RAC1B*

Protein RAC1B* map

Identifiers
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
HUGO:RAC1 HGNC:9801 ENTREZ:5879 UNIPROT:P63000 GENECARDS:RAC1 REACTOME:404635 KEGG:5879 ATLASONC:GC_RAC1 WIKI:RAC1

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / CELL_CELL_ADHESIONS  map
 EMT  map  / TIGHT_JUNCTIONS  map
 EMT  map  / CYTOSKELETON_POLARITY  map

References
PMID:21667018
PMID:16001073
Rac1B is an alternatively spliced form of Rac1 gene.
Rac1B does not lead to lamellipodia formation, or the activation of PAK1, AKT1, or c-Jun-NH2- kinase activities.
However, Rac1B retains the ability to stimulate the NF-kappa-B pathway.

RAC1B*@Cytoplasm

References
e_re1229( EMT  map ):
PMID:21667018
Rac1B is an alternatively spliced form of Rac1 gene.
Rac1B does not lead to lamellipodia formation, or the activation of PAK1, AKT1, or c-Jun-NH2- kinase activities.
However, Rac1B retains the ability to stimulate the NF-kappa-B pathway.
PMID:16001073
MMP3 can induce the expression of RACB1.
RACB1 increases the cellular levels of ROS, causing an upregulation of Snail and induction of EMT.

RAC1B*@Nucleus

References
e_re1235( EMT  map ):
PMID:16001073
RAC1B increases the cellular level of ROS, causing an upregulation of Snail and induction of EMT


Modifications:
In compartment: Cytoplasm
  1. RAC1B*@Cytoplasm map

In compartment: Nucleus

  1. RAC1B*@Nucleus map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. rRAC1@Nucleus map map RAC1B*@Cytoplasm map

    2. RAC1B*@Cytoplasm map map RAC1B*@Nucleus map
    3. RAC1B*@Nucleus map map ROS@Nucleus map

    As Catalyser:

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