TIAM1

Protein TIAM1 map

Identifiers
T-cell lymphoma invasion and metastasis 1
HUGO:TIAM1 HGNC:11805 ENTREZ:7074 UNIPROT:Q13009 GENECARDS:TIAM1 REACTOME:195051 ATLASONC:TIAM1ID42557ch21q22 WIKI:TIAM1

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / CYTOSKELETON_POLARITY  map
 Survival  map  / HEDGEHOG  map

References
PMID:12829230

TIAM1@Cytoplasm

References
e_re835( EMT  map ):
Cross-talk between small GTPase signaling pathways.
PMID:12134164
PMID:7673236
HRAS activates TIAM1 which is a GEF for Rac1.
RalBP1 (which is an effector for RalA and RalB) inactivates Rac1


Modifications:
In compartment: Cytoplasm
  1. TIAM1@Cytoplasm map

Participates in complexes:
In compartment: Cytoplasm

  1. PI3,4,5-P3:​TIAM1@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. Rac1_GEFs*@Cytoplasm map map TIAM1@Cytoplasm map

  2. TIAM1@Cytoplasm map map TIAM1@Cytoplasm map
  3. PI3,4,5-P3@Cytoplasm map + TIAM1@Cytoplasm map map PI3,4,5-P3:​TIAM1@Cytoplasm map

As Catalyser:

  1. GDP:​RAC1@Cytoplasm map + GTP@Cytoplasm map map GTP:​RAC1@Cytoplasm map + GDP@Cytoplasm map

Leave a Reply