s_s_mpk1_re270

Reaction dissociation s_s_mpk1_re270 map

s_s_mpk1_s953 → BCL2@Mitochondria map + BAD@Mitochondria map

Reaction regulators:

Inhibition
  1. AKT*|​pho@Cytoplasm map



References
Akt phosphorylation of the apoptosis-inducing protein BAD creates a binding site for 14-3-3 proteins and prevents BAD from binding to Bcl-2 family members Bcl-2 and Bcl-XL thus releasing them for a cell survival response.
PMID:12040186

Confidence
REF=0 FUNC=4


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