RASA1

Protein RASA1 map

Identifiers
RAS p21 protein activator (GTPase activating protein) 1
RASA
HUGO:RASA1 HGNC:9871 ENTREZ:5921 UNIPROT:P20936 GENECARDS:RASA1 REACTOME:63760 KEGG:5921 ATLASONC:GC_RASA1 WIKI:RASA1

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / CYTOSKELETON_POLARITY  map

References
PMID:8537347
PMID:10769036
GAP activity of ARHGAP5 is abrogated by binding to RASA1 (p120GAP)
PMID:8360177
RASA1 is a GAP for HRAS.
PMID:18829532
RasGAP actvity of RASA1 is reduced when associated with ARHGAP35 which is a specific GAP for RhoA

RASA1@Cytoplasm

References
e_re897( EMT  map ):
PMID:8537347
PMID:10769036
GAP activity of ARHGAP5 is abrogated by binding to RASA1 (p120GAP)
e_re934( EMT  map ):
PMID:8360177
RASA1 is a GAP for HRAS.
PMID:18829532
RasGAP actvity of RASA1 is reduced when associated with ARHGAP35 which is a specific GAP for RhoA
ARHGAP35 is tyrosine-phosphorylated.
The association of ARHGAP35 (p190) with RASA1 (p120) is promoted and stabilized by phosphorylation of p190 at Y1105 by PTK6..


Modifications:
In compartment: Cytoplasm
  1. RASA1@Cytoplasm map

Participates in complexes:
In compartment: Cytoplasm

  1. ARHGAP5:​RASA1@Cytoplasm map

  2. ARHGAP35|​pho:​RASA1@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. RASA1@Cytoplasm map + ARHGAP5@Cytoplasm map map ARHGAP5:​RASA1@Cytoplasm map

  2. HRAS_GAPs*@Cytoplasm map map RASA1@Cytoplasm map
  3. ARHGAP35|​pho@Cytoplasm map + RASA1@Cytoplasm map map ARHGAP35|​pho:​RASA1@Cytoplasm map

As Catalyser:

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