s_s_mpk1_re179

Reaction state_transition s_s_mpk1_re179 map

p53*@Nucleus map p53*|​pho@Nucleus map

Reaction regulators:

Catalysis
  1. p38*|​pho|​pho@Nucleus map
  2. ATM@Cytoplasm map



References
P53 is a nuclear P38 target.
Activated P38 phosphorylates P53 at several residues including Ser33 and thereby increases the transcriptional activity of P53.
ATM phosphorylates P53 at ser15 and stabilize it.
PMID:20506250 PMID:21614932 PMID:15140942

Confidence
REF=2 FUNC=4


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