RPA2

Protein RPA2 map

Identifiers
replication protein A2, 32kDa
HUGO:RPA2 HGNC:10290 ENTREZ:6118 UNIPROT:P15927 GENECARDS:RPA2 REACTOME:99865 KEGG:6118 ATLASONC:RPA2ID42146ch1p35 WIKI:RPA2

Maps_Modules
 DNA repair  map  / S_PHASE_CHECKPOINT  map
 DNA repair  map  / S_CC_PHASE  map
 DNA repair  map  / HR  map
 DNA repair  map  / NER  map
 DNA repair  map  / MMR  map

References
PMID:19809470, PMID:15703371, PMID:19847258, PMID:16697054, PMID:12648680, PMID:17884153, PMID:11900249
For S-phase checkpoint
PMID:15459660,PMID:17102137, PMID:17116885, PMID:17296725, PMID:19793801, PMID:17582221, PMID:18677104

RPA2@Nucleus

References
d_re355( DNA repair  map ):
For role of TIM1*/TIPIN in S-phase checkpoint, replication arrest, stalled replication forks stabilisation and DNA repair during S-phase:
PMID:17102137, PMID:17116885, PMID:17296725, PMID:19793801, PMID:17582221

RPA2|​pho@default

References
d_re43:( DNA repair  map ) PMID:16731533

RPA2@default

References
d_re43:( DNA repair  map ) PMID:16731533


Modifications:
In compartment: Nucleus
  1. RPA2@Nucleus map

In compartment: default

  1. RPA2@default map

  2. RPA2|​pho@default map

Participates in complexes:
In compartment: Nucleus

  1. EXO1:​PCNA:​RFC*:​RPA1:​RPA2:​RPA3:​hMutL*:​hMutS*@Nucleus map

In compartment: default

  1. RPA1:​RPA2:​RPA3@default map

  2. RPA1:​RPA2|​pho:​RPA3@default map
  3. POLD*:​RPA1:​RPA2|​pho:​RPA3@default map
  4. RAD52:​RPA1:​RPA2|​pho:​RPA3@default map
  5. RPA1:​RPA2:​RPA3:​SMARCAL1|​pho@default map
  6. ATRIP:​ATR|​pho:​CLSPN|​pho:​RPA1:​RPA2:​RPA3@default map
  7. BRCA1:​BRCA2:​FANCD2|​pho:​FANCI|​pho:​FANCJ*:​FANCN*:​RPA1:​RPA2:​RPA3@default map
  8. ATRIP:​ATR|​pho:​CHEK1|​pho:​CLSPN|​pho:​RPA1:​RPA2:​RPA3:​TIM1*:​TIPIN@default map
  9. BRCA1:​BRCA2:​FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​FANCJ*:​FANCN*:​RPA1:​RPA2:​RPA3@default map
  10. CHTF18:​PCNA:​POLD*:​POLE*:​POLK:​RFC*:​RPA1:​RPA2|​pho:​RPA3:​XRCC1|​pho@default map
  11. CDK7:​CyclinH*:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@default map
  12. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​RPA1:​RPA2:​RPA3:​TOP3A@default map
  13. CDK7:​CyclinH*:​ERCC1:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*:​XPF*:​XPG*@default map
  14. CDC45:​CDC6:​CDT1:​MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7:​ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*:​POLA*:​PRIM*:​RPA1:​RPA2:​RPA3@default map

Participates in reactions:
As Reactant or Product:

  1. d_s2743 + d_s834 + EXO1@default map + RPA1:​RPA2:​RPA3@default map + PCNA@default map + RFC*@Nucleus map map EXO1:​PCNA:​RFC*:​RPA1:​RPA2:​RPA3:​hMutL*:​hMutS*@Nucleus map

