TNF

Protein TNF map

Identifiers
tumor necrosis factor
TNFA, “tumor necrosis factor (TNF superfamily, member 2)”
HUGO:TNF HGNC:11892 ENTREZ:7124 UNIPROT:P01375 GENECARDS:TNF REACTOME:66221 KEGG:7124 ATLASONC:TNFaID319 WIKI:TNF

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / ECM  map
 Apoptosis  map  / TNF_RESPONSE  map

References
PMID:19411070
TNFa dramatically enhanced the protein stabilization of Snail1 through NF-kB mediated CSN2 induction.

TNF@Extracellular space

References
e_re1218( EMT  map ):
PMID:19411070
Activation of NFKB pathway by TNFa
TNFa dramatically enhanced the protein stabilization of Snail1 through NF-kB mediated CSN2 induction.


Modifications:
In compartment: Extracellular space
  1. TNF@Extracellular space map

Participates in complexes:
In compartment: TNFRSF1 Receptor Complex

  1. TNFRSF1A|​hm3:​TNF|​hm3@TNFRSF1 Receptor Complex map

Participates in reactions:
As Reactant or Product:

  1. TNF@Extracellular space map + TNFRSF1A@Cytoplasm map map TNFRSF1A|​hm3:​TNF|​hm3@TNFRSF1 Receptor Complex map

  2. TNF@Extracellular space map map NF-_kappa_B_p65*@Cytoplasm map

As Catalyser:

  1. TRADD@Cytoplasm map map TRADD@TNFRSF1 Receptor Complex map

  2. TRAF2@Cytoplasm map map TRAF2@TNFRSF1 Receptor Complex map
  3. DAB2IP@Cytoplasm map map DAB2IP@TNFRSF1 Receptor Complex map

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