TNFRSF1B

Protein TNFRSF1B map

Identifiers
tumor necrosis factor receptor superfamily member 1B
TNFR2
HUGO:TNFRSF1B HGNC:11917 ENTREZ:7133 UNIPROT:P20333 GENECARDS:TNFRSF1B KEGG:7133 ATLASONC:GC_TNFRSF1B WIKI:TNFRSF1B

Maps_Modules
 Survival  map  / MAPK  map

References
Upon ligand-induced TNFR1 trimerisation (not modelled) the TNFR1 death domain binds the death domain of the platform adapter protein TRADD. In contrast TNFR2 does not possess a death domain and instead binds directly to TRAF proteins (TRAF2).
PMID:11274345

TNFRSF1B@Plasma Membrane

References
s_mpk1_re124( Survival  map ):
Upon ligand-induced TNFR1 trimerisation (not modelled) the TNFR1 death domain binds the death domain of the platform adapter protein TRADD. In contrast TNFR2 does not possess a death domain and instead binds directly to TRAF proteins (TRAF2).
PMID:11274345


Modifications:
In compartment: Plasma Membrane
  1. TNFRSF1B@Plasma Membrane map

Participates in complexes:
In compartment: Cytoplasm

  1. TAK1*|​pho:​TNFRSF1B@Cytoplasm map

  2. MAP3K1|​pho:​TNFRSF1B@Cytoplasm map
  3. MAP3K5|​pho:​TNFRSF1B@Cytoplasm map
  4. MAP3K2_3*|​pho:​TNFRSF1B@Cytoplasm map

In compartment: Plasma Membrane

  1. TNFRSF1B:​TRAF2@Plasma Membrane map

Participates in reactions:
As Reactant or Product:

  1. TRAF2@Cytoplasm map + TNFRSF1B@Plasma Membrane map map TNFRSF1B:​TRAF2@Plasma Membrane map

  2. TNFRSF1B:​TRAF2@Plasma Membrane map + TAK1*@Cytoplasm map map TAK1*|​pho:​TNFRSF1B@Cytoplasm map
  3. MAP3K1@Cytoplasm map + TNFRSF1B:​TRAF2@Plasma Membrane map map MAP3K1|​pho:​TNFRSF1B@Cytoplasm map
  4. MAP3K2_3*@Cytoplasm map + TNFRSF1B:​TRAF2@Plasma Membrane map map MAP3K2_3*|​pho:​TNFRSF1B@Cytoplasm map
  5. TNFRSF1B:​TRAF2@Plasma Membrane map map ROS@Cytoplasm map
  6. TNFRSF1B:​TRAF2@Plasma Membrane map + MAP3K5@Cytoplasm map map MAP3K5|​pho:​TNFRSF1B@Cytoplasm map

As Catalyser:

  1. MAP2K4@Cytoplasm map map MAP2K4|​pho|​pho@Cytoplasm map

  2. MAP2K3@Cytoplasm map map MAP2K3|​pho|​pho@Cytoplasm map
  3. MAP2K7@Cytoplasm map map MAP2K7|​pho|​pho@Cytoplasm map
  4. MAP2K6@Cytoplasm map map MAP2K6|​pho|​pho@Cytoplasm map
  5. MEK*@Cytoplasm map map MEK*|​pho|​pho@Cytoplasm map

Leave a Reply