  2. RPA1:​RPA2:​RPA3@default map + SMARCAL1|​pho@default map map RPA1:​RPA2:​RPA3:​SMARCAL1|​pho@default map
  3. CDK7:​CyclinH*:​MNAT1:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XPB*:​XPD*@default map + RPA1:​RPA2|​pho:​RPA3@default map + XAB2:​XPA|​S196_pho@default map map CDK7:​CyclinH*:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@default map
  4. CDK7:​CyclinH*:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@default map + ERCC1@default map + XPF*@default map + XPG*@default map map CDK7:​CyclinH*:​ERCC1:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*:​XPF*:​XPG*@default map
  5. BRCA1|​S988_pho|​S1387_pho|​S1423_pho|​S1497_pho|​S1524_pho|​active@default map + BRCA2@default map + FANCJ*@default map + RPA1:​RPA2:​RPA3@default map + FANCN*@default map + FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho@default map map BRCA1:​BRCA2:​FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​FANCJ*:​FANCN*:​RPA1:​RPA2:​RPA3@default map
  6. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map + TOP3A@default map + RPA1:​RPA2:​RPA3@default map map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​RPA1:​RPA2:​RPA3:​TOP3A@default map
  7. POLE*@default map + POLD*@default map + RFC*@Nucleus map + PCNA@default map + CHTF18@default map + POLK@default map + XRCC1|​pho@default map + RPA1:​RPA2|​pho:​RPA3@default map map CHTF18:​PCNA:​POLD*:​POLE*:​POLK:​RFC*:​RPA1:​RPA2|​pho:​RPA3:​XRCC1|​pho@default map
  8. RAD52@default map + RPA1:​RPA2|​pho:​RPA3@default map map RAD52:​RPA1:​RPA2|​pho:​RPA3@default map
  9. BRCA1:​BRCA2:​FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​FANCJ*:​FANCN*:​RPA1:​RPA2:​RPA3@default map map BRCA1:​BRCA2:​FANCD2|​pho:​FANCI|​pho:​FANCJ*:​FANCN*:​RPA1:​RPA2:​RPA3@default map
  10. ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*@default map + MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7@default map + CDT1@default map + CDC6@default map + CDC45@default map + POLA*@default map + PRIM*@default map + RPA1@Nucleus map + RPA2@Nucleus map + RPA3@Nucleus map map CDC45:​CDC6:​CDT1:​MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7:​ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*:​POLA*:​PRIM*:​RPA1:​RPA2:​RPA3@default map
  11. RPA2@default map map RPA2|​pho@default map
  12. RPA1@default map + RPA2|​pho@default map + RPA3@default map map RPA1:​RPA2|​pho:​RPA3@default map
  13. POLD*@default map + RPA1:​RPA2|​pho:​RPA3@default map map POLD*:​RPA1:​RPA2|​pho:​RPA3@default map
  14. ATRIP:​ATR|​pho@default map + CLSPN|​pho@default map + RPA1:​RPA2:​RPA3@default map map ATRIP:​ATR|​pho:​CLSPN|​pho:​RPA1:​RPA2:​RPA3@default map
  15. RPA1@default map + RPA2@default map + RPA3@default map map RPA1:​RPA2:​RPA3@default map
  16. ATRIP:​ATR|​pho:​CLSPN|​pho:​RPA1:​RPA2:​RPA3@default map + TIPIN@default map + TIM1*@default map + CHEK1|​pho|​active@default map map ATRIP:​ATR|​pho:​CHEK1|​pho:​CLSPN|​pho:​RPA1:​RPA2:​RPA3:​TIM1*:​TIPIN@default map

As Catalyser:

  1. S phase@default map map G2 phase@default map

  2. gGG-NER_DNA_st2*@Nucleus map map gTC-NER_GG-NER_DNA_st3*@Nucleus map
  3. gHR_DNA_st2*@Nucleus map map gHR_DNA_st3*@Nucleus map
  4. gHR_DNA_st3*@Nucleus map map gHR_DNA_st4*@Nucleus map
  5. gTC-NER_DNA_st2*@Nucleus map map gTC-NER_GG-NER_DNA_st3*@Nucleus map
  6. gFanconi_DNA_st2*@Nucleus map map gFanconi_DNA_st3*@Nucleus map
  7. gFanconi_DNA_st4*@Nucleus map map gFanconi_DNA_st5*@Nucleus map
  8. gFanconi_DNA_st5*@Nucleus map map gTC-NER_GG-NER_DNA_st4*@Nucleus map
  9. gFanconi_DNA_st4*@Nucleus map map gHR_DNA_st2*@Nucleus map
  10. gSSA_DNA_st2*@Nucleus map map gSSA_DNA_st3*@Nucleus map
  11. gTC-NER_GG-NER_DNA_st3*@Nucleus map map gTC-NER_GG-NER_DNA_st4*@Nucleus map + Modified 24-32 nucleotides fragment@default map
  12. gTC-NER_GG-NER_DNA_st4*@Nucleus map + dNTPs@Nucleus map map gTC-NER_GG-NER_DNA_st5*@Nucleus map
  13. gMMR_DNA_st2*@Nucleus map map gMMR_DNA_st3*@Nucleus map
  14. gMMR_DNA_st3*@Nucleus map map gMMR_DNA_st4*@Nucleus map
  15. TOPBP1@default map + ATRIP:​ATR|​pho@default map + CLSPN|​pho@default map + RAD17|​pho@default map map ATRIP:​ATR|​pho:​CLSPN|​pho:​RAD17|​pho:​TOPBP1@default map
  16. ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*@default map + MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7@default map + CDT1@default map + CDC6@default map + CDC45@default map + POLA*@default map + PRIM*@default map + RPA1@Nucleus map + RPA2@Nucleus map + RPA3@Nucleus map map CDC45:​CDC6:​CDT1:​MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7:​ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*:​POLA*:​PRIM*:​RPA1:​RPA2:​RPA3@default map
  17. No DNA replicarion@default map map DNA replicarion@default map
  18. RAD1@default map + RAD9*|​pho@default map + HUS1@default map map HUS1:​RAD1:​RAD9*|​pho@default map
  19. HUS1:​RAD1:​RAD9*|​pho@default map + RAD17@default map + RFC*@Nucleus map map HUS1:​RAD1:​RAD17:​RAD9*:​RFC*@default map

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