VEGFR2*

Gene VEGFR2* map

Identifiers
kinase insert domain receptor (a type III receptor tyrosine kinase)
HUGO:KDR HGNC:6307 ENTREZ:3791 UNIPROT:P35968 GENECARDS:KDR REACTOME:67174 KEGG:3791 ATLASONC:GC_KDR WIKI:KDR

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / ECM  map

References
PMID:21081489
MiR-200b Regulates Ets-1-associated Genes
Suppression of endogenous miR-200b induced MMP-1 and VEGFR2 expressions
Overexpression of Ets-1 did not completely reverse miR- 200b-associated MMP-1 and VEGFR2 down-regulation.
It indicates that miR-200b, apart from targeting Ets-1, might silence other target proteins involved in transcription of the indicated genes.
PMID:11166270
VEGFR2 is highly specific towards VEGFA.
PMID:11741095
PMID:13678960
However VEGFR2 also binds to processed forms of VEGF-C, D, E.
VEGFR2 is expressed in both vascular endothelial and lymphatic endothelial cells.
Its expression has also been demonstrated in several other cell types such as megakaryocytes and haematopoietic stemm cells.

gVEGFR2*@Nucleus

References
e_re373( EMT  map ):
PMID:21081489
MiR-200b Regulates Ets-1-associated Genes
Suppression of endogenous miR-200b induced MMP-1 and VEGFR2 expressions
Overexpression of Ets-1 did not completely reverse miR- 200b-associated MMP-1 and VEGFR2 down-regulation.
It indicates that miR-200b, apart from targeting Ets-1, might silence other target proteins involved in transcription of the indicated genes.


Modifications:
In compartment: Nucleus
  1. gVEGFR2*@Nucleus map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. gVEGFR2*@Nucleus map map rVEGFR2*@Nucleus map

    As Catalyser:

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