RPTOR

Protein RPTOR map

Identifiers
regulatory associated protein of MTOR, complex 1
HUGO:RPTOR HGNC:30287 ENTREZ:57521 UNIPROT:Q8N122 GENECARDS:RPTOR REACTOME:153287 KEGG:57521 ATLASONC:GC_RPTOR WIKI:RPTOR

Maps_Modules
 Apoptosis  map  / AKT_MTOR  map
 Apoptosis  map  / APOPTOSIS_GENES  map
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:19864431
PMID:12150925
PMID:15755954

RPTOR|​S722_pho|​S792_pho@Cytoplasm

References
a_re370( Apoptosis  map ):
PMID:18439900
in HEK293
a_re372( Apoptosis  map ):
logical:re372_s2093=FALSE

RPTOR@Cytoplasm

References
a_re370( Apoptosis  map ):
PMID:18439900
in HEK293
a_re371( Apoptosis  map ):
influenceDelete: re to reactants
engagement of mTOR in mTORC1 does not titrate it out of mTORC2


Modifications:
In compartment: Cytoplasm
  1. RPTOR@Cytoplasm map

  2. RPTOR|​S722_pho|​S792_pho@Cytoplasm map

Participates in complexes:
In compartment: Cytoplasm

  1. 14-3-3*|​unk:​RPTOR|​S722_pho|​S792_pho@Cytoplasm map

  2. (MTOR|​S1261_pho|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho)|​active@Cytoplasm map
  3. MLST8:​MTOR:​RPTOR@Cytoplasm map
  4. MLST8:​MTOR:​RPTOR|​pho@Cytoplasm map
  5. MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map
  6. MLST8:​MTOR:​PRAS40*:​RPTOR@Cytoplasm map
  7. FKBP8:​MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map
  8. DEPDC6:​MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map
  9. MLST8:​MTOR:​PRAS40*|​pho:​RPTOR@Cytoplasm map
  10. EIF3*:​EIF4E*:​M7GTP*:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*@Cytoplasm map
  11. EIF3*:​EIF4E*:​M7GTP*:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*:​p70_alpha_*|​T389_pho@Cytoplasm map
  12. EIF3*:​EIF4A*:​EIF4B|​pho:​EIF4E*:​EIF4G*:​M7GTP*:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PABP1*:​RPS6|​S235_pho|​S236_pho|​S240_pho|​S244_pho|​S247_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*@Cytoplasm map

In compartment: Membrane Lysosome

  1. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map

  2. MLST8:​MTOR|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  3. MLST8:​MTOR|​S2448_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  4. MLST8:​MTOR|​S1261_pho|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  5. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  6. DEPTOR:​MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map
  7. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S863_pho|​S877_pho@Membrane Lysosome map
  8. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map
  9. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map

In compartment: Nucleus

  1. MLST8:​MTOR:​RPTOR|​unk@Nucleus map

  2. MLST8:​MTOR:​PPARGC1A:​RPTOR|​pho:​YY1@Nucleus map

In compartment: PML Body

  1. MLST8:​MTOR:​RPTOR|​unk@PML Body map

Participates in reactions:
As Reactant or Product:

  1. DEPDC6@Cytoplasm map + MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map map DEPDC6:​MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map

