank'>HUGO:HDAC1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=4852' target='_blank'>HGNC:4852</a> <a href='http://www.ncbi.nlm.nih.gov/gene/3065' target='_blank'>ENTREZ:3065</a> <a href='http://www.expasy.org/uniprot/Q13547' target='_blank'>UNIPROT:Q13547</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=HDAC1' target='_blank'>GENECARDS:HDAC1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=56408' target='_blank'>REACTOME:56408</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:3065' target='_blank'>KEGG:3065</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_HDAC1.html' target='_blank'>ATLASONC:GC_HDAC1</a> <a href='http://wikipedia.org/wiki/HDAC1' target='_blank'>WIKI:HDAC1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F1&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F1/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;HEDGEHOG&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/HEDGEHOG/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s305\", \"s308\"]) } catch (e) {}; return false;' title=\"s305 s308 2 modifs\">DP2*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s303\", \"s310\"]) } catch (e) {}; return false;' title=\"s303 s310 2 modifs\">E2F4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s304\", \"s309\"]) } catch (e) {}; return false;' title=\"s304 s309 2 modifs\">HDAC1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s621\", \"s622\"]) } catch (e) {}; return false;' title=\"s621 s622 2 modifs\">SIN3B</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s306\", \"s307\"]) } catch (e) {}; return false;' title=\"s306 s307 2 modifs\">SUV39H1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a>|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP2*:E2F4:HDAC1:SIN3B:SUV39H1:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re290(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_4.gif'/> REF=2 <span style='color:orange'>FUNC=4</span></p></span>,",
"s211": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s749\"]) } catch (e) {}; return false;' title=\"c_s749 1 modifs\">MNAT1</a> <a href='javascript_required.html' onclick='try { show_blog(1092); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=MNAT1' target='_blank'>HUGO:MNAT1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=7181' target='_blank'>HGNC:7181</a> <a href='http://www.ncbi.nlm.nih.gov/gene/4331' target='_blank'>ENTREZ:4331</a> <a href='http://www.expasy.org/uniprot/P51948' target='_blank'>UNIPROT:P51948</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=MNAT1' target='_blank'>GENECARDS:MNAT1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=69677' target='_blank'>REACTOME:69677</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:4331' target='_blank'>KEGG:4331</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_MNAT1.html' target='_blank'>ATLASONC:GC_MNAT1</a> <a href='http://wikipedia.org/wiki/MNAT1' target='_blank'>WIKI:MNAT1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;NER&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/NER/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINH&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINH/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s209\"]) } catch (e) {}; return false;' title=\"s209 1 modifs\">CDK7</a>|Thr170_pho:<a href='javascript_required.html' onclick='try { show_markers([\"s210\"]) } catch (e) {}; return false;' title=\"s210 1 modifs\">CyclinH*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s211\"]) } catch (e) {}; return false;' title=\"s211 1 modifs\">MNAT1</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK7:CyclinH*:MNAT1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINH&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINH/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re245(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK7 activation by its phosphorylation at Thr-170<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11355576' target='_blank'>PMID:11355576</a><BR>c_re147(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7629134' target='_blank'>PMID:7629134</a><BR>c_re174(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re175(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re216(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7799941' target='_blank'>PMID:7799941</a><BR>c_re310(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity activated by its phosphorylation by CAK-complex<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11959850' target='_blank'>PMID:11959850</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/4_5.gif'/> REF=4 <span style='color:red'>FUNC=5</span></p></span>,",
"s96": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1500\", \"c_s717\"]) } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\">RB1</a> <a href='javascript_required.html' onclick='try { show_blog(608); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Retinoblastoma 1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=RB1' target='_blank'>HUGO:RB1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=9884' target='_blank'>HGNC:9884</a> <a href='http://www.ncbi.nlm.nih.gov/gene/5925' target='_blank'>ENTREZ:5925</a> <a href='http://www.expasy.org/uniprot/P06400' target='_blank'>UNIPROT:P06400</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=RB1' target='_blank'>GENECARDS:RB1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=62886' target='_blank'>REACTOME:62886</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:5925' target='_blank'>KEGG:5925</a> <a href='http://atlasgeneticsoncology.org//Genes/RB1ID90.html' target='_blank'>ATLASONC:RB1ID90</a> <a href='http://wikipedia.org/wiki/RB1' target='_blank'>WIKI:RB1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_S_CHECKPOINT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_S_CHECKPOINT/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F1&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F1/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>Inhibition of E2F binding by phosphorylation at several of the 7 C-terminal sites or at one of the two serines 807 and 811.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s335\", \"s99\"]) } catch (e) {}; return false;' title=\"c_s335 s99 2 modifs\">BAF250*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s98\", \"s117\"]) } catch (e) {}; return false;' title=\"s98 s117 2 modifs\">DP1*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s97\", \"s116\"]) } catch (e) {}; return false;' title=\"s97 s116 2 modifs\">E2F1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s96\", \"s115\"]) } catch (e) {}; return false;' title=\"s96 s115 2 modifs\">RB1</a>|pho|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:BAF250*:DP1*:E2F1:RB1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_4.gif'/> REF=5 <span style='color:orange'>FUNC=4</span></p></span>,",
"s115": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1500\", \"c_s717\"]) } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\">RB1</a> <a href='javascript_required.html' onclick='try { show_blog(608); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Retinoblastoma 1<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=RB1' target='_blank'>HUGO:RB1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=9884' target='_blank'>HGNC:9884</a> <a href='http://www.ncbi.nlm.nih.gov/gene/5925' target='_blank'>ENTREZ:5925</a> <a href='http://www.expasy.org/uniprot/P06400' target='_blank'>UNIPROT:P06400</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=RB1' target='_blank'>GENECARDS:RB1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=62886' target='_blank'>REACTOME:62886</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:5925' target='_blank'>KEGG:5925</a> <a href='http://atlasgeneticsoncology.org//Genes/RB1ID90.html' target='_blank'>ATLASONC:RB1ID90</a> <a href='http://wikipedia.org/wiki/RB1' target='_blank'>WIKI:RB1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_S_CHECKPOINT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_S_CHECKPOINT/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F1&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F1/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s1500\", \"c_s717\"]); } catch (e) {}; return false;' title=\"c_s1500 c_s717 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>Inhibition of E2F binding by phosphorylation at several of the 7 C-terminal sites or at one of the two serines 807 and 811.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s98\", \"s117\"]) } catch (e) {}; return false;' title=\"s98 s117 2 modifs\">DP1*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s97\", \"s116\"]) } catch (e) {}; return false;' title=\"s97 s116 2 modifs\">E2F1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s96\", \"s115\"]) } catch (e) {}; return false;' title=\"s96 s115 2 modifs\">RB1</a>|pho|pho|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP1*:E2F1:RB1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F1&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F1/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR>c_re291:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8380224' target='_blank'>PMID:8380224</a>; <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>; <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10773440' target='_blank'>PMID:10773440</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/3_5.gif'/> REF=3 <span style='color:red'>FUNC=5</span></p></span>,",
"s621": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\">SIN3B</a> <a href='javascript_required.html' onclick='try { show_blog(1838); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>SIN3 homolog B, transcription regulator (yeast)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=SIN3B' target='_blank'>HUGO:SIN3B</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=19354' target='_blank'>HGNC:19354</a> <a href='http://www.ncbi.nlm.nih.gov/gene/23309' target='_blank'>ENTREZ:23309</a> <a href='http://www.expasy.org/uniprot/O75182' target='_blank'>UNIPROT:O75182</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=SIN3B' target='_blank'>GENECARDS:SIN3B</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=101855' target='_blank'>REACTOME:101855</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_SIN3B.html' target='_blank'>ATLASONC:GC_SIN3B</a> <a href='http://wikipedia.org/wiki/SIN3B' target='_blank'>WIKI:SIN3B</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F6&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F6/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s305\", \"s308\"]) } catch (e) {}; return false;' title=\"s305 s308 2 modifs\">DP2*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s303\", \"s310\"]) } catch (e) {}; return false;' title=\"s303 s310 2 modifs\">E2F4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s304\", \"s309\"]) } catch (e) {}; return false;' title=\"s304 s309 2 modifs\">HDAC1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s621\", \"s622\"]) } catch (e) {}; return false;' title=\"s621 s622 2 modifs\">SIN3B</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s306\", \"s307\"]) } catch (e) {}; return false;' title=\"s306 s307 2 modifs\">SUV39H1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP2*:E2F4:HDAC1:SIN3B:SUV39H1:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re288(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>HDAC1 and Sin3B associate to the promoteurs via E2F4 and p130/p107<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11959842' target='_blank'>PMID:11959842</a><BR>HDAC1 and SUV39H1 associate to the promoteurs via E2F4 and p130/p107<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/3_4.gif'/> REF=3 <span style='color:orange'>FUNC=4</span></p></span>,",
