s_s_mpk1_re214

Reaction state_transition s_s_mpk1_re214 map

BAD@Mitochondria map Apoptosis@Cytoplasm map

No reaction regulators

References
A mitochondrial pool of Raf-1 (C-RAF) molecules which do not activate MEK reportedly exert their prosurvival effects upstream of cytochrome c release by phosphorylating the pro-apoptotic Bcl-2 family member BAD. Phosphorylation of BAD results in its translocation to the cytosol and ultimately in the inhibition of cytochrome c release.
PMID:12107820

Confidence
REF=0 FUNC=0


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