TIP60*

Protein TIP60* map

Identifiers
K(lysine) acetyltransferase 5
“HIV-1 Tat interactive protein, 60kDa”, HTATIP
HUGO:KAT5 HGNC:5275 ENTREZ:10524 UNIPROT:Q92993 GENECARDS:KAT5 KEGG:10524 ATLASONC:HTATIPID40893ch11q13 WIKI:KAT5

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 Apoptosis  map  / MITOCH_METABOLISM  map
 DNA repair  map  / HR  map
 DNA repair  map  / FANCONI  map

References
synonym:TIP60
PMID:12551922, PMID:11927554, PMID:21574959, PMID:18085520

TIP60*@default

References
d_re166( DNA repair  map ):
Fanconi recognition complex as FA core complex recruits NER, HR, TLS proteins that collectively repair the ICL. If Fanconi proteins participating in the recognition are dysactivated, there is no any other mechanism to recognize ILSs, therefore, even if NER, HR and TLS are correct, they will not perform the repair without core Fanconi proteins.
PMID:19686080


Modifications:
In compartment: Nucleus
  1. TIP60*@Nucleus map

In compartment: default

  1. TIP60*@default map

Participates in complexes:
In compartment: default

  1. BRCA1:​BRCA2:​FANCD2|​pho:​FANCI|​pho:​H2AFX|​pho|​ubi:​NBS1*|​S343_pho:​PCNA:​RAD51:​TIP60*@default map

  2. BRCA1:​BRCA2:​FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​H2AFX|​pho|​ubi:​NBS1*|​S343_pho:​PCNA:​RAD51:​TIP60*@default map

Participates in reactions:
As Reactant or Product:

  1. FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho@default map + BRCA1|​S988_pho|​S1387_pho|​S1423_pho|​S1497_pho|​S1524_pho|​active@default map + BRCA2@default map + NBS1*|​S343_pho@default map + RAD51@default map + PCNA@default map + H2AFX|​pho|​ubi@default map + TIP60*@default map map BRCA1:​BRCA2:​FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​H2AFX|​pho|​ubi:​NBS1*|​S343_pho:​PCNA:​RAD51:​TIP60*@default map

  2. BRCA1:​BRCA2:​FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​H2AFX|​pho|​ubi:​NBS1*|​S343_pho:​PCNA:​RAD51:​TIP60*@default map map BRCA1:​BRCA2:​FANCD2|​pho:​FANCI|​pho:​H2AFX|​pho|​ubi:​NBS1*|​S343_pho:​PCNA:​RAD51:​TIP60*@default map

As Catalyser:

  1. ATM|​hm2@Site of DNA damage map map ATM|​S1981_pho|​K3016_ace@Site of DNA damage map

  2. gHR_DNA_st2*@Nucleus map map gHR_DNA_st3*@Nucleus map
  3. gFanconi_DNA_st4*@Nucleus map map gHR_DNA_st2*@Nucleus map

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