s_s_mpk1_re32

Reaction state_transition s_s_mpk1_re32 map

Caspase9*@Cytoplasm map Caspase9*|​pho@Cytoplasm map

Reaction regulators:

Catalysis
  1. ERK*|​pho|​pho@Cytoplasm map



References
Caspase9 is phosphorylated on Thr125 in a MEK1/2-dependent manner in vivo. Furthermore caspase9 is efficiently phosphorylated on Thr125 by ERK in vitro suggesting that it is targeted directly by ERK in vivo. This is one of the ways ERK plays its anti-apoptotic role.
PMID:12792650

Confidence
REF=1 FUNC=4


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