s_s_wnc3_re31

Reaction state_transition s_s_wnc3_re31 map

CNA*:​CNB*:​ERK2*:​MEK1*:​NFAT*|​pho@Nucleus map + gAP-1_ARRE binding sites*@Nucleus map + JUN@Nucleus map + FOS@Nucleus map AP-1_ARRE binding sites*:​FOS:​JUN:​NFAT*@Nucleus map + CNA*:​CNB*@Nucleus map + ERK2*@Nucleus map + MEK1*@Nucleus map

Reaction regulators:

Catalysis
  1. CNA*:​CNB*:​ERK2*:​MEK1*:​NFAT*|​pho@Nucleus map



Maps_Modules
 Survival  map  / WNT_NON_CANONICAL  map

References
Phosphorylation of NFAT leads to increased DNA binding of NFAT -> increased gene transcription
PMID15657416
Not sure if dissociation of calcineurin and ERK/MEK occurs

Confidence
REF=0 FUNC=2


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