TOP3A

Protein TOP3A map

Identifiers
topoisomerase (DNA) III alpha
HUGO:TOP3A HGNC:11992 ENTREZ:7156 UNIPROT:Q13472 GENECARDS:TOP3A REACTOME:66277 KEGG:7156 ATLASONC:GC_TOP3A WIKI:TOP3A

Maps_Modules
 DNA repair  map  / HR  map
 DNA repair  map  / FANCONI  map

References
For HR pathway
PMID:19772495, PMID:16697054, PMID:19847258
For Fanconi anemia pathway
PMID:19686080, PMID:19622404, PMID:18931676


Modifications:
In compartment: default
  1. TOP3A@default map

Participates in complexes:
In compartment: default

  1. BLM:​RMI1:​TOP3A@default map

  2. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​RPA1:​RPA2:​RPA3:​TOP3A@default map

Participates in reactions:
As Reactant or Product:

  1. TOP3A@default map + BLM@Nucleus map + RMI1@default map map BLM:​RMI1:​TOP3A@default map

  2. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map + TOP3A@default map + RPA1:​RPA2:​RPA3@default map map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​RPA1:​RPA2:​RPA3:​TOP3A@default map

As Catalyser:

  1. gHR_DNA_st1*@Nucleus map map gHR_DNA_st2*@Nucleus map

  2. gHR_DNA_st5*@Nucleus map map gHR_DNA_st6*@Nucleus map

Leave a Reply