s_s_mpk1_re143

Reaction heterodimer_association s_s_mpk1_re143 map

GADD45*@Cytoplasm map + MAP3K4@Cytoplasm map GADD45*:​MAP3K4|​pho@Cytoplasm map

No reaction regulators

References
Expression of GADD45 genes in mammalian cells strongly activates co-expressed MTK1 as well as P38 and JNK the MAPKs downstream of MTK1.
GADD45alpha/beta are direct MEKK4 interactors. They are involved in genotoxin regulation of MEKK4 signalling to JNK and P38
PMID:21614932 PMID:11274345

Confidence
REF=0 FUNC=5


Leave a Reply