XRCC1

Protein XRCC1 map

Identifiers
XRCC1 , X-ray repair complementing defective repair in Chinese hamster cells 1
HUGO:XRCC1 HGNC:12828 ENTREZ:7515 UNIPROT:P18887 GENECARDS:XRCC1 REACTOME:67456 KEGG:7515 ATLASONC:GC_XRCC1 WIKI:XRCC1

Maps_Modules
 DNA repair  map  / BER  map
 DNA repair  map  / A_NHEJ  map
 DNA repair  map  / NER  map

References
PMID:20211143, PMID:8978692, PMID:8264637, PMID:15703371, PMID:19847258, PMID:16697054, PMID:14726013, PMID:20227374
For A_NHEJ (alt_NHEJ or B_NHEJ or MMEJ):
PMID:21376743, PMID:24050180, PMID:22743550

XRCC1|​pho@default

References
d_re70:( DNA repair  map ) PMID:18971944
d_re22( DNA repair  map ):
PMID:18398454
PMID:16449207
RECQL5 activates BER via XRCC1 and PARP1
PMID:22973052

XRCC1@default

References
d_re70:( DNA repair  map ) PMID:18971944


Modifications:
In compartment: default
  1. XRCC1@default map

  2. XRCC1|​pho@default map

Participates in complexes:
In compartment: Nucleus

  1. LIG3:​PARP1|​PolyADPribose_unk|​pho:​XRCC1|​pho@Nucleus map

In compartment: default

  1. LIG3:​XRCC1|​pho@default map

  2. PARP2|​unk|​pho:​PNK*:​POLB:​WRN|​ace:​XRCC1|​pho@default map
  3. PARP1|​PolyADPribose_unk|​pho:​PNK*:​POLB:​WRN|​ace:​XRCC1|​pho@default map
  4. CHTF18:​PCNA:​POLD*:​POLE*:​POLK:​RFC*:​RPA1:​RPA2|​pho:​RPA3:​XRCC1|​pho@default map

Participates in reactions:
As Reactant or Product:

  1. XRCC1|​pho@default map + LIG3@default map + PARP1|​PolyADPribose_unk|​pho@Nucleus map map LIG3:​PARP1|​PolyADPribose_unk|​pho:​XRCC1|​pho@Nucleus map

  2. POLB@default map + XRCC1|​pho@default map + PARP1|​PolyADPribose_unk|​pho@Nucleus map + WRN|​ace@default map + PNK*@default map map PARP1|​PolyADPribose_unk|​pho:​PNK*:​POLB:​WRN|​ace:​XRCC1|​pho@default map
  3. POLE*@default map + POLD*@default map + RFC*@Nucleus map + PCNA@default map + CHTF18@default map + POLK@default map + XRCC1|​pho@default map + RPA1:​RPA2|​pho:​RPA3@default map map CHTF18:​PCNA:​POLD*:​POLE*:​POLK:​RFC*:​RPA1:​RPA2|​pho:​RPA3:​XRCC1|​pho@default map
  4. LIG3@default map + XRCC1|​pho@default map map LIG3:​XRCC1|​pho@default map
  5. PARP2|​unk|​pho@default map + WRN|​ace@default map + PNK*@default map + XRCC1|​pho@default map + POLB@default map map PARP2|​unk|​pho:​PNK*:​POLB:​WRN|​ace:​XRCC1|​pho@default map
  6. XRCC1@default map map XRCC1|​pho@default map

As Catalyser:

  1. gA_NHEJ_DNA_st5*@Nucleus map map gA_NHEJ_DNA_st6*@Nucleus map

  2. gTC-NER_GG-NER_DNA_st5*@Nucleus map map gTC-NER_GG-NER_DNA_st6*@Nucleus map
  3. gShP_BER_M-glyc_st5_B-glyc_DNA_st5*@Nucleus map map gShP_BER_M-glyc_st5_B-glyc_DNA_st6*@Nucleus map
  4. gTC-NER_GG-NER_DNA_st4*@Nucleus map + dNTPs@Nucleus map map gTC-NER_GG-NER_DNA_st5*@Nucleus map
  5. gShP_BER_M-glyc_st4_B-glyc_DNA_st4*@Nucleus map + dNTPs@Nucleus map map gShP_BER_M-glyc_st5_B-glyc_DNA_st5*@Nucleus map

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