PTK6

Protein PTK6 map

Identifiers
protein tyrosine kinase 6
HUGO:PTK6 HGNC:9617 ENTREZ:5753 UNIPROT:Q13882 GENECARDS:PTK6 KEGG:5753 ATLASONC:GC_PTK6 WIKI:PTK6

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / CYTOSKELETON_POLARITY  map

References
PMID:18829532
PTK6 phosphorylates ARHGAP35
RasGAP actvity of RASA1 is reduced when associated with ARHGAP35 which is a specific GAP for RhoA
ARHGAP35 is tyrosine-phosphorylated.
The association of ARHGAP35 (p190) with RASA1 (p120) is promoted and stabilized by phosphorylation of p190 at Y1105 by CSK or by PTK6.

PTK6@Cytoplasm

References
e_re931( EMT  map ):
PMID:18829532
PMID:9819392
PTK6 and CSK both can phosphorylate ARHGAP35 (p190) at Y1105
RasGAP actvity of RASA1 is reduced when associated with ARHGAP35 which is a specific GAP for RhoA
ARHGAP35 is tyrosine-phosphorylated.
The association of ARHGAP35 (p190) with RASA1 (p120) is promoted and stabilized by phosphorylation of p190 at Y1105 by CSK or by PTK6.


Modifications:
In compartment: Cytoplasm
  1. PTK6@Cytoplasm map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

      As Catalyser:

      1. ARHGAP35@Cytoplasm map map ARHGAP35|​pho@Cytoplasm map

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