RAD18:RAD6*

Complex RAD18:RAD6* map


Complex composition:

  1. RAD18 map
  2. RAD6* map




RAD18:​RAD6*@default

Identifiers
NAME:RAD18:RAD6*

Maps_Modules
 DNA repair  map  / TLS  map

References
d_re168( DNA repair  map ):
PMID:18157158
Ubiquitination of PCNA by RAD6-RAD18 increases affinity of PCNA to POLH and makes switch from PCNA-POLD to PCNA-POLH and stops translation and initiates TLS pathway
PMID:15280666, PMID:18498753
d_re236( DNA repair  map ):
Recruitment of all components as POLH and RAD6/RAD18 that ubiguitinate PCNA all together activate TLS:
PMID:16824193

Confidence
REF=2 FUNC=5


Modifications:
Participates in complexes:
In compartment: default
  1. RAD18:​RAD6*@default map

Participates in reactions:
As Reactant or Product:

  1. RAD18@default map + RAD6*@default map map RAD18:​RAD6*@default map

  2. RAD18:​RAD6*@default map + POLH@default map + REV1@default map map POLH:​RAD18:​RAD6*:​REV1@default map

As Catalyser:

  1. PCNA@default map map PCNA|​K164_ubi@default map

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