"s622": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\">SIN3B</a> <a href='javascript_required.html' onclick='try { show_blog(1838); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>SIN3 homolog B, transcription regulator (yeast)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=SIN3B' target='_blank'>HUGO:SIN3B</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=19354' target='_blank'>HGNC:19354</a> <a href='http://www.ncbi.nlm.nih.gov/gene/23309' target='_blank'>ENTREZ:23309</a> <a href='http://www.expasy.org/uniprot/O75182' target='_blank'>UNIPROT:O75182</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=SIN3B' target='_blank'>GENECARDS:SIN3B</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=101855' target='_blank'>REACTOME:101855</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_SIN3B.html' target='_blank'>ATLASONC:GC_SIN3B</a> <a href='http://wikipedia.org/wiki/SIN3B' target='_blank'>WIKI:SIN3B</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F6&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F6/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s305\", \"s308\"]) } catch (e) {}; return false;' title=\"s305 s308 2 modifs\">DP2*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s303\", \"s310\"]) } catch (e) {}; return false;' title=\"s303 s310 2 modifs\">E2F4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s304\", \"s309\"]) } catch (e) {}; return false;' title=\"s304 s309 2 modifs\">HDAC1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s621\", \"s622\"]) } catch (e) {}; return false;' title=\"s621 s622 2 modifs\">SIN3B</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s306\", \"s307\"]) } catch (e) {}; return false;' title=\"s306 s307 2 modifs\">SUV39H1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a>|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP2*:E2F4:HDAC1:SIN3B:SUV39H1:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re290(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_4.gif'/> REF=2 <span style='color:orange'>FUNC=4</span></p></span>,",
"s306": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\">SUV39H1</a> <a href='javascript_required.html' onclick='try { show_blog(1888); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Suppressor of variegation 3-9 homolog 1 (Drosophila)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=SUV39H1' target='_blank'>HUGO:SUV39H1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=11479' target='_blank'>HGNC:11479</a> <a href='http://www.ncbi.nlm.nih.gov/gene/6839' target='_blank'>ENTREZ:6839</a> <a href='http://www.expasy.org/uniprot/O43463' target='_blank'>UNIPROT:O43463</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=SUV39H1' target='_blank'>GENECARDS:SUV39H1</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:6839' target='_blank'>KEGG:6839</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_SUV39H1.html' target='_blank'>ATLASONC:GC_SUV39H1</a> <a href='http://wikipedia.org/wiki/SUV39H1' target='_blank'>WIKI:SUV39H1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s305\", \"s308\"]) } catch (e) {}; return false;' title=\"s305 s308 2 modifs\">DP2*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s303\", \"s310\"]) } catch (e) {}; return false;' title=\"s303 s310 2 modifs\">E2F4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s304\", \"s309\"]) } catch (e) {}; return false;' title=\"s304 s309 2 modifs\">HDAC1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s621\", \"s622\"]) } catch (e) {}; return false;' title=\"s621 s622 2 modifs\">SIN3B</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s306\", \"s307\"]) } catch (e) {}; return false;' title=\"s306 s307 2 modifs\">SUV39H1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP2*:E2F4:HDAC1:SIN3B:SUV39H1:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re288(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>HDAC1 and Sin3B associate to the promoteurs via E2F4 and p130/p107<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11959842' target='_blank'>PMID:11959842</a><BR>HDAC1 and SUV39H1 associate to the promoteurs via E2F4 and p130/p107<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/3_4.gif'/> REF=3 <span style='color:orange'>FUNC=4</span></p></span>,",
"s307": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\">SUV39H1</a> <a href='javascript_required.html' onclick='try { show_blog(1888); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Suppressor of variegation 3-9 homolog 1 (Drosophila)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=SUV39H1' target='_blank'>HUGO:SUV39H1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=11479' target='_blank'>HGNC:11479</a> <a href='http://www.ncbi.nlm.nih.gov/gene/6839' target='_blank'>ENTREZ:6839</a> <a href='http://www.expasy.org/uniprot/O43463' target='_blank'>UNIPROT:O43463</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=SUV39H1' target='_blank'>GENECARDS:SUV39H1</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:6839' target='_blank'>KEGG:6839</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_SUV39H1.html' target='_blank'>ATLASONC:GC_SUV39H1</a> <a href='http://wikipedia.org/wiki/SUV39H1' target='_blank'>WIKI:SUV39H1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s691 c_s690 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s305\", \"s308\"]) } catch (e) {}; return false;' title=\"s305 s308 2 modifs\">DP2*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s303\", \"s310\"]) } catch (e) {}; return false;' title=\"s303 s310 2 modifs\">E2F4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s304\", \"s309\"]) } catch (e) {}; return false;' title=\"s304 s309 2 modifs\">HDAC1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s621\", \"s622\"]) } catch (e) {}; return false;' title=\"s621 s622 2 modifs\">SIN3B</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s306\", \"s307\"]) } catch (e) {}; return false;' title=\"s306 s307 2 modifs\">SUV39H1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a>|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP2*:E2F4:HDAC1:SIN3B:SUV39H1:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re290(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_4.gif'/> REF=2 <span style='color:orange'>FUNC=4</span></p></span>,",
"c_s411": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s411\"]) } catch (e) {}; return false;' title=\"c_s411 1 modifs\">WEE1</a> <a href='javascript_required.html' onclick='try { show_blog(1737); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>WEE1 homolog (S. pombe)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=WEE1' target='_blank'>HUGO:WEE1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=12761' target='_blank'>HGNC:12761</a> <a href='http://www.ncbi.nlm.nih.gov/gene/7465' target='_blank'>ENTREZ:7465</a> <a href='http://www.expasy.org/uniprot/P30291' target='_blank'>UNIPROT:P30291</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=WEE1' target='_blank'>GENECARDS:WEE1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=104871' target='_blank'>REACTOME:104871</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:7465' target='_blank'>KEGG:7465</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_WEE1.html' target='_blank'>ATLASONC:GC_WEE1</a> <a href='http://wikipedia.org/wiki/WEE1' target='_blank'>WIKI:WEE1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s411\"]); } catch (e) {}; return false;' title=\"c_s411 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s411\"]); } catch (e) {}; return false;' title=\"c_s411 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s411\"]); } catch (e) {}; return false;' title=\"c_s411 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s411\"]); } catch (e) {}; return false;' title=\"c_s411 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s411\"]); } catch (e) {}; return false;' title=\"c_s411 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G2_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G2_CC_PHASE/index.html\", [\"c_s411\"]); } catch (e) {}; return false;' title=\"c_s411 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s411\"]); } catch (e) {}; return false;' title=\"c_s411 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;WEE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/WEE/index.html\", [\"c_s411\"]); } catch (e) {}; return false;' title=\"c_s411 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br>WEE1<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re195(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s411\"]); } catch (e) {}; return false;' title=\"c_s411 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>phosphorylation and inactivation of Wee1 kinase<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8515817' target='_blank'>PMID:8515817</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15070733' target='_blank'>PMID:15070733</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7681363' target='_blank'>PMID:7681363</a> (yeast)<BR>Cyclin B phosphorylates Myt1 in vitro<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9268380' target='_blank'>PMID:9268380</a><BR>c_re218(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s411\"]); } catch (e) {}; return false;' title=\"c_s411 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDC2 phosphorylation at Tyr15 by WEE1, only when CDC2 is bound to a cyclin.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a><BR>WEE1 allows CDC2 to stay in an inactive state after its translocation during G2.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10373560' target='_blank'>PMID:10373560</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8348613' target='_blank'>PMID:8348613</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9001210' target='_blank'>PMID:9001210</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=1384126' target='_blank'>PMID:1384126</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15037762' target='_blank'>PMID:15037762</a><BR>c_re232(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s411\"]); } catch (e) {}; return false;' title=\"c_s411 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>WEE1 allows CDC2 to stay in an inactive state after its translocation in late G2<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10373560' target='_blank'>PMID:10373560</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8348613' target='_blank'>PMID:8348613</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9001210' target='_blank'>PMID:9001210</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15037762' target='_blank'>PMID:15037762</a><BR></p></span>",
"c_s23": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s23\", \"c_s1502\"]) } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\">p107*</a> <a href='javascript_required.html' onclick='try { show_blog(1738); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Retinoblastoma-like 1 (p107)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=RBL1' target='_blank'>HUGO:RBL1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=9893' target='_blank'>HGNC:9893</a> <a href='http://www.ncbi.nlm.nih.gov/gene/5933' target='_blank'>ENTREZ:5933</a> <a href='http://www.expasy.org/uniprot/P28749' target='_blank'>UNIPROT:P28749</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=RBL1' target='_blank'>GENECARDS:RBL1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=62848' target='_blank'>REACTOME:62848</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:5933' target='_blank'>KEGG:5933</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_RBL1.html' target='_blank'>ATLASONC:GC_RBL1</a> <a href='http://wikipedia.org/wiki/RBL1' target='_blank'>WIKI:RBL1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_S_CHECKPOINT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_S_CHECKPOINT/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>More present in proliferating cells.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15838516' target='_blank'>PMID:15838516</a><BR>3 phosphorylation sites that are CDK-dependants (CYCLIND-CDK4/6): T369, S650, S964.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>10 phosphorylation sites conserved in p130.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11157749' target='_blank'>PMID:11157749</a></p><hr><BR><b>Modification:</b><br>p107*<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re91:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s23\"]); } catch (e) {}; return false;' title=\"c_s23 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15231644' target='_blank'>PMID:15231644</a><BR>c_re1273:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s23\"]); } catch (e) {}; return false;' title=\"c_s23 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p></span>",
