s_s_mpk1_re121

Reaction heterodimer_association s_s_mpk1_re121 map

TNFRSF1A@Plasma Membrane map + TRADD@Cytoplasm map TNFRSF1A:​TRADD@Plasma Membrane map

No reaction regulators

References
Upon ligand-induced TNFR1 trimerisation (not modelled) the TNFR1 death domain binds the death domain of the platform adapter protein TRADD. In contrast TNFR2 does not possess a death domain and instead binds directly to TRAF proteins.
PMID:11274345

Confidence
REF=0 FUNC=5


Leave a Reply