SKP1

Protein SKP1 map

Identifiers
S-phase kinase-associated protein 1
HUGO:SKP1 HGNC:10899 ENTREZ:6500 UNIPROT:P63208 GENECARDS:SKP1 REACTOME:101666 KEGG:6500 ATLASONC:GC_SKP1 WIKI:SKP1
“S-phase kinase-associated protein 1A (p19A)”, SKP1A

Maps_Modules
 Apoptosis  map  / MOMP_REGULATION  map
 Apoptosis  map  / TNF_RESPONSE  map
 DNA repair  map  / G1_S_CHECKPOINT  map
 DNA repair  map  / S_PHASE_CHECKPOINT  map
 DNA repair  map  / G2_M_CHECKPOINT  map
 Survival  map  / HEDGEHOG  map
 Survival  map  / PI3K_AKT_MTOR  map
 Survival  map  / WNT_NON_CANONICAL  map

References
Regulates Fanconi pathway in cell cycle dependent manner
PMID:19686080, PMID:19622404, PMID:18931676
For checkpoint
PMID:15459660
PMID:15340381
PMID:12820959


Modifications:
In compartment: default
  1. SKP1@default map

Participates in complexes:
In compartment: Cytoplasm

  1. CUL1:​RBX1:​SKP1:​_beta_TRCP*@Cytoplasm map

In compartment: Nucleus

  1. CKS1B:​CUL1:​SKP1:​SKP2@Nucleus map

  2. CDC53*:​RBX1:​SKP1:​SKP2@Nucleus map
  3. CDC53*:​FBW7*:​RBX1:​SKP1@Nucleus map

In compartment: default

  1. CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@default map

Participates in reactions:
As Reactant or Product:

  1. _beta_TRCP*@default map + SKP1@default map + CUL1@default map + RBX1@default map + SKP2@default map map CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@default map

  2. S phase@Nucleus map map CKS1B:​CUL1:​SKP1:​SKP2@Nucleus map

As Catalyser:

  1. NFKBIA|​pho@Cytoplasm map map NFKBIA|​pho|​ubi@Cytoplasm map

  2. BimEL*|​S69_pho|​S98_pho|​S94_pho|​S93_pho@Cytoplasm map map degraded
  3. FANCM|​pho@default map map degraded
  4. CyclinD*@default map map degraded
  5. CyclinE*@default map map degraded
  6. CDC25A@default map map degraded
  7. CDC25B@default map map degraded
  8. WEE1|​pho@default map map degraded
  9. EMI1*|​pho@default map map degraded
  10. PHLPP*|​S869_pho|​S847_pho@Cytoplasm map map PHLPP*|​S869_pho|​S847_pho|​ubi|​ubi@Cytoplasm map
  11. PDCD4|​S67_pho@Cytoplasm map map PDCD4|​S67_pho|​ubi@Cytoplasm map
  12. p27KIP1*|​pho|​pho@Nucleus map map p27KIP1*|​pho|​pho|​emp|​ubi|​ubi|​ubi@Cytoplasm map
  13. GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho:​SUFU:​ULK3@Cytoplasm map map GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho|​ubi|​ubi|​ubi|​ubi:​SUFU:​ULK3@Cytoplasm map
  14. GLI2-185*|​S789_pho|​S805_pho|​S817_pho|​S847_pho|​S792_pho|​S808_pho|​S820_pho|​S850_pho|​S801_pho|​S813_pho|​S844_pho|​pho:​SUFU:​ULK3@Cytoplasm map map GLI2-185*|​S789_pho|​S805_pho|​S817_pho|​S847_pho|​S792_pho|​S808_pho|​S820_pho|​S850_pho|​S801_pho|​S813_pho|​S844_pho|​pho|​ubi|​ubi:​SUFU:​ULK3@Cytoplasm map
  15. GLI2-185*|​S792_pho|​S808_pho|​S820_pho|​S850_pho|​S801_pho|​S813_pho|​S844_pho|​pho|​S385_pho|​S1011_pho:​SUFU:​ULK3@Cytoplasm map map GLI2-185*|​S792_pho|​S808_pho|​S820_pho|​S850_pho|​S801_pho|​S813_pho|​S844_pho|​pho|​ubi|​ubi|​S385_pho|​S1011_pho:​SUFU:​ULK3@Cytoplasm map

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