"s1490": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s23\", \"c_s1502\"]) } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\">p107*</a> <a href='javascript_required.html' onclick='try { show_blog(1738); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Retinoblastoma-like 1 (p107)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=RBL1' target='_blank'>HUGO:RBL1</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=9893' target='_blank'>HGNC:9893</a> <a href='http://www.ncbi.nlm.nih.gov/gene/5933' target='_blank'>ENTREZ:5933</a> <a href='http://www.expasy.org/uniprot/P28749' target='_blank'>UNIPROT:P28749</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=RBL1' target='_blank'>GENECARDS:RBL1</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=62848' target='_blank'>REACTOME:62848</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:5933' target='_blank'>KEGG:5933</a> <a href='http://atlasgeneticsoncology.org//Genes/GC_RBL1.html' target='_blank'>ATLASONC:GC_RBL1</a> <a href='http://wikipedia.org/wiki/RBL1' target='_blank'>WIKI:RBL1</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_S_CHECKPOINT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_S_CHECKPOINT/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;G1_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/G1_CC_PHASE/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;DNA repair&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/master/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;S_CC_PHASE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../dnarepair/S_CC_PHASE/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s23\", \"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s23 c_s1502 2 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>More present in proliferating cells.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15838516' target='_blank'>PMID:15838516</a><BR>3 phosphorylation sites that are CDK-dependants (CYCLIND-CDK4/6): T369, S650, S964.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>10 phosphorylation sites conserved in p130.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11157749' target='_blank'>PMID:11157749</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s23\", \"s1490\"]) } catch (e) {}; return false;' title=\"c_s23 s1490 2 modifs\">p107*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p107*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re1275:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p></span>,",
"c_s3": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\">p130*</a> <a href='javascript_required.html' onclick='try { show_blog(1502); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Retinoblastoma-like 2 (p130)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=RBL2' target='_blank'>HUGO:RBL2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=9894' target='_blank'>HGNC:9894</a> <a href='http://www.ncbi.nlm.nih.gov/gene/5934' target='_blank'>ENTREZ:5934</a> <a href='http://www.expasy.org/uniprot/Q08999' target='_blank'>UNIPROT:Q08999</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=RBL2' target='_blank'>GENECARDS:RBL2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=62850' target='_blank'>REACTOME:62850</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:5934' target='_blank'>KEGG:5934</a> <a href='http://atlasgeneticsoncology.org//Genes/RBL2ID443.html' target='_blank'>ATLASONC:RBL2ID443</a> <a href='http://wikipedia.org/wiki/RBL2' target='_blank'>WIKI:RBL2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>More important in quiescent cells. <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15838516' target='_blank'>PMID:15838516</a>. <BR>22 phophorylation sites in total. <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11157749' target='_blank'>PMID:11157749</a>. <BR>9 phosphorylation sites are CDK-dependants: 8 sites for CYCLIND-CDK4/6 (T401, S413, S639, S662, S672, S1035, S1044, S1080) and 1 site for CYCLINE-CDK2 (S1112). <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Shuttling of p130 between the nucleus and cytoplasm<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11756542' target='_blank'>PMID:11756542</a></p><hr><BR><b>Modification:</b><br>p130*|pho<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re290(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\"]); } catch (e) {}; return false;' title=\"c_s3 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR>c_re197(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\"]); } catch (e) {}; return false;' title=\"c_s3 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Degradation via the ubiquitin-proteasome system.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10773440' target='_blank'>PMID:10773440</a><BR>Degradation via SCF(SKP2) (=SKP1-Culin1-SKP2)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12717421' target='_blank'>PMID:12717421</a><BR>c_re1274(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\"]); } catch (e) {}; return false;' title=\"c_s3 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>p130 binds to and inhibits CYCLINA-CDK2, independantly of its phosphorylation state.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR>c_re1276(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\"]); } catch (e) {}; return false;' title=\"c_s3 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>p130 binds to and inhibits CYCLINE-CDK2, independantly of its phosphorylation state.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p></span>",
"s1485": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\">p130*</a> <a href='javascript_required.html' onclick='try { show_blog(1502); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Retinoblastoma-like 2 (p130)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=RBL2' target='_blank'>HUGO:RBL2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=9894' target='_blank'>HGNC:9894</a> <a href='http://www.ncbi.nlm.nih.gov/gene/5934' target='_blank'>ENTREZ:5934</a> <a href='http://www.expasy.org/uniprot/Q08999' target='_blank'>UNIPROT:Q08999</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=RBL2' target='_blank'>GENECARDS:RBL2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=62850' target='_blank'>REACTOME:62850</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:5934' target='_blank'>KEGG:5934</a> <a href='http://atlasgeneticsoncology.org//Genes/RBL2ID443.html' target='_blank'>ATLASONC:RBL2ID443</a> <a href='http://wikipedia.org/wiki/RBL2' target='_blank'>WIKI:RBL2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>More important in quiescent cells. <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15838516' target='_blank'>PMID:15838516</a>. <BR>22 phophorylation sites in total. <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11157749' target='_blank'>PMID:11157749</a>. <BR>9 phosphorylation sites are CDK-dependants: 8 sites for CYCLIND-CDK4/6 (T401, S413, S639, S662, S672, S1035, S1044, S1080) and 1 site for CYCLINE-CDK2 (S1112). <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Shuttling of p130 between the nucleus and cytoplasm<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11756542' target='_blank'>PMID:11756542</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a>|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re1276(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>p130 binds to and inhibits CYCLINE-CDK2, independantly of its phosphorylation state.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p></span>,",
"s301": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\">p130*</a> <a href='javascript_required.html' onclick='try { show_blog(1502); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Retinoblastoma-like 2 (p130)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=RBL2' target='_blank'>HUGO:RBL2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=9894' target='_blank'>HGNC:9894</a> <a href='http://www.ncbi.nlm.nih.gov/gene/5934' target='_blank'>ENTREZ:5934</a> <a href='http://www.expasy.org/uniprot/Q08999' target='_blank'>UNIPROT:Q08999</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=RBL2' target='_blank'>GENECARDS:RBL2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=62850' target='_blank'>REACTOME:62850</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:5934' target='_blank'>KEGG:5934</a> <a href='http://atlasgeneticsoncology.org//Genes/RBL2ID443.html' target='_blank'>ATLASONC:RBL2ID443</a> <a href='http://wikipedia.org/wiki/RBL2' target='_blank'>WIKI:RBL2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>More important in quiescent cells. <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15838516' target='_blank'>PMID:15838516</a>. <BR>22 phophorylation sites in total. <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11157749' target='_blank'>PMID:11157749</a>. <BR>9 phosphorylation sites are CDK-dependants: 8 sites for CYCLIND-CDK4/6 (T401, S413, S639, S662, S672, S1035, S1044, S1080) and 1 site for CYCLINE-CDK2 (S1112). <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Shuttling of p130 between the nucleus and cytoplasm<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11756542' target='_blank'>PMID:11756542</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s305\", \"s308\"]) } catch (e) {}; return false;' title=\"s305 s308 2 modifs\">DP2*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s303\", \"s310\"]) } catch (e) {}; return false;' title=\"s303 s310 2 modifs\">E2F4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s304\", \"s309\"]) } catch (e) {}; return false;' title=\"s304 s309 2 modifs\">HDAC1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s621\", \"s622\"]) } catch (e) {}; return false;' title=\"s621 s622 2 modifs\">SIN3B</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s306\", \"s307\"]) } catch (e) {}; return false;' title=\"s306 s307 2 modifs\">SUV39H1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP2*:E2F4:HDAC1:SIN3B:SUV39H1:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re288(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>HDAC1 and Sin3B associate to the promoteurs via E2F4 and p130/p107<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11959842' target='_blank'>PMID:11959842</a><BR>HDAC1 and SUV39H1 associate to the promoteurs via E2F4 and p130/p107<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s691\"]); } catch (e) {}; return false;' title=\"c_s691 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/3_4.gif'/> REF=3 <span style='color:orange'>FUNC=4</span></p></span>,",
