TNFRSF1A:TRADD

Complex TNFRSF1A:TRADD map


Complex composition:

  1. TRADD map
  2. TNFRSF1A map




TNFRSF1A:​TRADD@Plasma Membrane

Identifiers
NAME:TNFRSF1A:TRADD

References
s_mpk1_re121( Survival  map ):
Upon ligand-induced TNFR1 trimerisation (not modelled) the TNFR1 death domain binds the death domain of the platform adapter protein TRADD. In contrast TNFR2 does not possess a death domain and instead binds directly to TRAF proteins.
PMID:11274345
s_mpk1_re122( Survival  map ):
TRAF proteins are recruited to the TRADD-TNFR1 complex. TRADD couples TNFR1 to TRAF2.
s_s_mpk1_re122( Survival  map ):

Confidence
REF=0 FUNC=5


Modifications:
Participates in complexes:
In compartment: Plasma Membrane
  1. TNFRSF1A:​TRADD@Plasma Membrane map

Participates in reactions:
As Reactant or Product:

  1. TNFRSF1A@Plasma Membrane map + TRADD@Cytoplasm map map TNFRSF1A:​TRADD@Plasma Membrane map

  2. TRAF2@Cytoplasm map + TNFRSF1A:​TRADD@Plasma Membrane map map TNFRSF1A:​TRADD:​TRAF2@Plasma Membrane map

As Catalyser:

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