succinate

Simple molecule succinate map
succinate@Mitochondrial Matrix

Identifiers
CHEBI:30031 KEGGCOMPOUND:C00042 CAS:56-14-4

Maps_Modules
 Apoptosis  map  / APOPTOSIS_GENES  map
 Apoptosis  map  / CASPASES  map
 Apoptosis  map  / MITOCH_METABOLISM  map

References
charge:2-

succinate@Cytoplasm

References
a_re387( Apoptosis  map ):
PMID:12351678
identification of PHD2 as a HIF1A prolyl hydroxylase
PMID:15652751
inhibition of HIF1A prolyl hydroxylation by succinate and fumarate
PMID:15721254
in 293 cells, OS9 interacts with HIF1 and PHD and promotes HIF1A prolylhydroxylation and degradation

succinate@Nucleus

References
a_re397( Apoptosis  map ):
PMID:11641274
PMID:12080085
PMID:12042299
PMID:12215170


Modifications:
In compartment: Cytoplasm
  1. succinate@Cytoplasm map

In compartment: Mitochondrial Matrix

  1. succinate@Mitochondrial Matrix map

In compartment: Mitochondrial intermembrane space

  1. succinate@Mitochondrial intermembrane space map

In compartment: Nucleus

  1. succinate@Nucleus map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. succinate@Mitochondrial Matrix map map succinate@Mitochondrial intermembrane space map

    2. succinate@Mitochondrial intermembrane space map map succinate@Cytoplasm map
    3. succinate@Mitochondrial Matrix map + ubiquinone@Mitochondrial inner membrane map map fumarate@Mitochondrial Matrix map + ubiquinol@Mitochondrial inner membrane map
    4. succinyl-CoA@Mitochondrial Matrix map + GDP@Mitochondrial Matrix map map succinate@Mitochondrial Matrix map + coenzyme A@Mitochondrial Matrix map + GTP@Mitochondrial Matrix map

    As Catalyser:

    1. HIF1A@Cytoplasm map + O_sub_2_endsub_@Cytoplasm map + 2-oxoglutarate@Cytoplasm map map HIF1A|​P564_hyd@Cytoplasm map + succinate@Cytoplasm map + CO_sub_2_endsub_@Cytoplasm map

    2. a_s3082 + O_sub_2_endsub_@Nucleus map + 2-oxoglutarate@Nucleus map map a_s2130 + CO_sub_2_endsub_@Nucleus map + succinate@Nucleus map

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