"s312": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]) } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\">p130*</a> <a href='javascript_required.html' onclick='try { show_blog(1502); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Retinoblastoma-like 2 (p130)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=RBL2' target='_blank'>HUGO:RBL2</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=9894' target='_blank'>HGNC:9894</a> <a href='http://www.ncbi.nlm.nih.gov/gene/5934' target='_blank'>ENTREZ:5934</a> <a href='http://www.expasy.org/uniprot/Q08999' target='_blank'>UNIPROT:Q08999</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=RBL2' target='_blank'>GENECARDS:RBL2</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=62850' target='_blank'>REACTOME:62850</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:5934' target='_blank'>KEGG:5934</a> <a href='http://atlasgeneticsoncology.org//Genes/RBL2ID443.html' target='_blank'>ATLASONC:RBL2ID443</a> <a href='http://wikipedia.org/wiki/RBL2' target='_blank'>WIKI:RBL2</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s3\", \"c_s1501\", \"c_s691\", \"c_s690\"]); } catch (e) {}; return false;' title=\"c_s3 c_s1501 c_s691 c_s690 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>More important in quiescent cells. <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15838516' target='_blank'>PMID:15838516</a>. <BR>22 phophorylation sites in total. <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11157749' target='_blank'>PMID:11157749</a>. <BR>9 phosphorylation sites are CDK-dependants: 8 sites for CYCLIND-CDK4/6 (T401, S413, S639, S662, S672, S1035, S1044, S1080) and 1 site for CYCLINE-CDK2 (S1112). <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Shuttling of p130 between the nucleus and cytoplasm<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11756542' target='_blank'>PMID:11756542</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s305\", \"s308\"]) } catch (e) {}; return false;' title=\"s305 s308 2 modifs\">DP2*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s303\", \"s310\"]) } catch (e) {}; return false;' title=\"s303 s310 2 modifs\">E2F4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s304\", \"s309\"]) } catch (e) {}; return false;' title=\"s304 s309 2 modifs\">HDAC1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s621\", \"s622\"]) } catch (e) {}; return false;' title=\"s621 s622 2 modifs\">SIN3B</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s306\", \"s307\"]) } catch (e) {}; return false;' title=\"s306 s307 2 modifs\">SUV39H1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a>|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP2*:E2F4:HDAC1:SIN3B:SUV39H1:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re290(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s690\"]); } catch (e) {}; return false;' title=\"c_s690 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15769944' target='_blank'>PMID:15769944</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_4.gif'/> REF=2 <span style='color:orange'>FUNC=4</span></p></span>,",
"c_s1471": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]) } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\">p21CIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(4003); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase inhibitor 1A (p21, Cip1)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDKN1A' target='_blank'>HUGO:CDKN1A</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1784' target='_blank'>HGNC:1784</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1026' target='_blank'>ENTREZ:1026</a> <a href='http://www.expasy.org/uniprot/P38936' target='_blank'>UNIPROT:P38936</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDKN1A' target='_blank'>GENECARDS:CDKN1A</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87048' target='_blank'>REACTOME:87048</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1026' target='_blank'>KEGG:1026</a> <a href='http://atlasgeneticsoncology.org//Genes/CDKN1AID139.html' target='_blank'>ATLASONC:CDKN1AID139</a> <a href='http://wikipedia.org/wiki/CDKN1A' target='_blank'>WIKI:CDKN1A</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;MAPK&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/MAPK/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>Induced by p53.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10498883' target='_blank'>PMID:10498883</a><BR>Degraded by the ubiquitin-proteasome system.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9736735' target='_blank'>PMID:9736735</a></p><hr><BR><b>Modification:</b><br>p21CIP1*<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re178(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1471\"]); } catch (e) {}; return false;' title=\"c_s1471 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>All three Cip/Kip family members direct the accumulation of cylinD-CDK complexes in the nucleus. <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR>c_re262(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1471\"]); } catch (e) {}; return false;' title=\"c_s1471 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Inhibition of PCNA by p21.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a><BR>c_re324:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1471\"]); } catch (e) {}; return false;' title=\"c_s1471 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16775416' target='_blank'>PMID:16775416</a><BR>c_re325:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1471\"]); } catch (e) {}; return false;' title=\"c_s1471 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR>c_re604(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1471\"]); } catch (e) {}; return false;' title=\"c_s1471 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation at T145 is catalyzed by the protein serine/threonine kinase Akt<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16775416' target='_blank'>PMID:16775416</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15798220' target='_blank'>PMID:15798220</a><BR>Phosphorylation of p21 at Thr-145 by AKT-1 induce its cytoplasmic localization.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11231573' target='_blank'>PMID:11231573</a><BR></p></span>",
"s1512": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]) } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\">p21CIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(4003); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase inhibitor 1A (p21, Cip1)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDKN1A' target='_blank'>HUGO:CDKN1A</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1784' target='_blank'>HGNC:1784</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1026' target='_blank'>ENTREZ:1026</a> <a href='http://www.expasy.org/uniprot/P38936' target='_blank'>UNIPROT:P38936</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDKN1A' target='_blank'>GENECARDS:CDKN1A</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87048' target='_blank'>REACTOME:87048</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1026' target='_blank'>KEGG:1026</a> <a href='http://atlasgeneticsoncology.org//Genes/CDKN1AID139.html' target='_blank'>ATLASONC:CDKN1AID139</a> <a href='http://wikipedia.org/wiki/CDKN1A' target='_blank'>WIKI:CDKN1A</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;MAPK&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/MAPK/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>Induced by p53.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10498883' target='_blank'>PMID:10498883</a><BR>Degraded by the ubiquitin-proteasome system.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9736735' target='_blank'>PMID:9736735</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"s1512\", \"s779\", \"s775\"]) } catch (e) {}; return false;' title=\"c_s1471 s1512 s779 s775 4 modifs\">p21CIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p21CIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s787\"]); } catch (e) {}; return false;' title=\"c_s787 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s787\"]); } catch (e) {}; return false;' title=\"c_s787 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re327:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s787\"]); } catch (e) {}; return false;' title=\"c_s787 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p></span>,",
"s779": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]) } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\">p21CIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(4003); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase inhibitor 1A (p21, Cip1)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDKN1A' target='_blank'>HUGO:CDKN1A</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1784' target='_blank'>HGNC:1784</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1026' target='_blank'>ENTREZ:1026</a> <a href='http://www.expasy.org/uniprot/P38936' target='_blank'>UNIPROT:P38936</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDKN1A' target='_blank'>GENECARDS:CDKN1A</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87048' target='_blank'>REACTOME:87048</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1026' target='_blank'>KEGG:1026</a> <a href='http://atlasgeneticsoncology.org//Genes/CDKN1AID139.html' target='_blank'>ATLASONC:CDKN1AID139</a> <a href='http://wikipedia.org/wiki/CDKN1A' target='_blank'>WIKI:CDKN1A</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;MAPK&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/MAPK/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>Induced by p53.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10498883' target='_blank'>PMID:10498883</a><BR>Degraded by the ubiquitin-proteasome system.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9736735' target='_blank'>PMID:9736735</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s780\", \"s253\"]) } catch (e) {}; return false;' title=\"s780 s253 2 modifs\">CDK4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"s1512\", \"s779\", \"s775\"]) } catch (e) {}; return false;' title=\"c_s1471 s1512 s779 s775 4 modifs\">p21CIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK4:CyclinD*:p21CIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re325:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>,",
"s775": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]) } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\">p21CIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(4003); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase inhibitor 1A (p21, Cip1)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDKN1A' target='_blank'>HUGO:CDKN1A</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1784' target='_blank'>HGNC:1784</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1026' target='_blank'>ENTREZ:1026</a> <a href='http://www.expasy.org/uniprot/P38936' target='_blank'>UNIPROT:P38936</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDKN1A' target='_blank'>GENECARDS:CDKN1A</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=87048' target='_blank'>REACTOME:87048</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1026' target='_blank'>KEGG:1026</a> <a href='http://atlasgeneticsoncology.org//Genes/CDKN1AID139.html' target='_blank'>ATLASONC:CDKN1AID139</a> <a href='http://wikipedia.org/wiki/CDKN1A' target='_blank'>WIKI:CDKN1A</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;MAPK&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/MAPK/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s1471\", \"c_s787\", \"c_s781\", \"c_s776\"]); } catch (e) {}; return false;' title=\"c_s1471 c_s787 c_s781 c_s776 4 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>Induced by p53.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10498883' target='_blank'>PMID:10498883</a><BR>Degraded by the ubiquitin-proteasome system.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9736735' target='_blank'>PMID:9736735</a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s774\", \"s250\"]) } catch (e) {}; return false;' title=\"s774 s250 2 modifs\">CDK6</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"s1512\", \"s779\", \"s775\"]) } catch (e) {}; return false;' title=\"c_s1471 s1512 s779 s775 4 modifs\">p21CIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK6:CyclinD*:p21CIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re324:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16775416' target='_blank'>PMID:16775416</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>,",
