s_s_wnc2_re45

Reaction heterodimer_association s_s_wnc2_re45 map

(NFAT*:​PPP3CB_sub_trunc_endsub_*:​PPP3R*)|​active@Cytoplasm map + KPNB1@Cytoplasm map + Tubulin-_alpha_*@Cytoplasm map + TNPO1@Cytoplasm map KPNB1:​NFAT*:​PPP3CB_sub_trunc_endsub_*:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map

No reaction regulators

Maps_Modules
 Survival  map  / WNT_NON_CANONICAL  map

References
Tubulin-alpha binds both NFAT and KPNB1 after dephosphorylation of NFAT.
PMID:21278340
TNPO1 is a transport protein that helps in the import of proteins into the nucleus. Although it has been described with associated with NRON, it is most likely that it binds first to NFAT complex, making this complex ready for import, then NRON can bind to this complex to hinder the import of the complex
PMID:21709260

Confidence
REF=2 FUNC=2


Leave a Reply