UBE2T

Protein UBE2T map

Identifiers
ubiquitin-conjugating enzyme E2T (putative)
HUGO:UBE2T HGNC:25009 ENTREZ:29089 UNIPROT:Q9NPD8 GENECARDS:UBE2T REACTOME:253538 KEGG:29089 ATLASONC:GC_UBE2T WIKI:UBE2T

Maps_Modules
 DNA repair  map  / FANCONI  map
 DNA repair  map  / NER  map

References
PMID:19686080, PMID:19622404, PMID:18931676
Link between Fanconi and NER
PMID:22615860

UBE2T|​k91_ubi@default

References
d_re213( DNA repair  map ):
PMID:19264559
FANCL induces UBE2T auto-ubiquitination on Lys91 by this inactivating UBE2T. This is a negative loop:
PMID:16916645

UBE2T@default

References
d_re14( DNA repair  map ):
Link between Fanconi and NER
PMID:22615860
d_re158( DNA repair  map ):
S phase checkpoint controls and induces FANCD2 monoubiquitusation to start Fanconi and HR
PMID:12239151
d_re213( DNA repair  map ):
PMID:19264559
FANCL induces UBE2T auto-ubiquitination on Lys91 by this inactivating UBE2T. This is a negative loop:
PMID:16916645
d_re252( DNA repair  map ):
Requirement for functional DNA polymerase eta in genome-wide repair by NER of UV-induced DNA damage during S phase:
PMID:20457011


Modifications:
In compartment: default
  1. UBE2T@default map

  2. UBE2T|​k91_ubi@default map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. UBE2T@default map map UBE2T|​k91_ubi@default map

    2. UBE2T|​k91_ubi@default map map degraded

    As Catalyser:

    1. gTC-NER_DNA_st2*@Nucleus map map gTC-NER_GG-NER_DNA_st3*@Nucleus map

    2. FANCD2|​pho@default map map FANCD2|​K561_ubi|​pho@default map
    3. FANCI|​pho@default map map FANCI|​K523_ubi|​pho@default map
    4. UBE2T@default map map UBE2T|​k91_ubi@default map
    5. gGG-NER_DNA_st1*@Nucleus map map gGG-NER_DNA_st2*@Nucleus map

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