"c_s646": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\">p27KIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(4001); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase inhibitor 1B (p27, Kip1)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDKN1B' target='_blank'>HUGO:CDKN1B</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1785' target='_blank'>HGNC:1785</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1027' target='_blank'>ENTREZ:1027</a> <a href='http://www.expasy.org/uniprot/P46527' target='_blank'>UNIPROT:P46527</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDKN1B' target='_blank'>GENECARDS:CDKN1B</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=198633' target='_blank'>REACTOME:198633</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1027' target='_blank'>KEGG:1027</a> <a href='http://atlasgeneticsoncology.org//Genes/CDKN1BID116.html' target='_blank'>ATLASONC:CDKN1BID116</a> <a href='http://wikipedia.org/wiki/CDKN1B' target='_blank'>WIKI:CDKN1B</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br>p27KIP1*|Thr187_pho<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re169(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\"]); } catch (e) {}; return false;' title=\"c_s646 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of p27 by cyclin E/CDK2 at Thr-187 results in targeting p27 for its degradation by proteolysis<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR>c_re196(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\"]); } catch (e) {}; return false;' title=\"c_s646 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Proteolysis degradation via the SCF(SKP2) system.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12851486' target='_blank'>PMID:12851486</a><BR>Preliminary phosphorylation and cytoplasm export needed for degradation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11355576' target='_blank'>PMID:11355576</a><BR></p></span>",
"c_s645": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\">p27KIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(4001); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase inhibitor 1B (p27, Kip1)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDKN1B' target='_blank'>HUGO:CDKN1B</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1785' target='_blank'>HGNC:1785</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1027' target='_blank'>ENTREZ:1027</a> <a href='http://www.expasy.org/uniprot/P46527' target='_blank'>UNIPROT:P46527</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDKN1B' target='_blank'>GENECARDS:CDKN1B</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=198633' target='_blank'>REACTOME:198633</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1027' target='_blank'>KEGG:1027</a> <a href='http://atlasgeneticsoncology.org//Genes/CDKN1BID116.html' target='_blank'>ATLASONC:CDKN1BID116</a> <a href='http://wikipedia.org/wiki/CDKN1B' target='_blank'>WIKI:CDKN1B</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br>p27KIP1*<br>in nucleus<br><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re169(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s645\"]); } catch (e) {}; return false;' title=\"c_s645 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of p27 by cyclin E/CDK2 at Thr-187 results in targeting p27 for its degradation by proteolysis<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR>c_re170(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s645\"]); } catch (e) {}; return false;' title=\"c_s645 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Complex CYCLINE-CDK2 inhibited by its interaction with CKI.<BR>c_re171(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s645\"]); } catch (e) {}; return false;' title=\"c_s645 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Complex CYCLINA-CDK2 inhibited by its interaction with CKI<BR>c_re178(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s645\"]); } catch (e) {}; return false;' title=\"c_s645 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>All three Cip/Kip family members direct the accumulation of cylinD-CDK complexes in the nucleus. <BR>c_re180(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s645\"]); } catch (e) {}; return false;' title=\"c_s645 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>The complex CYCLIND-CDK stability increases when bound to a Cip/Kip family member.<BR>c_re269(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s645\"]); } catch (e) {}; return false;' title=\"c_s645 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of p27 at Thr-157 by AKT-1 induce its cytoplasmic localization.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12851486' target='_blank'>PMID:12851486</a><BR></p></span>",
"s649": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\">p27KIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(4001); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase inhibitor 1B (p27, Kip1)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDKN1B' target='_blank'>HUGO:CDKN1B</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1785' target='_blank'>HGNC:1785</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1027' target='_blank'>ENTREZ:1027</a> <a href='http://www.expasy.org/uniprot/P46527' target='_blank'>UNIPROT:P46527</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDKN1B' target='_blank'>GENECARDS:CDKN1B</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=198633' target='_blank'>REACTOME:198633</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1027' target='_blank'>KEGG:1027</a> <a href='http://atlasgeneticsoncology.org//Genes/CDKN1BID116.html' target='_blank'>ATLASONC:CDKN1BID116</a> <a href='http://wikipedia.org/wiki/CDKN1B' target='_blank'>WIKI:CDKN1B</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"s649\", \"s653\", \"s652\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 s649 s653 s652 5 modifs\">p27KIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p27KIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re170(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Complex CYCLINE-CDK2 inhibited by its interaction with CKI.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p></span>,",
"s653": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\">p27KIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(4001); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase inhibitor 1B (p27, Kip1)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDKN1B' target='_blank'>HUGO:CDKN1B</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1785' target='_blank'>HGNC:1785</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1027' target='_blank'>ENTREZ:1027</a> <a href='http://www.expasy.org/uniprot/P46527' target='_blank'>UNIPROT:P46527</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDKN1B' target='_blank'>GENECARDS:CDKN1B</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=198633' target='_blank'>REACTOME:198633</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1027' target='_blank'>KEGG:1027</a> <a href='http://atlasgeneticsoncology.org//Genes/CDKN1BID116.html' target='_blank'>ATLASONC:CDKN1BID116</a> <a href='http://wikipedia.org/wiki/CDKN1B' target='_blank'>WIKI:CDKN1B</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s780\", \"s253\"]) } catch (e) {}; return false;' title=\"s780 s253 2 modifs\">CDK4</a>|Thr172_pho:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"s649\", \"s653\", \"s652\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 s649 s653 s652 5 modifs\">p27KIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK4:CyclinD*:p27KIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re175(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>,",
"s652": "<span class='bubble'><b><big>Protein<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\">p27KIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(4001); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><p class=\"bubble-cyan\"><b>Identifiers</b><BR>Cyclin-dependent kinase inhibitor 1B (p27, Kip1)<BR><a href='http://www.genenames.org/cgi-bin/quick_search.pl?.cgifields=type&amp;type=equals&amp;num=50&amp;submit=Submit&amp;search=CDKN1B' target='_blank'>HUGO:CDKN1B</a> <a href='http://www.genenames.org/data/hgnc_data.php?hgnc_id=1785' target='_blank'>HGNC:1785</a> <a href='http://www.ncbi.nlm.nih.gov/gene/1027' target='_blank'>ENTREZ:1027</a> <a href='http://www.expasy.org/uniprot/P46527' target='_blank'>UNIPROT:P46527</a> <a href='http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=CDKN1B' target='_blank'>GENECARDS:CDKN1B</a> <a href='http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&amp;ID=198633' target='_blank'>REACTOME:198633</a> <a href='http://www.genome.jp/dbget-bin/www_bget?hsa:1027' target='_blank'>KEGG:1027</a> <a href='http://atlasgeneticsoncology.org//Genes/CDKN1BID116.html' target='_blank'>ATLASONC:CDKN1BID116</a> <a href='http://wikipedia.org/wiki/CDKN1B' target='_blank'>WIKI:CDKN1B</a></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;EMT&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;EMT_REGULATORS&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../emtcellmotility/EMT_REGULATORS/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Apoptosis&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;APOPTOSIS_GENES&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../apoptosis/APOPTOSIS_GENES/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINA&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINA/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Survival&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/master/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;PI3K_AKT_MTOR&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../survival/PI3K_AKT_MTOR/index.html\", [\"c_s646\", \"c_s645\", \"c_s742\", \"c_s725\", \"c_s724\"]); } catch (e) {}; return false;' title=\"c_s646 c_s645 c_s742 c_s725 c_s724 5 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a></p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s774\", \"s250\"]) } catch (e) {}; return false;' title=\"s774 s250 2 modifs\">CDK6</a>|Thr_pho:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"s649\", \"s653\", \"s652\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 s649 s653 s652 5 modifs\">p27KIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK6:CyclinD*:p27KIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re174(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_4.gif'/> REF=5 <span style='color:orange'>FUNC=4</span></p></span>,",
"c_s1500": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1500\"]) } catch (e) {}; return false;' title=\"c_s1500 1 modifs\">BAF250*:&#8203;DP1*:&#8203;E2F1:&#8203;RB1</a> <a href='javascript_required.html' onclick='try { show_blog(2619); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s335\", \"s99\"]) } catch (e) {}; return false;' title=\"c_s335 s99 2 modifs\">BAF250*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s98\", \"s117\"]) } catch (e) {}; return false;' title=\"s98 s117 2 modifs\">DP1*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s97\", \"s116\"]) } catch (e) {}; return false;' title=\"s97 s116 2 modifs\">E2F1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s96\", \"s115\"]) } catch (e) {}; return false;' title=\"s96 s115 2 modifs\">RB1</a>|pho|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:BAF250*:DP1*:E2F1:RB1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1500\"]); } catch (e) {}; return false;' title=\"c_s1500 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_4.gif'/> REF=5 <span style='color:orange'>FUNC=4</span></p></span>",
"c_s741": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s741\", \"c_s721\", \"c_s722\", \"c_s723\"]) } catch (e) {}; return false;' title=\"c_s741 c_s721 c_s722 c_s723 4 modifs\">CDK2:&#8203;CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(2822); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Tyr14_pho|Tyr15_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s741\"]); } catch (e) {}; return false;' title=\"c_s741 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s741\"]); } catch (e) {}; return false;' title=\"c_s741 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p></span>",
"c_s721": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s741\", \"c_s721\", \"c_s722\", \"c_s723\"]) } catch (e) {}; return false;' title=\"c_s741 c_s721 c_s722 c_s723 4 modifs\">CDK2:&#8203;CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(2822); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re306:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7799941' target='_blank'>PMID:7799941</a><BR>c_re147(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7629134' target='_blank'>PMID:7629134</a><BR>c_re170(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s721\"]); } catch (e) {}; return false;' title=\"c_s721 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Complex CYCLINE-CDK2 inhibited by its interaction with CKI.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p></span>",