  2. MLST8:​MTOR:​RPTOR@Cytoplasm map + PRAS40*@Cytoplasm map map MLST8:​MTOR:​PRAS40*:​RPTOR@Cytoplasm map
  3. MLST8:​MTOR:​PRAS40*:​RPTOR@Cytoplasm map map MLST8:​MTOR:​PRAS40*|​pho:​RPTOR@Cytoplasm map
  4. 14-3-3*|​unk@Cytoplasm map + MLST8:​MTOR:​PRAS40*|​pho:​RPTOR@Cytoplasm map map MLST8:​MTOR:​RPTOR@Cytoplasm map + 14-3-3*|​unk:​PRAS40*|​pho@Cytoplasm map
  5. RPTOR@Cytoplasm map map RPTOR|​S722_pho|​S792_pho@Cytoplasm map
  6. MLST8@Cytoplasm map + MTOR@Cytoplasm map + RPTOR@Cytoplasm map map MLST8:​MTOR:​RPTOR@Cytoplasm map
  7. 14-3-3*|​unk@Cytoplasm map + RPTOR|​S722_pho|​S792_pho@Cytoplasm map map 14-3-3*|​unk:​RPTOR|​S722_pho|​S792_pho@Cytoplasm map
  8. MLST8:​MTOR:​RPTOR@Cytoplasm map map MLST8:​MTOR:​RPTOR|​pho@Cytoplasm map
  9. MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map map MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map
  10. MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map map MLST8:​MTOR:​RPTOR|​unk@Nucleus map
  11. MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map map MLST8:​MTOR:​RPTOR|​pho@Cytoplasm map
  12. MLST8:​MTOR:​RPTOR|​unk@Nucleus map map MLST8:​MTOR:​RPTOR|​unk@PML Body map
  13. YY1@Nucleus map + PPARGC1A@Nucleus map + MLST8:​MTOR:​RPTOR|​unk@Nucleus map map MLST8:​MTOR:​PPARGC1A:​RPTOR|​pho:​YY1@Nucleus map
  14. MLST8:​MTOR:​RPTOR@Cytoplasm map map MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map
  15. MLST8:​MTOR:​RPTOR|​pho@Cytoplasm map map MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map
  16. MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map + FKBP8@Cytoplasm map map FKBP8:​MLST8:​MTOR:​RPTOR|​unk@Cytoplasm map
  17. PRAS40*@Cytoplasm map + MLST8@Cytoplasm map + RPTOR@Cytoplasm map + MTOR|​S2448_pho@Cytoplasm map map MLST8:​MTOR|​S2448_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  18. PRAS40*@Cytoplasm map + MLST8@Cytoplasm map + RPTOR@Cytoplasm map + MTOR@Cytoplasm map + RAC1@Cytoplasm map map s_s_akt1_s873
  19. s_s_akt1_s873 map MLST8:​MTOR|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  20. MLST8:​MTOR|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map map MLST8:​MTOR|​S1261_pho|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  21. MLST8:​MTOR|​S1261_pho|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  22. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S863_pho|​S877_pho@Membrane Lysosome map
  23. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S863_pho|​S877_pho@Membrane Lysosome map map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map
  24. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map
  25. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map + PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho@Membrane Lysosome map
  26. DEPTOR@Cytoplasm map map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map + DEPTOR:​MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map
  27. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map map (MTOR|​S1261_pho|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho)|​active@Cytoplasm map
  28. (MTOR|​S1261_pho|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho)|​active@Cytoplasm map + EIF3*:​EIF4E*:​M7GTP*:​mRNA generic*:​p70_alpha_*@Cytoplasm map map EIF3*:​EIF4E*:​M7GTP*:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*:​p70_alpha_*|​T389_pho@Cytoplasm map
  29. EIF3*:​EIF4E*:​M7GTP*:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*:​p70_alpha_*|​T389_pho@Cytoplasm map map EIF3*:​EIF4E*:​M7GTP*:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*@Cytoplasm map + p70_alpha_*|​T389_pho@Cytoplasm map + 4E-BP*|​T37_pho|​T46_pho|​S65_pho|​T70_pho@Cytoplasm map
  30. EIF3*:​EIF4E*:​M7GTP*:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*@Cytoplasm map + RPS6|​S235_pho|​S236_pho|​S240_pho|​S244_pho|​S247_pho@Cytoplasm map + EIF4B|​S422_pho@Cytoplasm map + EIF4G*@Cytoplasm map + PABP1*@Cytoplasm map + EIF4A*@Cytoplasm map map EIF3*:​EIF4A*:​EIF4B|​pho:​EIF4E*:​EIF4G*:​M7GTP*:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PABP1*:​RPS6|​S235_pho|​S236_pho|​S240_pho|​S244_pho|​S247_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*@Cytoplasm map
  31. EIF3*:​EIF4A*:​EIF4B|​pho:​EIF4E*:​EIF4G*:​M7GTP*:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PABP1*:​RPS6|​S235_pho|​S236_pho|​S240_pho|​S244_pho|​S247_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*@Cytoplasm map map mRNA translation@Cytoplasm map

As Catalyser:

  1. DEPDC6@Cytoplasm map map DEPDC6|​pho@Cytoplasm map

  2. rHIF1A@Nucleus map map HIF1A@Cytoplasm map
  3. MLST8:​MTOR:​PRAS40*:​RPTOR@Cytoplasm map map MLST8:​MTOR:​PRAS40*|​pho:​RPTOR@Cytoplasm map
  4. degraded map Autophagy@Cytoplasm map
  5. S6K*@Cytoplasm map map S6K*|​pho@Cytoplasm map
  6. 4E-BP*@Cytoplasm map map 4E-BP*|​pho@Cytoplasm map
  7. gCytochrome_C*@Nucleus map map rCytochrome_C*@Nucleus map
  8. gPPARGC1A@Nucleus map map rPPARGC1A@Nucleus map
  9. gESRRA@Nucleus map map rESRRA@Nucleus map
  10. gNRF1@Nucleus map map rNRF1@Nucleus map
  11. gPPARGC1B@Nucleus map map rPPARGC1B@Nucleus map
  12. gATP5G1@Nucleus map map rATP5G1@Nucleus map
  13. gCOX5A@Nucleus map map rCOX5A@Nucleus map
  14. gIDH3A@Nucleus map map rIDH3A@Nucleus map
  15. gPHLPP*@Nucleus map map rPHLPP*@Nucleus map
  16. p70_beta_*@Cytoplasm map map p70_beta_*|​pho@Cytoplasm map
  17. ATG13:​FIP200*:​ULK*@Cytoplasm map map ATG13|​pho:​FIP200*:​ULK*|​pho@Cytoplasm map
  18. MLST8:​MTOR|​S1261_pho|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  19. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S863_pho|​S877_pho@Membrane Lysosome map
  20. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map
  21. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map + PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho@Membrane Lysosome map
  22. (MTOR|​S1261_pho|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho)|​active@Cytoplasm map + EIF3*:​EIF4E*:​M7GTP*:​mRNA generic*:​p70_alpha_*@Cytoplasm map map EIF3*:​EIF4E*:​M7GTP*:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*:​p70_alpha_*|​T389_pho@Cytoplasm map

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