SKP2

Protein SKP2 map

Identifiers
S-phase kinase-associated protein 2 (p45)
HUGO:SKP2 HGNC:10901 ENTREZ:6502 UNIPROT:Q13309 GENECARDS:SKP2 REACTOME:405589 KEGG:6502 ATLASONC:GC_SKP2 WIKI:SKP2
Q13309

Maps_Modules
 DNA repair  map  / G1_S_CHECKPOINT  map
 DNA repair  map  / S_PHASE_CHECKPOINT  map
 DNA repair  map  / G2_M_CHECKPOINT  map
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:15459660
PMID:15147722


Modifications:
In compartment: default
  1. SKP2@default map

Participates in complexes:
In compartment: Cytoplasm

  1. CKS1B:​SKP2@Cytoplasm map

In compartment: Nucleus

  1. CKS1B:​CUL1:​SKP1:​SKP2@Nucleus map

  2. CDC53*:​RBX1:​SKP1:​SKP2@Nucleus map

In compartment: default

  1. CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@default map

Participates in reactions:
As Reactant or Product:

  1. _beta_TRCP*@default map + SKP1@default map + CUL1@default map + RBX1@default map + SKP2@default map map CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@default map

  2. S phase@Nucleus map map CKS1B:​CUL1:​SKP1:​SKP2@Nucleus map

As Catalyser:

  1. FANCM|​pho@default map map degraded

  2. CyclinD*@default map map degraded
  3. CyclinE*@default map map degraded
  4. CDC25A@default map map degraded
  5. CDC25B@default map map degraded
  6. WEE1|​pho@default map map degraded
  7. EMI1*|​pho@default map map degraded
  8. p27KIP1*|​pho|​pho@Nucleus map map p27KIP1*|​pho|​pho|​emp|​ubi|​ubi|​ubi@Cytoplasm map
  9. FOXO1|​T24_pho|​S256_pho|​S319_pho@Cytoplasm map map FOXO1|​T24_pho|​S322_ubi|​S256_pho|​S319_pho@Cytoplasm map

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