"c_s722": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s741\", \"c_s721\", \"c_s722\", \"c_s723\"]) } catch (e) {}; return false;' title=\"c_s741 c_s721 c_s722 c_s723 4 modifs\">CDK2:&#8203;CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(2822); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>|Thr380_pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s722\"]); } catch (e) {}; return false;' title=\"c_s722 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s722\"]); } catch (e) {}; return false;' title=\"c_s722 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re248(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s722\"]); } catch (e) {}; return false;' title=\"c_s722 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Cyclin E phosphorylation by CDK2 at Thr-380.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR>Autophosphorylation of the complex CYCLINE/CDK2 at Thr-380 and Thr-62. Phosphorylation at Thr-380 also by GSK-3B. Two other sites of regulation: Ser-372 et Ser-384<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16131838' target='_blank'>PMID:16131838</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/1_5.gif'/> REF=1 <span style='color:red'>FUNC=5</span></p></span>",
"c_s723": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s741\", \"c_s721\", \"c_s722\", \"c_s723\"]) } catch (e) {}; return false;' title=\"c_s741 c_s721 c_s722 c_s723 4 modifs\">CDK2:&#8203;CyclinE*</a> <a href='javascript_required.html' onclick='try { show_blog(2822); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re147(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7629134' target='_blank'>PMID:7629134</a><BR>c_re169(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of p27 by cyclin E/CDK2 at Thr-187 results in targeting p27 for its degradation by proteolysis<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR>c_re248(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Cyclin E phosphorylation by CDK2 at Thr-380.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR>Autophosphorylation of the complex CYCLINE/CDK2 at Thr-380 and Thr-62. Phosphorylation at Thr-380 also by GSK-3B. Two other sites of regulation: Ser-372 et Ser-384<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16131838' target='_blank'>PMID:16131838</a><BR>c_re289:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR>c_re327:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR>c_re1275:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR>c_re1276(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s723\"]); } catch (e) {}; return false;' title=\"c_s723 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>p130 binds to and inhibits CYCLINE-CDK2, independantly of its phosphorylation state.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>",
"c_s1502": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1502\"]) } catch (e) {}; return false;' title=\"c_s1502 1 modifs\">CDK2:&#8203;CyclinE*:&#8203;p107*</a> <a href='javascript_required.html' onclick='try { show_blog(4102); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s23\", \"s1490\"]) } catch (e) {}; return false;' title=\"c_s23 s1490 2 modifs\">p107*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p107*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re1275:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1502\"]); } catch (e) {}; return false;' title=\"c_s1502 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p></span>",
"c_s1501": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1501\"]) } catch (e) {}; return false;' title=\"c_s1501 1 modifs\">CDK2:&#8203;CyclinE*:&#8203;p130*</a> <a href='javascript_required.html' onclick='try { show_blog(1846); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s3\", \"s1485\", \"s301\", \"s312\"]) } catch (e) {}; return false;' title=\"c_s3 s1485 s301 s312 4 modifs\">p130*</a>|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p130*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re1276(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s1501\"]); } catch (e) {}; return false;' title=\"c_s1501 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>p130 binds to and inhibits CYCLINE-CDK2, independantly of its phosphorylation state.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p></span>",
"c_s787": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s787\"]) } catch (e) {}; return false;' title=\"c_s787 1 modifs\">CDK2:&#8203;CyclinE*:&#8203;p21CIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(2879); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>|Thr160_pho:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"s1512\", \"s779\", \"s775\"]) } catch (e) {}; return false;' title=\"c_s1471 s1512 s779 s775 4 modifs\">p21CIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p21CIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s787\"]); } catch (e) {}; return false;' title=\"c_s787 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s787\"]); } catch (e) {}; return false;' title=\"c_s787 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re327:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s787\"]); } catch (e) {}; return false;' title=\"c_s787 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p></span>",
"c_s742": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s742\"]) } catch (e) {}; return false;' title=\"c_s742 1 modifs\">CDK2:&#8203;CyclinE*:&#8203;p27KIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(90); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\", \"c_s31\", \"s1489\", \"s1484\", \"s786\", \"s237\", \"s216\", \"s215\", \"s218\", \"s212\"]) } catch (e) {}; return false;' title=\"c_s528 c_s31 s1489 s1484 s786 s237 s216 s215 s218 s212 10 modifs\">CDK2</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s529\", \"c_s29\", \"s1488\", \"s1483\", \"s785\", \"s238\", \"s217\", \"s214\", \"s219\", \"s213\"]) } catch (e) {}; return false;' title=\"c_s529 c_s29 s1488 s1483 s785 s238 s217 s214 s219 s213 10 modifs\">CyclinE*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"s649\", \"s653\", \"s652\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 s649 s653 s652 5 modifs\">p27KIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK2:CyclinE*:p27KIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re170(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s742\"]); } catch (e) {}; return false;' title=\"c_s742 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Complex CYCLINE-CDK2 inhibited by its interaction with CKI.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p></span>",
"c_s781": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s781\"]) } catch (e) {}; return false;' title=\"c_s781 1 modifs\">CDK4:&#8203;CyclinD*:&#8203;p21CIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(959); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s780\", \"s253\"]) } catch (e) {}; return false;' title=\"s780 s253 2 modifs\">CDK4</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"s1512\", \"s779\", \"s775\"]) } catch (e) {}; return false;' title=\"c_s1471 s1512 s779 s775 4 modifs\">p21CIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK4:CyclinD*:p21CIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re325:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s781\"]); } catch (e) {}; return false;' title=\"c_s781 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>",
"c_s725": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s725\"]) } catch (e) {}; return false;' title=\"c_s725 1 modifs\">CDK4:&#8203;CyclinD*:&#8203;p27KIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(957); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s780\", \"s253\"]) } catch (e) {}; return false;' title=\"s780 s253 2 modifs\">CDK4</a>|Thr172_pho:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"s649\", \"s653\", \"s652\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 s649 s653 s652 5 modifs\">p27KIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK4:CyclinD*:p27KIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re175(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s725\"]); } catch (e) {}; return false;' title=\"c_s725 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>",
"c_s776": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s776\"]) } catch (e) {}; return false;' title=\"c_s776 1 modifs\">CDK6:&#8203;CyclinD*:&#8203;p21CIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(2710); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s774\", \"s250\"]) } catch (e) {}; return false;' title=\"s774 s250 2 modifs\">CDK6</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\", \"s1512\", \"s779\", \"s775\"]) } catch (e) {}; return false;' title=\"c_s1471 s1512 s779 s775 4 modifs\">p21CIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK6:CyclinD*:p21CIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re324:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16775416' target='_blank'>PMID:16775416</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s776\"]); } catch (e) {}; return false;' title=\"c_s776 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_5.gif'/> REF=5 <span style='color:red'>FUNC=5</span></p></span>",
"c_s724": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s724\"]) } catch (e) {}; return false;' title=\"c_s724 1 modifs\">CDK6:&#8203;CyclinD*:&#8203;p27KIP1*</a> <a href='javascript_required.html' onclick='try { show_blog(2707); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s774\", \"s250\"]) } catch (e) {}; return false;' title=\"s774 s250 2 modifs\">CDK6</a>|Thr_pho:<a href='javascript_required.html' onclick='try { show_markers([\"s778\", \"s773\", \"s252\", \"s249\"]) } catch (e) {}; return false;' title=\"s778 s773 s252 s249 4 modifs\">CyclinD*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"c_s646\", \"c_s645\", \"s649\", \"s653\", \"s652\"]) } catch (e) {}; return false;' title=\"c_s646 c_s645 s649 s653 s652 5 modifs\">p27KIP1*</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK6:CyclinD*:p27KIP1*<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re174(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re92:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>c_re298(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s724\"]); } catch (e) {}; return false;' title=\"c_s724 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>Phosphorylation of pRB<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a><BR>dissociation of HDAC1 (during the G1 to S transition)<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10778858' target='_blank'>PMID:10778858</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11520855' target='_blank'>PMID:11520855</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7736585' target='_blank'>PMID:7736585</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9425340' target='_blank'>PMID:9425340</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9190208' target='_blank'>PMID:9190208</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/5_4.gif'/> REF=5 <span style='color:orange'>FUNC=4</span></p></span>",
"c_s749": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s749\"]) } catch (e) {}; return false;' title=\"c_s749 1 modifs\">CDK7:&#8203;CyclinH*:&#8203;MNAT1</a> <a href='javascript_required.html' onclick='try { show_blog(620); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s209\"]) } catch (e) {}; return false;' title=\"s209 1 modifs\">CDK7</a>|Thr170_pho:<a href='javascript_required.html' onclick='try { show_markers([\"s210\"]) } catch (e) {}; return false;' title=\"s210 1 modifs\">CyclinH*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s211\"]) } catch (e) {}; return false;' title=\"s211 1 modifs\">MNAT1</a><br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:CDK7:CyclinH*:MNAT1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINH&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINH/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re245(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK7 activation by its phosphorylation at Thr-170<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11355576' target='_blank'>PMID:11355576</a><BR>c_re147(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7629134' target='_blank'>PMID:7629134</a><BR>c_re174(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re175(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16782892' target='_blank'>PMID:16782892</a><BR>c_re216(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7799941' target='_blank'>PMID:7799941</a><BR>c_re310(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s749\"]); } catch (e) {}; return false;' title=\"c_s749 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>CDK activity activated by its phosphorylation by CAK-complex<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11959850' target='_blank'>PMID:11959850</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/4_5.gif'/> REF=4 <span style='color:red'>FUNC=5</span></p></span>",
"c_s717": "<span class='bubble'><b><big>Complex<br><a href='javascript_required.html' onclick='try { show_markers([\"c_s717\"]) } catch (e) {}; return false;' title=\"c_s717 1 modifs\">DP1*:&#8203;E2F1:&#8203;RB1</a> <a href='javascript_required.html' onclick='try { show_blog(1091); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a></big></b><BR><p><hr><BR><b>Modification:</b><br><a href='javascript_required.html' onclick='try { show_markers([\"s98\", \"s117\"]) } catch (e) {}; return false;' title=\"s98 s117 2 modifs\">DP1*</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s97\", \"s116\"]) } catch (e) {}; return false;' title=\"s97 s116 2 modifs\">E2F1</a>:<a href='javascript_required.html' onclick='try { show_markers([\"s96\", \"s115\"]) } catch (e) {}; return false;' title=\"s96 s115 2 modifs\">RB1</a>|pho|pho|pho<br>in nucleus<br><p class=\"bubble-cyan\"><b>Identifiers</b><BR>NAME:DP1*:E2F1:RB1<BR></p><p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F1&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F1/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>c_re323(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>):<BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR>c_re291:(&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_s717\"]); } catch (e) {}; return false;' title=\"c_s717 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>) <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8380224' target='_blank'>PMID:8380224</a>; <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>; <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10773440' target='_blank'>PMID:10773440</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/3_5.gif'/> REF=3 <span style='color:red'>FUNC=5</span></p></span>",
"c_s691": "<span class='bubble'></span>",
"c_s690": "<span class='bubble'></span>",
"c_re147": "<span class='bubble'>Reaction state_transition c_re147 <a href='javascript_required.html' onclick='try { show_blog(9746); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s721\"]) } catch (e) {}; return false;' title=\"c_s721 1 modifs\">CDK2:&#8203;CyclinE*@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s723\"]) } catch (e) {}; return false;' title=\"c_s723 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*@nucleus</a><BR><br><b>Reaction regulators:</b><BR><dl><dt>Catalysis</dt><dd><ol><li><a href='javascript_required.html' onclick='try { show_markers([\"c_s749\"]) } catch (e) {}; return false;' title=\"c_s749 1 modifs\">CDK7|&#8203;Thr170_pho:&#8203;CyclinH*:&#8203;MNAT1@nucleus</a></ol></dd></dl><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re147\"]); } catch (e) {}; return false;' title=\"c_re147 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re147\"]); } catch (e) {}; return false;' title=\"c_re147 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re147\"]); } catch (e) {}; return false;' title=\"c_re147 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINH&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINH/index.html\", [\"c_re147\"]); } catch (e) {}; return false;' title=\"c_re147 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>CDK activity stimulated by its CAK-complex phosphorylation.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12459251' target='_blank'>PMID:12459251</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12814430' target='_blank'>PMID:12814430</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7629134' target='_blank'>PMID:7629134</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/1_4.gif'/> REF=1 <span style='color:orange'>FUNC=4</span></p>          <BR>        \n</span>",
"c_re169": "<span class='bubble'>Reaction state_transition c_re169 <a href='javascript_required.html' onclick='try { show_blog(9770); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s645\"]) } catch (e) {}; return false;' title=\"c_s645 1 modifs\">p27KIP1*@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s646\"]) } catch (e) {}; return false;' title=\"c_s646 1 modifs\">p27KIP1*|&#8203;Thr187_pho@nucleus</a><BR><br><b>Reaction regulators:</b><BR><dl><dt>Catalysis</dt><dd><ol><li><a href='javascript_required.html' onclick='try { show_markers([\"c_s723\"]) } catch (e) {}; return false;' title=\"c_s723 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*@nucleus</a></ol></dd></dl><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re169\"]); } catch (e) {}; return false;' title=\"c_re169 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re169\"]); } catch (e) {}; return false;' title=\"c_re169 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re169\"]); } catch (e) {}; return false;' title=\"c_re169 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_re169\"]); } catch (e) {}; return false;' title=\"c_re169 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>Phosphorylation of p27 by cyclin E/CDK2 at Thr-187 results in targeting p27 for its degradation by proteolysis<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p>          <BR>        \n</span>",
"c_re170": "<span class='bubble'>Reaction heterodimer_association c_re170 <a href='javascript_required.html' onclick='try { show_blog(9772); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s721\"]) } catch (e) {}; return false;' title=\"c_s721 1 modifs\">CDK2:&#8203;CyclinE*@nucleus</a> + <a href='javascript_required.html' onclick='try { show_markers([\"c_s645\"]) } catch (e) {}; return false;' title=\"c_s645 1 modifs\">p27KIP1*@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s742\"]) } catch (e) {}; return false;' title=\"c_s742 1 modifs\">CDK2:&#8203;CyclinE*:&#8203;p27KIP1*@nucleus</a><BR><br><b>No reaction regulators</b><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re170\"]); } catch (e) {}; return false;' title=\"c_re170 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re170\"]); } catch (e) {}; return false;' title=\"c_re170 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re170\"]); } catch (e) {}; return false;' title=\"c_re170 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINH&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINH/index.html\", [\"c_re170\"]); } catch (e) {}; return false;' title=\"c_re170 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>Complex CYCLINE-CDK2 inhibited by its interaction with CKI.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=10385618' target='_blank'>PMID:10385618</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p>          <BR>        \n</span>",
"c_re248": "<span class='bubble'>Reaction state_transition c_re248 <a href='javascript_required.html' onclick='try { show_blog(9876); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s723\"]) } catch (e) {}; return false;' title=\"c_s723 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s722\"]) } catch (e) {}; return false;' title=\"c_s722 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*|&#8203;Thr380_pho@nucleus</a><BR><br><b>Reaction regulators:</b><BR><dl><dt>Catalysis</dt><dd><ol><li><a href='javascript_required.html' onclick='try { show_markers([\"c_s419\"]) } catch (e) {}; return false;' title=\"c_s419 1 modifs\">GSK3_beta_*@nucleus</a></ol></dd></dl><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re248\"]); } catch (e) {}; return false;' title=\"c_re248 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLIND&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLIND/index.html\", [\"c_re248\"]); } catch (e) {}; return false;' title=\"c_re248 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re248\"]); } catch (e) {}; return false;' title=\"c_re248 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re248\"]); } catch (e) {}; return false;' title=\"c_re248 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>Cyclin E phosphorylation by CDK2 at Thr-380.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR>Autophosphorylation of the complex CYCLINE/CDK2 at Thr-380 and Thr-62. Phosphorylation at Thr-380 also by GSK-3B. Two other sites of regulation: Ser-372 et Ser-384<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=16131838' target='_blank'>PMID:16131838</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/1_4.gif'/> REF=1 <span style='color:orange'>FUNC=4</span></p>          <BR>        \n</span>",
"c_re250": "<span class='bubble'>Reaction dissociation c_re250 <a href='javascript_required.html' onclick='try { show_blog(9878); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s722\"]) } catch (e) {}; return false;' title=\"c_s722 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*|&#8203;Thr380_pho@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s529\"]) } catch (e) {}; return false;' title=\"c_s529 1 modifs\">CyclinE*|&#8203;Thr380_pho@nucleus</a> + <a href='javascript_required.html' onclick='try { show_markers([\"c_s528\"]) } catch (e) {}; return false;' title=\"c_s528 1 modifs\">CDK2|&#8203;Thr160_pho@nucleus</a><BR><br><b>No reaction regulators</b><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re250\"]); } catch (e) {}; return false;' title=\"c_re250 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re250\"]); } catch (e) {}; return false;' title=\"c_re250 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/1_5.gif'/> REF=1 <span style='color:red'>FUNC=5</span></p>          <BR>        \n</span>",
"c_re251": "<span class='bubble'>Reaction state_transition c_re251 <a href='javascript_required.html' onclick='try { show_blog(9880); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s528\"]) } catch (e) {}; return false;' title=\"c_s528 1 modifs\">CDK2|&#8203;Thr160_pho@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s31\"]) } catch (e) {}; return false;' title=\"c_s31 1 modifs\">CDK2@nucleus</a><BR><br><b>Reaction regulators:</b><BR><dl><dt>Catalysis</dt><dd><ol><li><a href='javascript_required.html' onclick='try { show_markers([\"c_s663\"]) } catch (e) {}; return false;' title=\"c_s663 1 modifs\">CDKN3@nucleus</a></ol></dd></dl><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re251\"]); } catch (e) {}; return false;' title=\"c_re251 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re251\"]); } catch (e) {}; return false;' title=\"c_re251 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11355576' target='_blank'>PMID:11355576</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p>          <BR>        \n</span>",
"c_re252": "<span class='bubble'>Reaction state_transition c_re252 <a href='javascript_required.html' onclick='try { show_blog(9882); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s529\"]) } catch (e) {}; return false;' title=\"c_s529 1 modifs\">CyclinE*|&#8203;Thr380_pho@nucleus</a> &rarr; degraded<BR><br><b>No reaction regulators</b><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re252\"]); } catch (e) {}; return false;' title=\"c_re252 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re252\"]); } catch (e) {}; return false;' title=\"c_re252 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>Degradation via the ubiquitin/proteasome system.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=8861947' target='_blank'>PMID:8861947</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/1_4.gif'/> REF=1 <span style='color:orange'>FUNC=4</span></p>          <BR>        \n</span>",
