Complex composition:
PRICKLE1|pho:VANGL*@Cytoplasm
Identifiers
NAME:PRICKLE1:VANGL*
References
s_wnc1_re85( Survival ):
Prickle interacts physically with Vangl
PMID:22037766
PMID:12941693
Par6 is constitutively associated with Dvl
PMID:19379695
s_wnc1_re62( Survival ):
Cthrc1 enhances formation of Wnt-Fzl-Ror2 complex
PMID:12839624
PMID:18606138
Syndecan-4 binds to Fzl, Dvl and is required for PCP MODULE.
PMID:16604063
PMID:21397842
Vangl-2 forms complex upon binding with Wnt-5
PMID:21316585
ROR2 is associated with Wnt, Fzl and CK1_epsilon
PMID:20215527
PPR binds to Fzl in both canonical and non-canonical MODULE
PMID:20093472
PMID:21380625
PMID:20579883
Confidence REF=5 FUNC=3
Modifications:
Participates in complexes:
In compartment: Cytoplasm
Participates in reactions:
As Reactant or Product:
- ROR2@Cytoplasm
+ FZD*:GDP:G_alpha_*:G_beta_*:G_gamma_*@Cytoplasm
+ WNT*@default
+ GTP@Cytoplasm
+ CK1_epsilon_*@Cytoplasm
+ CTHRC1@Cytoplasm
+ SYN4*@Cytoplasm
+ PRICKLE1|pho:VANGL*@Cytoplasm
+ PRR*@Cytoplasm
→
CK1_epsilon_*:CTHRC1:PRICKLE1|pho:PRR*:ROR2:SYN4*:VANGL*@Cytoplasm
+ GDP@Cytoplasm
- s_s_wnc1_s396 + PRICKLE1|pho@Cytoplasm
+ PAR6*@Cytoplasm
→
PRICKLE1|pho:VANGL*@Cytoplasm
As Catalyser: