Protein TIP60* 
Identifiers
K(lysine) acetyltransferase 5
“HIV-1 Tat interactive protein, 60kDa”, HTATIP
HUGO:KAT5 HGNC:5275 ENTREZ:10524 UNIPROT:Q92993 GENECARDS:KAT5 KEGG:10524 ATLASONC:HTATIPID40893ch11q13 WIKI:KAT5
Maps_Modules
EMT / EMT_REGULATORS
Apoptosis / MITOCH_METABOLISM
DNA repair / HR
DNA repair / FANCONI
References
synonym:TIP60
PMID:12551922, PMID:11927554, PMID:21574959, PMID:18085520
TIP60*@default
References
d_re166( DNA repair ):
Fanconi recognition complex as FA core complex recruits NER, HR, TLS proteins that collectively repair the ICL. If Fanconi proteins participating in the recognition are dysactivated, there is no any other mechanism to recognize ILSs, therefore, even if NER, HR and TLS are correct, they will not perform the repair without core Fanconi proteins.
PMID:19686080
Modifications:
In compartment: Nucleus
- TIP60*@Nucleus
In compartment: default
- TIP60*@default
Participates in complexes:
In compartment: default
- BRCA1:BRCA2:FANCD2|pho:FANCI|pho:H2AFX|pho|ubi:NBS1*|S343_pho:PCNA:RAD51:TIP60*@default
- BRCA1:BRCA2:FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho:H2AFX|pho|ubi:NBS1*|S343_pho:PCNA:RAD51:TIP60*@default
Participates in reactions:
As Reactant or Product:
- FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho@default + BRCA1|S988_pho|S1387_pho|S1423_pho|S1497_pho|S1524_pho|active@default + BRCA2@default + NBS1*|S343_pho@default + RAD51@default + PCNA@default + H2AFX|pho|ubi@default + TIP60*@default → BRCA1:BRCA2:FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho:H2AFX|pho|ubi:NBS1*|S343_pho:PCNA:RAD51:TIP60*@default
- BRCA1:BRCA2:FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho:H2AFX|pho|ubi:NBS1*|S343_pho:PCNA:RAD51:TIP60*@default → BRCA1:BRCA2:FANCD2|pho:FANCI|pho:H2AFX|pho|ubi:NBS1*|S343_pho:PCNA:RAD51:TIP60*@default
As Catalyser: