TNFRSF1A:TRADD:TRAF2

Complex TNFRSF1A:TRADD:TRAF2 map


Complex composition:

  1. TRADD map
  2. TNFRSF1A map
  3. TRAF2 map




TNFRSF1A:​TRADD:​TRAF2@Plasma Membrane

Identifiers
NAME:TNFRSF1A:TRADD:TRAF2

References
s_mpk1_re122( Survival  map ):
TRAF proteins are recruited to the TRADD-TNFR1 complex. TRADD couples TNFR1 to TRAF2.
PMID:11274345
s_mpk1_re123( Survival  map ):
TNF treatment is thought to result in the formation of a TRADD-RIP-TRAF2 complex at the membrane.
s_mpk1_re146( Survival  map ):
TRAF2 activation triggers a ROS pulse that causes the dissociation of Trx from ASK1.
s_s_mpk1_re123( Survival  map ):
s_s_mpk1_re146( Survival  map ):

Confidence
REF=0 FUNC=5


Modifications:
Participates in complexes:
In compartment: Plasma Membrane
  1. TNFRSF1A:​TRADD:​TRAF2@Plasma Membrane map

Participates in reactions:
As Reactant or Product:

  1. TRAF2@Cytoplasm map + TNFRSF1A:​TRADD@Plasma Membrane map map TNFRSF1A:​TRADD:​TRAF2@Plasma Membrane map

  2. RIPK1@Cytoplasm map + TNFRSF1A:​TRADD:​TRAF2@Plasma Membrane map map RIPK1:​TNFRSF1A:​TRADD:​TRAF2@Plasma Membrane map
  3. TNFRSF1A:​TRADD:​TRAF2@Plasma Membrane map map ROS@Cytoplasm map

As Catalyser:

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