XAF1

Protein XAF1 map

Identifiers
XIAP associated factor 1
HUGO:XAF1 HGNC:30932 ENTREZ:54739 UNIPROT:Q6GPH4 GENECARDS:XAF1 REACTOME:357255 KEGG:54739 ATLASONC:XAF1ID44095ch17p13 WIKI:XAF1

Maps_Modules
 Apoptosis  map  / APOPTOSIS_GENES  map

XAF1@Nucleus

References
a_re666( Apoptosis  map ):
PMID:11175744
in vitro, Y2H
in vitro, GST pulldown
in transfected Hela cells, coIP
in Hela cells expressing fluorescent proein fusions, XAF1 is nuclear and its co-expression with XIAP induces XIAP nuclear retention
in vitro, XIAP mediated inhibition of CASP3 activity is blocked by XAF1
in HEL-299 human embryonic lung cells, XAF1 expression reverts the protective effect of XIAP expression toward serum deprivation-induced cell death


Modifications:
In compartment: Nucleus
  1. XAF1@Nucleus map

Participates in complexes:
In compartment: Nucleus

  1. XAF1:​XIAP|​S87_unk@Nucleus map

Participates in reactions:
As Reactant or Product:

  1. XIAP|​S87_unk@Cytoplasm map + XAF1@Nucleus map map XAF1:​XIAP|​S87_unk@Nucleus map

As Catalyser:

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