"c_re289": "<span class='bubble'>Reaction state_transition c_re289 <a href='javascript_required.html' onclick='try { show_blog(9934); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s691\"]) } catch (e) {}; return false;' title=\"c_s691 1 modifs\">DP2*:&#8203;E2F4:&#8203;HDAC1:&#8203;SIN3B:&#8203;SUV39H1:&#8203;p130*@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s690\"]) } catch (e) {}; return false;' title=\"c_s690 1 modifs\">DP2*:&#8203;E2F4:&#8203;HDAC1:&#8203;SIN3B:&#8203;SUV39H1:&#8203;p130*|&#8203;pho@nucleus</a><BR><br><b>Reaction regulators:</b><BR><dl><dt>Catalysis</dt><dd><ol><li><a href='javascript_required.html' onclick='try { show_markers([\"c_s723\"]) } catch (e) {}; return false;' title=\"c_s723 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*@nucleus</a><li><a href='javascript_required.html' onclick='try { show_markers([\"c_s724\"]) } catch (e) {}; return false;' title=\"c_s724 1 modifs\">CDK6|&#8203;Thr_pho:&#8203;CyclinD*:&#8203;p27KIP1*@nucleus</a><li><a href='javascript_required.html' onclick='try { show_markers([\"c_s725\"]) } catch (e) {}; return false;' title=\"c_s725 1 modifs\">CDK4|&#8203;Thr172_pho:&#8203;CyclinD*:&#8203;p27KIP1*@nucleus</a><li><a href='javascript_required.html' onclick='try { show_markers([\"c_s776\"]) } catch (e) {}; return false;' title=\"c_s776 1 modifs\">CDK6:&#8203;CyclinD*:&#8203;p21CIP1*@nucleus</a><li><a href='javascript_required.html' onclick='try { show_markers([\"c_s781\"]) } catch (e) {}; return false;' title=\"c_s781 1 modifs\">CDK4:&#8203;CyclinD*:&#8203;p21CIP1*@nucleus</a></ol></dd></dl><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re289\"]); } catch (e) {}; return false;' title=\"c_re289 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re289\"]); } catch (e) {}; return false;' title=\"c_re289 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re289\"]); } catch (e) {}; return false;' title=\"c_re289 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_re289\"]); } catch (e) {}; return false;' title=\"c_re289 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re289\"]); } catch (e) {}; return false;' title=\"c_re289 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P27KIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P27KIP/index.html\", [\"c_re289\"]); } catch (e) {}; return false;' title=\"c_re289 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re289\"]); } catch (e) {}; return false;' title=\"c_re289 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_re289\"]); } catch (e) {}; return false;' title=\"c_re289 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/1_4.gif'/> REF=1 <span style='color:orange'>FUNC=4</span></p>          <BR>        \n</span>",
"c_re306": "<span class='bubble'>Reaction heterodimer_association c_re306 <a href='javascript_required.html' onclick='try { show_blog(9946); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s29\"]) } catch (e) {}; return false;' title=\"c_s29 1 modifs\">CyclinE*@nucleus</a> + <a href='javascript_required.html' onclick='try { show_markers([\"c_s31\"]) } catch (e) {}; return false;' title=\"c_s31 1 modifs\">CDK2@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s721\"]) } catch (e) {}; return false;' title=\"c_s721 1 modifs\">CDK2:&#8203;CyclinE*@nucleus</a><BR><br><b>No reaction regulators</b><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re306\"]); } catch (e) {}; return false;' title=\"c_re306 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re306\"]); } catch (e) {}; return false;' title=\"c_re306 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=7799941' target='_blank'>PMID:7799941</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/1_5.gif'/> REF=1 <span style='color:red'>FUNC=5</span></p>          <BR>        \n</span>",
"c_re323": "<span class='bubble'>Reaction unknown_transition c_re323 <a href='javascript_required.html' onclick='try { show_blog(9960); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s1500\"]) } catch (e) {}; return false;' title=\"c_s1500 1 modifs\">BAF250*:&#8203;DP1*:&#8203;E2F1:&#8203;RB1|&#8203;pho|&#8203;pho@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s717\"]) } catch (e) {}; return false;' title=\"c_s717 1 modifs\">DP1*:&#8203;E2F1:&#8203;RB1|&#8203;pho|&#8203;pho|&#8203;pho@nucleus</a> + <a href='javascript_required.html' onclick='try { show_markers([\"c_s335\"]) } catch (e) {}; return false;' title=\"c_s335 1 modifs\">BAF250*|&#8203;pho@nucleus</a><BR><br><b>Reaction regulators:</b><BR><dl><dt>Catalysis</dt><dd><ol><li><a href='javascript_required.html' onclick='try { show_markers([\"c_s723\"]) } catch (e) {}; return false;' title=\"c_s723 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*@nucleus</a></ol></dd></dl><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re323\"]); } catch (e) {}; return false;' title=\"c_re323 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re323\"]); } catch (e) {}; return false;' title=\"c_re323 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re323\"]); } catch (e) {}; return false;' title=\"c_re323 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;RB&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/RB/index.html\", [\"c_re323\"]); } catch (e) {}; return false;' title=\"c_re323 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>pRB phosphorylation<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=9315635' target='_blank'>PMID:9315635</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR>Brg1 phosphorylation <BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11420722' target='_blank'>PMID:11420722</a><BR>Brg1 (in the SWI/SNF complex) and pRB are phosphorylated, simultaneously with the complex dissociation. Phosphorylation of pRB<BR>Phosphorylation of Brg1 (SWI/SNF complex)<BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_4.gif'/> REF=2 <span style='color:orange'>FUNC=4</span></p>          <BR>        \n</span>",
"c_re327": "<span class='bubble'>Reaction heterodimer_association c_re327 <a href='javascript_required.html' onclick='try { show_blog(9968); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s723\"]) } catch (e) {}; return false;' title=\"c_s723 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*@nucleus</a> + <a href='javascript_required.html' onclick='try { show_markers([\"c_s1471\"]) } catch (e) {}; return false;' title=\"c_s1471 1 modifs\">p21CIP1*@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s787\"]) } catch (e) {}; return false;' title=\"c_s787 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*:&#8203;p21CIP1*@nucleus</a><BR><br><b>No reaction regulators</b><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re327\"]); } catch (e) {}; return false;' title=\"c_re327 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re327\"]); } catch (e) {}; return false;' title=\"c_re327 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re327\"]); } catch (e) {}; return false;' title=\"c_re327 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;P21CIP&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/P21CIP/index.html\", [\"c_re327\"]); } catch (e) {}; return false;' title=\"c_re327 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12836612' target='_blank'>PMID:12836612</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_5.gif'/> REF=0 <span style='color:red'>FUNC=5</span></p>          <BR>        \n</span>",
"c_re329": "<span class='bubble'>Reaction state_transition c_re329 <a href='javascript_required.html' onclick='try { show_blog(9972); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s721\"]) } catch (e) {}; return false;' title=\"c_s721 1 modifs\">CDK2:&#8203;CyclinE*@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s741\"]) } catch (e) {}; return false;' title=\"c_s741 1 modifs\">CDK2|&#8203;Tyr14_pho|&#8203;Tyr15_pho:&#8203;CyclinE*@nucleus</a><BR><br><b>Reaction regulators:</b><BR><dl><dt>Catalysis</dt><dd><ol><li><a href='javascript_required.html' onclick='try { show_markers([\"c_s411\"]) } catch (e) {}; return false;' title=\"c_s411 1 modifs\">WEE1@nucleus</a></ol></dd></dl><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re329\"]); } catch (e) {}; return false;' title=\"c_re329 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re329\"]); } catch (e) {}; return false;' title=\"c_re329 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re329\"]); } catch (e) {}; return false;' title=\"c_re329 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;WEE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/WEE/index.html\", [\"c_re329\"]); } catch (e) {}; return false;' title=\"c_re329 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/0_4.gif'/> REF=0 <span style='color:orange'>FUNC=4</span></p>          <BR>        \n</span>",
"c_re1275": "<span class='bubble'>Reaction heterodimer_association c_re1275 <a href='javascript_required.html' onclick='try { show_blog(10710); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s723\"]) } catch (e) {}; return false;' title=\"c_s723 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*@nucleus</a> + <a href='javascript_required.html' onclick='try { show_markers([\"c_s23\"]) } catch (e) {}; return false;' title=\"c_s23 1 modifs\">p107*@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s1502\"]) } catch (e) {}; return false;' title=\"c_s1502 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*:&#8203;p107*@nucleus</a><BR><br><b>No reaction regulators</b><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re1275\"]); } catch (e) {}; return false;' title=\"c_re1275 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;CYCLINE&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/CYCLINE/index.html\", [\"c_re1275\"]); } catch (e) {}; return false;' title=\"c_re1275 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re1275\"]); } catch (e) {}; return false;' title=\"c_re1275 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_re1275\"]); } catch (e) {}; return false;' title=\"c_re1275 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a>, <a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p>          <BR>        \n</span>",
"c_re1276": "<span class='bubble'>Reaction heterodimer_association c_re1276 <a href='javascript_required.html' onclick='try { show_blog(10712); } catch (e) {}; return false;' title=\"go to blog\"><img border='0' width='16' height='16' src=\"../../../map_icons/misc/blog.png\" alt='blog'></a><BR><br><a href='javascript_required.html' onclick='try { show_markers([\"c_s3\"]) } catch (e) {}; return false;' title=\"c_s3 1 modifs\">p130*|&#8203;pho@nucleus</a> + <a href='javascript_required.html' onclick='try { show_markers([\"c_s723\"]) } catch (e) {}; return false;' title=\"c_s723 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*@nucleus</a> &rarr; <a href='javascript_required.html' onclick='try { show_markers([\"c_s1501\"]) } catch (e) {}; return false;' title=\"c_s1501 1 modifs\">CDK2|&#8203;Thr160_pho:&#8203;CyclinE*:&#8203;p130*|&#8203;pho@nucleus</a><BR><br><b>No reaction regulators</b><BR>          <BR>            <p class=\"bubble-LightGreen\"><b>Maps_Modules</b><BR>&nbsp;Cell cycle&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/master/index.html\", [\"c_re1276\"]); } catch (e) {}; return false;' title=\"c_re1276 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a>&nbsp;/&nbsp;E2F4&nbsp;<a href='javascript_required.html' onclick='try { nv_perform(\"nv_open_module\", window, \"../../cellcycle/E2F4/index.html\", [\"c_re1276\"]); } catch (e) {}; return false;' title=\"c_re1276 1 modifs\"><img border='0' src=\"../../../map_icons/map.png\" alt='map' /></a><BR></p><p class=\"bubble-LightGoldenRodYellow\"><b>References</b><BR>p130 binds to and inhibits CYCLINE-CDK2, independantly of its phosphorylation state.<BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=15456871' target='_blank'>PMID:15456871</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=12006580' target='_blank'>PMID:12006580</a><BR><a href='http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;amp;Cmd=ShowDetailView&amp;amp;TermToSearch=11237530' target='_blank'>PMID:11237530</a><BR></p><p class=\"bubble-Khaki\"><b>Confidence</b><BR><img width='100' height='22' border='0' src='../../../map_icons/confidence/2_5.gif'/> REF=2 <span style='color:red'>FUNC=5</span></p>          <BR>        \n</span>"}